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| 1 | Effect of ketotifen fumarate on experimental autoimmune orchitis and torsion of the spermatic cord显示文摘The aim of this work was to study effects of ketotifen fumarate(KF)on prevention of tissue damage in testes of rats with experimental autoimmune orchitis(EAO)and on the contralateral testis in a model of prolonged testicular cord torsion(TCT).Rats with EAO or TCT were injected intraperitoneally once daily with KF or saline solution(vehicle group).Incidence and severity of testicular damage were evaluated by histopathology using an EAO score or a Johnsen score.Mast cells(MC)were identified by histochemistry and quantified.In EAO model,KF significantly reduced severity of histopathological testicular damage compared to rats in the vehicle group.KF also reduced the number of testicular MC compared to vehicle group.Similarly,in TCT model,multifocal damage of the contralateral testis was observed 30 days after testicular torsion characterized by sloughing of the germinal epithelium,seminiferous tubule atrophy,and interstitial edema.Focal signs of inflammation and fibrosis of seminiferous tubular walls were also observed.In contrast,sections of contralateral testis of rats injected with KF and killed 30 days after surgery showed normal histological features.A significant decrease in the number of MC was observed in rats treated with KF compared to untreated animals.In conclusion,we demonstrated that treatment with KF reduced testicular inflammatory process and MC infiltrates in both EAO and TCT models.The results suggest a promising treatment for infertile male patients with testicular pathologies associated with inflammation and germ cell loss. | Diego Moreno Cristian M Sobarzo Livia Lustig Marcelo G Rodriguez Pena Vanesa Anabella Guazzone | 2020 | Asian Journal of Andrology2020，22，1： | 3 |
| 2 | Carbon nanotubes for electrochemical biosensing显示文摘 | Rivas G A Rubianes M D Rodriguez M C | 2007 | Talanta2007，74，3： | 1 |
| 3 | Simulation platform for MIMO systems 显示文摘 | Bazdreseh M Rodriguez Guisantes G | 2006 | Communications and Computers2006，27，1： | 1 |
| 4 | Chemical composition of lipophilic extractives from jute (Corchorus capsularis)fibers used for manufacturing of high-quality paper pulps 显示文摘 | Rio Andrade J C Marques G Rodriguez Garcia M I | 2009 | Industrial Crops and Products2009，30，： | 1 |
| 5 | 'Very early' intrahepatic cholangiocarcinoma in cirrhotic patients:should liver transplantation be reconsidered in these patients?显示文摘 | Sapisochin G Rodriguez de Lope C Gastaca M | 2014 | Am J transplant2014，14，3： | 1 |
| 6 | The age of multilevel converters arrives显示文摘 | L G Franquelo J Rodriguez J I Leon S Kouro R Portillo and M A M Prats | | 0，，02： | 1 |
| 7 | Soilbiota and exotic plant invasion 显示文摘 | CALLAWAY R M THELEN G C RODRIGUEZ A | 2004 | Nature2004，427，6976： | 1 |
| 8 | Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 显示文摘 | MACIAG A DAINESE E RODRIGUEZ G M | 2007 | J Bacteriol2007，189，3： | 1 |
| 9 | preimplantation genetic diagnosis for spinal muscular atrophy type I 显示文摘 | Fallon L Harton GL Sisson ME Rodriguez E Field LK Fugger EF Geltinger M Sun Y Dorfmann A Schoener C Bick Dm Schulman J Levinson G Black SH | 1999 | Neurology1999，53，： | 1 |
| 10 | Assessing representativeness of the protected natural areas in Costa Rica for conserving biodiversity: A preliminary gap analysis 显示文摘 | Powell G V N Barborak J Rodriguez M | 2000 | Biological Conservation2000，93，： | 1 |
| 11 | Direct power control of DFIG-based wind turine under unbalanced grid vol- tage显示文摘 | ABAD G RODRIGUEZ M A IWANSKI G | 2010 | IEEE Trans on Power Electronics2010，25，2： | 1 |
| 12 | Baseline of butyltin pollution in coastal sediments within the Basque Country (northern Spain), in 2007-2008显示文摘 | Rodriguez J G~ Solaun O Larreta J Segarra M J B Franco J Alonso J I G Sariego C Valencia V Borja A | 2010 | Marine Pollution Bulletin2010，60，1： | 1 |
| 13 | Removal of Cr( Ⅵ ) from wastewaters at semi-industrial electrochemi- cal reactors with rotating ring electrodes 显示文摘 | Rodriguez R M G Mendoza V Puebla H | 2009 | J Hazardous Mater2009，163，23： | 1 |
| 14 | Growth, water rela- tions, and accumulation of organic and inorganic solutes in roots of maize seedlings during salt stress显示文摘 | Rodriguez H G Roberts J K M Jordan W R | 1997 | Plant Physiol1997，113，3： | 1 |
| 15 | Restoring the endothelium of cryopreserved arterial grafts:co-culture of venous and arterial endothelial cell显示文摘 | Pascual G Escudero C Rodriguez M | 2004 | Cryobiology2004，49，3： | 1 |
| 16 | Morphology and characterization of laser clad composite NiCrBSi-WC coatings on stainless steel显示文摘 | TOBAR M J ALVAREZ C AMADO J M RODRIGUEZ G YANEZ A | 2006 | Surface & Coatings Technology2006，200，： | 1 |
| 17 | Assessing representativeness of protected natural areas in Costa Rica for protecting biodiversity:A preliminary gab analysis显示文摘 | Powell G V N Barborak J Rodriguez M | 2000 | Biological Conservation2000，93，： | 1 |
| 18 | Central adiposity in children born small and large for gestational age显示文摘 | Biosca M Rodriguez G Ventura P | 2011 | NutrHosp2011，26，5： | 1 |
| 19 | Inhibition of neuronal nitric oxide synthase activity by Nl-acetyl-5- methoxykynuramine, a brain metabolite of melatonin显示文摘 | Leon J Escames G Rodriguez M I | 2006 | J Neurochem2006，98，6： | 1 |
| 20 | Heat requirements in a caD- ciner of CaCO3 integrated in a CO2 capture system using CaO显示文摘 | Rodriguez N Alonso M Grasa G | 2008 | Chemical Engineering Journal2008，138，13： | 1 |
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