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| 1 | Impairment of hepatic stat-3 activation and reduction of PPAR alpha activity in fructose-fed rats显示文摘 | Roglans N Vila L Farre M | 2007 | Hepatology2007，45，： | 1 |
| 2 | Diazonium salts as substrates in palladium-catalyzed cross-coupling reactions显示文摘 | Roglans A Pla-Quintana A Moreno-Manas M | 2006 | Chem Rev2006，106，： | 1 |
| 3 | Simple sugar intake and hepatocellular carcinoma: epidemiological and mechanistic insight显示文摘 | Laguna J C Alegret M Roglans N | 2014 | Nutrients2014，6，12： | 1 |
| 4 | Atorvastatin treatment induced peroxisome proliferator-activated receptor expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats显示文摘 | NURIA ROGLANS | 2002 | J Pharmacol Exp Ther2002，302，1： | 1 |
| 5 | B-type natfiuretic peptides for prediction and diagnosis of weaning failure from cardiac origin 显示文摘 | Zapata L Vera P Roglan A | 2011 | Intensive Care Med2011，37，3： | 1 |
| 6 | B-type natriuretic peptides for prediction and diagnosis of weaning failure from cardiac origin显示文摘 | Zapata L Vera P Roglan A | 2011 | Intensive Care Med2011，37，3： | 1 |
| 7 | Way back for fructose and liver metabolism:Bench side to molecular insights显示文摘The World Health Organization recommends that the daily intake of added sugars should make up no more than 10% of total energy.The consumption of sugarsweetened beverages is the main source of added sugars.Fructose,together with glucose,as a component of high fructose corn syrups or as a component of the sucrose molecule,is one of the main sweeteners present in this kind of beverages.Data from prospective and intervention studies clearly point to high fructose consumption,mainly in the form of sweetened beverages,as a risk factor for several metabolic diseases in humans.The incidence of hypertension,nonalcoholic fatty liver disease(NAFLD),dyslipidemia(mainly hypertriglyceridemia),insulin resistance,type 2 diabetes mellitus,obesity,and the cluster of many of these pathologies in the form of metabolic syndrome is higher in human population segments that show high intake of fructose.Adolescent and young adults from lowincome families are especially at risk.We recently reviewed evidence from experimental animals and human data that confirms the deleterious effect of fructose on lipid and glucose metabolism.In this present review we update the information generated in the past 2 years about high consumption of fructose-enriched beverages and the occurrence of metabolic disturbances,especially NAFLD,type 2 diabetes mellitus,and metabolic syndrome.We have explored recent data from observational and experimental human studies,as well as experimental data from animal and cell models.Finally,using information generated in our laboratory and others,we provide a view of the molecular mechanisms that may be specifically involved in the development of liver lipid and glucose metabolic alterations after fructose consumption in liquid form. | Alba Rebollo Núria Roglans Marta Alegret Juan C Laguna | 2012 | World Journal of Gastroenterology2012，18，45： | 1 |
| 8 | Bezafibratc induces acyl-CoA oxidase mRNA levels and fatty acid poroxisomal beta-oxidation in rat white adipose tissue显示文摘 | VAZQUEZ M ROGLANS N CABRERO A | 2001 | Mol Cell Biochem2001，216，： | 1 |
| 9 | B type natriuretic peptides for prediction and diagnosis of weaning failure from cardiac origin显示文摘 | Zapata L Vera P Roglan A | 2011 | Intensive Care Med2011，37，3： | 1 |
| 10 | Fibrate treatment does not modify the expression of acylcoenzyme A oxidase in human liver显示文摘 | Roglans N Bellido A Rodriguez C | 2002 | Clin Pharmacol Ther2002，72，6： | 1 |
| 11 | B- type natriuretic peptides for prediction and diagnosis of weaning failure from cardiac origin 显示文摘 | Zapata L Vera P Roglan A | 2011 | Intensive Care Med2011，37，3： | 1 |
| 12 | Impairment of hepatic Stat‐3 activation and reduction of PPARα activity in fructose‐fed rats显示文摘 | Núria Roglans Laia Vilà Mireia Farré Marta Alegret Rosa María Sánchez Manuel Vázquez‐Carrera Juan Carlos Laguna | 2007 | Hepatology2007，，3： | 1 |
| 13 | Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism 显示文摘 | Vila L Roglans N Alegret M | 2008 | Hepatology2008，48，5： | 1 |
| 14 | Suppressor of cytokine signaling-3(SOCS-3) and a deficit of serine/threonine(Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism显示文摘 | Vila L Roglans N Alegret M | 2008 | Hepatology2008，48，： | 1 |
| 15 | Direct and highly enantioselective synthesis of ferrocenes with planar chiraty by (-)-sparteine-mediated lithiation显示文摘 | Tinkl M Roglans A | 1996 | J Am Chem Soc1996，118，3： | 1 |
| 16 | Impairment of hepatic Stat-3 activa?tion and reduction of PP ARalpha activity in fructose-fed rats显示文摘 | Roglans N Vila L Farre M | 2007 | Hepa?tology2007，45，： | 1 |
| 17 | Metabolic alterations and in- creased liver mTOR expression precede the development of autoim- mune disease in a murine model of lupus erythematosus 显示文摘 | Vila L Roglans N Baena M | 2012 | PLoS One2012，，： | 1 |
| 18 | B-type natriuretic peptides for prediction and diagnosis of weaning failure from cardiac origin显示文摘 | Zapata L Vera P Roglan A | 2011 | Intensive Care Med2011，37，3： | 1 |
| 19 | The EBR-Ⅱ probabilistie risk assessment: Lessons learned regarding passive safety显示文摘 | HILL D J RAGLAND W A ROGLANS J | 1998 | Reliab Eng Syst Saf1998，62，： | 1 |
| 20 | B - type natriuretic peptides for prediction and diagnosis of weaning failure from cardiac origin 显示文摘 | Zapata L Vera P Roglan A | 2011 | Intensive Care Med2011，37，3： | 1 |
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