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| 1 | Neutropenic enterocolitis显示文摘Neutropenic colitis is a severe condition usually affecting immunocompromised patients. Its exact pathogenesis is not completely understood. The main elements in disease onset appear to be intestinal mucosal injury together with neutropenia and the weakened immune system of the afflicted patients. These initial conditions lead to intestinal edema, engorged vessels, and a disrupted mucosal surface, which becomes more vulnerable to bacterial intramural invasion. Chemotherapeutic agents can cause direct mucosal injury(mucositis) or can predispose to distension and necrosis, thereby altering intestinal motility. This article aims to review current concepts regarding neutropenic colitis' pathogenesis, diagnosis, and management. | Fabio G Rodrigues Giovanna Dasilva Steven D Wexner | 2017 | World Journal of Gastroenterology2017，23，1： | 10 |
| 2 | Gastric neuroendocrine tumor: A practical literature review显示文摘Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group,named gastroenteropancreatic neuroendocrine tumors.They are considered rare and variable in terms of their clinical,morphological and functional characteristics and may be indolent or aggressive.They are classified into types I,II and III,according to their pathophysiology,behavior and treatment.Their diagnosis occurs,in most cases,incidentally during upper digestive endoscopies,presenting as simple gastric polyps.Most cases(type I and type II)are related to hypergastrinemia,can be multiple and are treated by endoscopic resection,whenever possible.The use of somatostatin analogs for tumor control may be one of the options for therapy,in addition to total or subtotal gastrectomy for selected cases.Adjuvant chemotherapy is only reserved for poorly differentiated neuroendocrine carcinomas.Although rare,gastric neuroendocrine tumors have an increasing incidence over the years,therefore deserving more comprehensive studies on its adequate treatment.The present study reviews and updates management recommendations for gastric neuroendocrine tumors. | Gabriel Antonio Roberto Carolina Magalhães Britto Rodrigues Renata D’Alpino Peixoto Riad Naim Younes | 2020 | World Journal of Gastrointestinal Oncology2020，12，8： | 8 |
| 3 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 4 | Biodiversity of Arbuscular Mycorrhizal (AM) fungi in mangroves of Goa in West India显示文摘Seventeen mangrove species of eight families at seven riverine and fringe habitats in Goa West India were surveyed for Arbuscular Mycorrhizal (AM) fungal diversity. Sixteen species were found to be mycorrhizal and one species showed no AM fungal colonization. AM root colonization was recorded at all seven sites and ranged from 6%-77%. Maximum root colonization was recorded in Excoecaria agallocha (77%) and minimum colonization in Avicennia marina (6%). Paris-type colonization was predominant at all sites. Auxiliary cells were recorded in roots of Acanthus ilicifolius, Ceriops tagal and Sonneretia alba. AM fungal root colonization and spore density varied by plant species and site. Site average spore density ranged from 1.84 spores·g-1 to 0.54 spores·g-1 of soil. In total, 28 AM fungal species of five genera, viz. Glomus, Acaulospora, Scutellospora, Gigaspora and Entrophospora, were recovered. Glomus was the dominant genus, three species of which were sporocarpic forms. Maximum site species richness (SR) ranged from 16 to 5. Species richness was maximum in A. ilicifolius where seven species of three genera were recovered. Based on relative abundance (RA) and isolation frequency (IF), two common species, viz. G. intraradices and A. laevis, were recovered from all seven sites. | James D'Souza Bernard Felinov Rodrigues | 2013 | Journal of Forestry Research2013，24，3： | 3 |
| 5 | Autoimmune hepatitis in childhood: The role of genetic and immune factors显示文摘Autoimmune hepatitis (AIH) is a rare chronic inflammatory disease of the liver, which affects a group of patients who lost their immunological tolerance to antigens of the liver. It is clinically characterized by hypergammaglobulinemia, elevated liver enzymes, presence of autoantibodies and histological changes. Although being rare in children, it represents a serious cause of chronic hepatic disease that can lead to cirrhosis and hepatic failure. Clinical findings, exclusion of more common liver disorders and the detection of antibodies antinuclear antibodies, smooth muscle antibodies and anti-LKM1 are usually enough for diagnosis on clinical practice. The pathogenic mechanisms that lead to AIH remain obscure, but some research findings suggest the participation of immunologic and genetic factors. It is not yet knew the triggering factor or factors that stimulate inflammatory response. Several mechanisms proposed partially explain the immunologic findings of AIH. The knowledge of immune factors evolved might result in better markers of prognosis and response to treatment. In this review, we aim to evaluate the findings of research about genetic and immune markers and their perspectives of application in clinical practice especially in pediatric population. | Priscila Menezes Ferri Liu Débora Marques de Miranda Eleonora Druve Tavares Fagundes Alexandre Rodrigues Ferreira Ana Cristina Simoes e Silva | 2013 | World Journal of Gastroenterology2013，19，28： | 3 |
