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| 1 | Cytokines,cytokine gene polymorphisms and Helicobacter pylori infection:Friend or foe?显示文摘Helicobacter pylori(H.pylori)is a flagellated,spiralshaped,microaerophilic Gram-negative bacillus that colonises the gastric mucosa of more than 50%of the human population.Infection is a risk factor for gastritis,ulcer disease and stomach cancer.Immunity against H.pylori is mainly related to Th1/Th17 skewing,and the activation of regulatory T cells is the main strategy used to limit inflammatory responses,which can result in the pathogen persistence and can lead to chronic gastrointestinal diseases,including cancer.Furthermore,host genetic factors that affect cytokines may determine differences in the susceptibility to many diseases.In this review,we present the cytokine profiles and the main cytokine gene polymorphisms associated with resistance/susceptibility to H.pylori and discuss how such polymorphisms may influence infection/disease outcomes. | Camila A Figueiredo Cintia Rodrigues Marques Ryan dos Santos Costa Hugo Bernardino F da Silva Neuza M Alcantara-Neves | 2014 | World Journal of Gastroenterology2014，20，18： | 11 |
| 2 | Role of endoglin and VEGF family expression in colorectal cancer prognosis and anti-angiogenic therapies显示文摘Colorectal cancer(CRC)is one of the cancer models and most of the carcinogenic steps are presently well understood.Therefore,successful preventive measures are currently used in medical practice.However,CRC is still an important public health problem as it is the third most common cancer and the fourth most frequent cause of cancer death worldwide.Nowadays,pathologic stage is a unique and well-recognized prognostic indicator,however,more accurate indicators of the biologic behavior of CRC are expected to improve the specificity of medical treatment.Angiogenesis plays an important role in the growth and progression of cancer but its role as a prognostic factor is still controversial.Probably the most important clinical implication of tumor angiogenesis is the development of anti-angiogenic therapy.The goal of this review is to critically evaluate the role of angiogenic markers,assessed by either endoglin-related microvessel density or expression of vascular endothelial growth factor family members in the CRC setting and discuss the role of these angiogenic markers in antiangiogenic therapies. | Sandra F Martins Rui M Reis Antonio Mesquita Rodrigues Fátima Baltazar Adhemar Longatto Filho | 2011 | World Journal of Clinical Oncology2011，2，6： | 9 |
| 3 | Response surface analysis and sinulation as tool for bioprocess design and optimization显示文摘 | Kalil S J Maugeri F Rodrigues M I | 2000 | Process Biochemistry2000，35，6： | 1 |
| 4 | Three-Dimensional Modeling of Vertical-Horizontal Rolling Process显示文摘 | XIONG Shang-wu Rodrigues J M C Martins P A F | 2003 | Finite Elements in Analysis and Design2003，39，： | 1 |
| 5 | Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid 显示文摘 | Silva R F Rodrigues C M Brites D | 2001 | J Hepatol2001，34，3： | 1 |
| 6 | The measurement of coal porosity with different gases显示文摘 | Rodrigues C F Lenos M J | 2002 | International Journal of Coal Geology2002，48，34： | 1 |
| 7 | Response surface analysis and simulation as a tool for bioprocess design and optimization显示文摘 | Kalil S J Maugeri F Rodrigues M I | 2000 | Process Biochemistry2000，35，： | 1 |
| 8 | Creatine kinase and lactate dehydrogenase responses after upper - body resistance exercise with different rest intervals 显示文摘 | Rodrigues B M Dantas E de Salles B F | 2010 | J Strength Cond Res2010，24，6： | 1 |
| 9 | Three-dimensional modelling of the vertical- horizontal rolling process 显示文摘 | XIONG Shang-wu Rodrigues J M C Martins P A F | 2003 | Finite Elements in Analysis and Design2003，39，11： | 1 |
| 10 | Thermal stress responses in antarctic yeast, glaciozyma antarctica PI12, characterized by real-time quantitative PCR显示文摘 | Boo S Y Wong C M Rodrigues K F | 2013 | Polar Biology2013，36，3： | 1 |
| 11 | The benefits of cardiac rehabilitation in coronary heart disease: A gender issue? 显示文摘 | Diana Anjo M a rio Santos Parr f cia Rodrigues | 2014 | Revista Portuguesa de Cardiologia2014，33，2： | 1 |
| 12 | Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin显示文摘 | Silva R F Rodrigues C M Brites D | 2002 | Pediatr Res2002，51，4： | 1 |
| 13 | Response surface analysis and simulation as a tool for bioproeess design and optimization 显示文摘 | Kalil S J Maugeri F Rodrigues M I | 2000 | Pro- gress Biochemistry2000，35，6： | 1 |
| 14 | High level Escherichla coli expression and production of a bivalent humanized antibody fragment显示文摘 | P Carter R F Kelley M L Rodrigues | 1992 | Nat Biotechnol1992，10，2： | 1 |
| 15 | Influence of through-thickness crack profile on plasticity induced crack closure显示文摘 | BRANCO R RODRIGUES D M ANTUNES F V | 2008 | Fatigue & Facture of Engineering Materials & Structures2008，31，2： | 1 |
| 16 | A simple,highly visual in vivo screen for anaplastic lymphoma kinase inhibitors显示文摘 | Rodrigues F S Yang X Nikaido M | 2012 | ACS Chem Biol2012，7，12： | 1 |
| 17 | Effects of dry grinding on two kaolins of different degrees of crystallinity显示文摘 | Garcia F G Abrio M T R Rodrigues M G | | 0，，06： | 1 |
| 18 | Response surface analysis and simulation as a tool for bioprocess design and optimization 显示文摘 | Kalil J Maugeri F Rodrigues M I | 2000 | Process Biochem2000，35，： | 1 |
| 19 | Kefir adminis- tration reduced progression of renal injury in STZ-diabetic rots by lowering oxidative stress显示文摘 | Punaro G R Maciel F R Rodrigues A M | 2014 | Nitric Oxide2014，37，： | 1 |
| 20 | Antiulcerogenic activity of Alchornea castaneaefolia:Effects on somatostatin,gastrin and prostaglandin显示文摘 | Hiruma-Lima C A Calvo T B Rodrigues C M Andrade F D Souza-Brito A R M | 2006 | Journal of Ethnopharmacology2006，104，1： | 1 |
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