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3篇 您的检索式:作者名="Rohanah"
    题名 作者 年代 出处 被引量
1The SH3 domain of HS1 protein recognizes lysine-rich polyproline motifs显示文摘Giuliano Siligardi Paolo Ruzza Rohanah Hussain Luca Cesaro Anna Maria Brunati Lorenzo A. Pinna Arianna Donella-Deana 2012Amino Acids2012,,4:1
2Cortisol facilitates the immune escape of human acute myeloid leukemia cells by inducing latrophilin 1 expression显示文摘The progression of acute myeloid leukemia(AML)—the most severe blood/bone marrow cancer—is determined by the ability of malignant cells to escape host immune surveillance.However,the systemic regulatory mechanisms underlying this phenomenon remain largely unknown.In this study,we discovered a fundamental systemic biochemical strategy that allows AML cells to employ physiological systems within the body to survive and escape immune attack.We found that AML cells use a crucial human adrenal cortex hormone(cortisol)to induce the expression of neuronal receptor latrophilin 1(LPHN1),which facilitates exocytosis.This receptor interacts with the blood plasma protein fibronectin leucine rich transmembrane protein 3(FLRT3)to cause secretion of the immune suppressor galectin-9,which impairs the anticancer activities of cytotoxic lymphoid cells.Svetlana S.Sakhnevych Inna M.Yasinska Alison M.Bratt Ouafa Benlaouer Isabel Gonçalves Silva Rohanah Hussain Giuliano Siligardi Walter Fiedler Jasmin Wellbrock Bernhard F.Gibbs Yuri A.Ushkaryov Vadim V.Sumbayev 2018Cellular & Molecular Immunology2018,15,11:0
3Spatially resolved chiroptical study of thin films of benzo[1,2-b:4,5-b’]dithiophene-based oligothiophenes by synchrotron radiation electronic circular dichroism imaging(SR-ECDi)technique显示文摘The study of the chiroptical properties of thin-film samples of two chiral benzo[1,2-b:4,5-b’]dithiophene-based oligothiophenes with optoelectronic properties was carried out at Diamond B23 beamline using the synchrotron radiation electronic circular dichroism imaging(SR-ECDi)facility.The experimental results support the hypothesis that the non-reciprocal circularly polarized absorption observed in these materials is due to the combined linear dichroism and linear birefringence contributions.The mapping at 50-μM spatial resolution revealed that several species coexist in the mesoscopic chiral domains likely due to different aggregated phases,which were identified in the films by SR-ECDi but could not be detected with benchtop ECD instruments.Gianluigi Albano Marcin Gorecki Tamas Javorfi Rohanah Hussain Giuliano Siligardi Gennaro Pescitelli Lorenzo Di Bari 2022Aggregate2022,3,5:0
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