| 6 | Diagnostic criteria for autoimmune hepatitis in children: A challenge for pediatric hepatologists显示文摘Autoimmune hepatitis (AIH) is a progressive inflammatory liver disorder that is rare in children and adolescents. AIH has a broad clinical spectrum and a quick response to treatment with corticosteroids and immunosuppressive medication. The available diagnosis criteria have limitations and should be evaluated in pediatric populations. Recently, some studies reported that the 2008 simplified diagnostic criteria for AIH could be used in children with high sensibility and specificity. In addition, the authors reported that globulin and immunoglobulin G levels can be used interchangeably for diagnostic purposes. They also demonstrated that the 2008 simplified criteria fail in identifying patients with fulminant hepatic failure. Here, we discuss the limitations of the use of these criteria in pediatric patients and the requirement of more studies to improve the diagnosis of AIH in children. | Priscila Menezes Ferri Alexandre Rodrigues Ferreira Débora Marques Miranda Ana Cristina Sim■es e Silva | 2012 | World Journal of Gastroenterology2012，18，33： | 3 |
| 7 | Cytotoxicity of Captafol in Mammalian Cells显示文摘The cytotoxicity of captafol, a phthalimide-derived fungicide, was evaluated in IB-RS-2 cells. Captafol at 0. 12-1 .0μg/ml blocks the cell multiplication. This effect is concentrationdependent, only partially rcversible and the degree of inhibition increases with time. The synthesis of DNA and RNA is inhibited in parallel by increasing concentrations of the | M. A. LA R. RODRIGUES AND M. D’ANGELO (Instituto Biologico, Caixa Postal 7119, 01064-970, Sao Paulo, SP Brazil) | 1994 | Biomedical and Environmental Sciences1994，7，3： | 2 |
| 8 | CO2 assimilation, photosynthetic light response curves, and water relations of 'Pera' sweet orange plants infected with Xylella fastidiosa显示文摘 | Habermann G Machado E C Rodrigues J D | 2003 | Braz J Plant Physiol2003，15，2： | 1 |
| 9 | Catalytic oxidation of isophorone to ketoisophorone over ruthenium supported MgAl-hydrotalcite 显示文摘 | Kishore D Rodrigues A E | 2007 | Catalysis Communications2007，8，7： | 1 |
| 10 | Abscisic acid inhibits type 2C protein phosphatases via the PYR/ PYL family of START proteins显示文摘 | PARK S Y FUNG P NISHIMURA N JENSEN D R FFUJII ZHAO Y LUMBA S SANTIAGO J RODRIGUES A CHOW T F | 2009 | Science2009，324，： | 1 |
| 11 | Ti-Al-V powder metallurgy (PM) via the hydrogenation dehydrogenation (HDH) process 显示文摘 | AZEVEDO C R F RODRIGUES D NETO F B | 2003 | Journal of Alloys and Compounds2003，353，12： | 1 |
| 12 | Prediction of radiation pneumonitis by dose-volume histogram parameters in lung cancer-asystematic review显示文摘 | Rodrigues G Cock M D'souza | 2004 | Radiother Oncol2004，71，2： | 1 |
| 13 | Production and characterisation of alginate microparticles incorporating Aero- monas hydrophila designed for fish oral vaccination 显示文摘 | Rodrigues A P Hirsch D Figueiredo H C P | 2006 | Process Biochem2006，41，： | 1 |
| 14 | lmmunophenotypic characterization of peripheral T lymphocytes in Mycobacterium tuberculo- sis infection and disease显示文摘 | Rodrigues D S Medeiros E A Weckx L Y | 2002 | Clin Exp Immunol2002，128，1： | 1 |
| 15 | Preparation and morphology of polypropylene/wood flour composite foams via extrusion显示文摘 | Zhang S W Rodrigue D | 2005 | PolymerComposites2005，26，6： | 1 |
| 16 | Elevated levels of bile acids in colostrum of patients with cholestasis of pregnancy are decreased following ursodeoxycholic acid therapy显示文摘 | Brites D Rodrigues C M | 1998 | J Hepatol1998，29，5： | 1 |
| 17 | Relevance of serum bile acid pro- file in the diagnosis of intrahepatic cholestasis of pregnancy in an high inci- dence area : Portugal显示文摘 | Brites D Rodrigues CM Varr Z | 1998 | Eur J Obstet Gyneco! Reprod Biol1998，80，1： | 1 |
| 18 | Viscoelasticdamping technologies, part I: Modeling and finite elementimplementation 显示文摘 | Vasques C M A * Moreira R A S Rodrigues J D | 2010 | Journal of Advanced Research inMechanical Engineering2010，1，2： | 1 |
| 19 | Effects of a Saccharomyces cerevisiae yeast on ruminal fermentation and fibre degradation of maize silages in cows显示文摘 | Guedes C M Gon alves D Rodrigues M A M | 2008 | Anim Feed Sci Tech2008，145，1： | 1 |
| 20 | The waves of containeriza- tion: shifts in global maritime transportation显示文摘 | Guerrero D Rodrigue J P | 2014 | Journal of Transport Geography2014，34，： | 1 |
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