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6篇 您的检索式:作者名="Roblin Antoine"
    题名 作者 年代 出处 被引量
1UV missile plume signatures model显示文摘Roblin Antoine Baudoux Pierre E Chervet Patrick 2002SPIE2002,4718,:1
2Ultraviolet Light Propagation under Low Visibility Atmospheric Conditions and Its Application to Aircraft Landing Aid 显示文摘LAVIGNE CLAIRE GERARD DURAND ANTOINE ROBLIN 2006Applied Optics2006,45,36:1
3UV missile plume signatures model显示文摘Antoine Roblin Pierre Emmanuel Baudoux Patrick Chervet 2002SPIE2002,4718,:1
4Ultraviolet Light Propagation under Low Visibility Atmospheric Conditions and Its Application to Aircraft Landing Aid 显示文摘LAVIGNE CLAIRE GERARD DURAND ANTOINE ROBLIN 2006Applied Optics2006,45,36:1
5Experimental and Theoretical Studies of the Aureole about a Point Source That is Due to Atmospheric Scattering in the Middle Ultraviolet 显示文摘CLAIRE LAVIGNE ROBLIN ANTOINE CHERVET PATRICK 2005Applied Optics2005,44,7:1
6Relationship between clinical remission of perianal fistulas in Crohn’s disease and serum adalimumab concentrations:A multicenter cross-sectional study显示文摘BACKGROUND Crohn’s disease(CD)is complicated by perianal fistulas in approximately 20%of patients.Achieving permanent fistula closure remains a challenge for physicians.An association between serum anti-tumor necrosis factor-αconcentrations and clinical outcomes in patients with CD has been demonstrated;however,little information is available on serum adalimumab(ADA)concentrations and remission of perianal fistulas in such patients.AIM To study the relationship between serum ADA concentrations and clinical remission of CDassociated perianal fistulas.METHODS This cross-sectional study of patients with CD-associated perianal fistulas treated with ADA was performed at four French hospitals between December 2013 and March 2018.At the time of each serum ADA concentration measurement,we collected information about the patients and their fistulas.The primary study endpoint was clinical remission of fistulas defined as the absence of drainage(in accordance with Present’s criteria),with a PDAI≤4,absence of a seton and assessment of the overall evaluation as favorable by the proctologist at the relevant center.We also assessed fistula healing[defined as being in clinical and radiological(magnetic resonance imaging,MRI)remission]and adverse events.RESULTS The study cohort comprised 34 patients who underwent 56 evaluations(patients had between one and four evaluations).Fifteen patients had clinical remissions(44%),four of whom had healed fistulas on MRI.Serum ADA concentrations were significantly higher at evaluations in which clinical remission was identified than at evaluations in which it was not[14(10-16)vs 10(2-15)μg/mL,P=0.01].Serum ADA concentrations were comparable at the times of evaluation of patients with and without healed fistulas[11(7-14)vs 10(4-16)μg/mL,P=0.69].The adverse event rate did not differ between different serum ADA concentrations.CONCLUSION We found a significant association between high serum ADA concentrations and clinical remission of CD-associated perianal fistulas.Laura Sirmai Anne-Laure Pelletier Nathalie Gault Camille Zallot Guillaume Bouguen Dominique Bouchard Pascale Roland Nicaise Marine Peyneau Sandrine Sironneau Marcelo De Carvalho Bittencourt Antoine Petitcollin Pedro Fernandez Xavier Roblin Laurent Siproudhis Laurent Abramowitz 2022World Journal of Gastroenterology2022,28,9:0
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