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62篇 您的检索式:作者名="Robaire"
    题名 作者 年代 出处 被引量
1Androgenic regulation of novel genes in the epididymis显示文摘附睾非常依赖于睾丸的存在。尽管几荷尔蒙例如 retinoids 和孕激素,并且直接分泌进 theepididymal 腔的因素例如雄激素绑定蛋白质和成纤维细胞生长因素,可能在附睾功能,睾丸激素(T)和它的代谢物起规章的作用,二氢睾酮( DHT )和雌二醇( E2 ),作为附睾结构和函数的主要管理者被接受,与起更大的作用的前者。在附睾上查明雄激素的分子的行动,三条互补途径被追求响应不同神经质的周围 x 在基因表示监视变化。当生男性征的支持被撤退,第一是沿着附睾在基因表示建立变化。第二是决定发生在雄激素的回答的顺序在 T, DHT 和 E2 的二代谢物的重新管理之上剥夺了织物。第三是在使不朽的鼠科的头 epididymidal 主细胞在基因表示上学习雄激素退却和重新管理的效果。特定的回答在每这些条件下面被观察,与在在荷尔蒙退却和重新管理之上表示的基因的礼服的期望的主要差别;然而,一些关键普通特征作为与 DHT 相比是在象生长 factor/epidermal 生长因素和 E2 的相对次要、特定的效果一样的胰岛素的基因的普通角色。一起,这些结果在附睾提供新奇卓见进雄激素规定的机制主细胞。Bernard Robaire Shayesta Seenundun Mahsa Hamzeh Sophie-Anne Lamour 2007Asian Journal of Andrology2007,9,4:5
2Changes in Gene Expression during Aging in Brown Norway 显示文摘Jeivis KM Robaire B 2005Rat Epididymis Exper Geronto2005,37,7:1
3Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophospha mide显示文摘Cai L Hales BF Robaire B 1997Biol Reprod1997,56,6:1
4Adverse effects of 5-aza-2'-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation 显示文摘OAKES C C KELLY TL ROBAIRE B 2007J Pharmacol Exp Ther2007,322,3:1
5T- he stress response in gametes and embryos after paternal chemical exposures 显示文摘HALES B F AQUILAR-MAHECHA A ROBAIRE B 2005Toxicol Appl Pharmacol2005,207,2:1
6Induction of apoptosis in the germ ceils of adult male rats after exposure to cyclophosphamide 显示文摘CAI L HALES B F ROBAIRE B 1997Biol Reprod1997,56,6:1
7Immunocyto- chemical localization of the Yf subunit of glutathione S-transferase P shows regional variation in the stai- ning of epithelial cells of the testis, efferent ducts, and epididymis of the male rat显示文摘VERI J P HERNOL L ROBAIRE B 1993J Androl1993,14,1:1
8Sperm structural and motility changes during aging in the brown Norway rat显示文摘Syntin P Robaire B 2001J Androl2001,22,2:1
9Epigenetic program- ming in the preimplantation rat embryo is disrupted by chronic paternal cyclophosphamide exposure 显示文摘BARTON TS ROBAIRE B HALES BF 2005Proc Natl Acad Sci USA2005,102,22:1
10Regulation of epididymal epithelial cell functions显示文摘Robaire B Viger RS 1995Biol Reproduc1995,52,2:1
11Changes in gene expression during aging in the Brow Norway rat epididymis 显示文摘Jervis KM Robaire B 2002J experimental gerontology2002,37,7:1
12Ageing of the male germ line显示文摘Paul C Robaire B 2013Nature Reviews Urology2013,10,4:1
13Paternal age affects fertility and progeny outcome in the brown Norway rat显示文摘Serre V Robaire B 1998Fertil Sertil1998,70,4:1
14Paternal exposure to cyclophosphamide alters cell-cell contacts and activation of embryonic transcription in the preimplantation rat embryo 显示文摘Harrouk W Robaire B Hales BF 2000Biol Reprod2000,63,1:1
15Effects of ageing on spermatozoal chromatin and its sensitivity to in vivo and in vitro oxidative challenge in the Brown Norway rat显示文摘Zubkova EV Robaire B 2006Hum Reprod2006,21,:1
16Gene expression is differentially regulated in the epididymis after orchidectomy显示文摘Ezer N Robaire B 2003Endocrinology2003,144,3:1
17Segment-specific changes with age in the expression of junctional proteins and the permeability of the blood-epididymis barrier in rats显示文摘Levy S Robaire B 0,,06:1
18Mechanisms of action of cyclophosphamide as a male-mediated developmental toxicant显示文摘Robaire B Hales BF 2003Adv Exp Med Biol2003,518,4:1
19Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophosph amide 显示文摘Cai L Hales BF Robaire B 1997Biol Reprod1997,56,6:1
20Induction of apoptosis in the germ cell of adult male rats after exposure to cyclophosphamide 显示文摘Cai L Hales BF Robaire B 1997Biol Reprod1997,56,6:1
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