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| 1 | In-situ stress measurements and stress change monitoring to monitor overburden caving behaviour and hydraulic fracture pre-conditioning显示文摘A coal mine in New South Wales is longwall mining 300 m wide panels at a depth of 160–180 m directly below a 16–20 m thick conglomerate strata. As part of a strategy to use hydraulic fracturing to manage potential windblast and periodic caving hazards associated with these conglomerate strata,the in-situ stresses in the conglomerate were measured using ANZI strain cells and the overcoring method of stress relief. Changes in stress associated with abutment loading and placement of hydraulic fractures were also measured using ANZI strain cells installed from the surface and from underground. Overcore stress measurements have indicated that the vertical stress is the lowest principal stress so that hydraulic fractures placed ahead of mining form horizontally and so provide effective pre-conditioning to promote caving of the conglomerate strata. Monitoring of stress changes in the overburden strata during longwall retreat was undertaken at two different locations at the mine. The monitoring indicated stress changes were evident 150 m ahead of the longwall face and abutment loading reached a maximum increase of about7.5 MPa. The stresses ahead of mining change gradually with distance to the approaching longwall and in a direction consistent with the horizontal in-situ stresses. There was no evidence in the stress change monitoring results to indicate significant cyclical forward abutment loading ahead of the face. The forward abutment load determined from the stress change monitoring is consistent with the weight of overburden strata overhanging the goaf indicated by subsidence monitoring. | Puller Jesse W. Mills Ken W. Jeffrey Rob G. Walker Rick J. | 2016 | International Journal of Mining Science and Technology2016，26，1： | 5 |
| 2 | Microbiota Regulate Intestinal Absorption and Metabolism of Fatty Acids in the Zebrafish显示文摘 | Ivana Semova Juliana D. Carten Jesse Stombaugh Lantz C. Mackey Rob Knight Steven A. Farber John F. Rawls | 2012 | Cell Host & Microbe2012，，3： | 1 |
| 3 | “少花钱多享受”的酒店——纽约时代广场平民M酒店显示文摘项目概况
隶属于荷兰一家酒店集团的平民M酒店坐落于纽约时代广场的中心地段,它面积达7,740平方米,包括大堂,230间具有鲜明特色的客房、阁楼、活动室和一个屋顶酒吧。酒店设计力图给客人营造宾至如归的感受。 | Rob Wagemans Erikjan Vermeulen Maarten de Geus Eva Stekelenburg Cindy Wouters Sander Vredeveld Michael Woodford Jurjen van Hulzen Jesse Nolte Adrian Gaut concrete | 2014 | 设计家2014，，4： | 0 |
| 4 | 阿姆斯特丹Happy happyjoyjoy餐厅显示文摘本案的设计灵感源于设计师受到了亚洲繁忙街道的启发,这是一间有着丰富色彩、纹理、图案、灯光和不同风格休息区的餐厅。餐厅共分为五个不同特色的空间,Concrete设计团队意在突破传统,打造一家全新室内设计理念的餐厅。在Happyhappyjoyjoy俏皮的环境中,顾客感受到的是一种快乐且幸福的就餐体验;在这里,每个人都会感受到积极向上的力量,自然洋溢脸上的微笑。 | Rob Wagemans Marc Brummelhuis Chloe Comino Erik Van Dillen Sofie Ruytenberg Jesse Nolte Bart De Beer 姜敏华 | 2015 | 现代装饰2015，0，9： | 0 |
| 5 | Mechanical environment for in vitro cartilage tissue engineering assisted by in silico models显示文摘Mechanobiological study of chondrogenic cells and multipotent stem cells for articular cartilage tissue engineering(CTE)has been widely explored.The mechanical stimulation in terms of wall shear stress,hydrostatic pressure and mechanical strain has been applied in CTE in vitro.It has been found that the mechanical stimulation at a certain range can accelerate the chondrogenesis and articular cartilage tissue regeneration.This review explicitly focuses on the study of the influence of the mechanical environment on proliferation and extracellular matrix production of chondrocytes in vitro for CTE.The multidisciplinary approaches used in previous studies and the need for in silico methods to be used in parallel with in vitro methods are also discussed.The information from this review is expected to direct facial CTE research,in which mechanobiology has not been widely explored yet. | Rob Jess Tao Ling Yi Xiong Chris J.Wright Feihu Zhao | 2023 | Biomaterials Translational2023，4，1： | 0 |
| 6 | Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases in children and adolescents.NAFLD ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis(NASH),wherein hepatocellular inflammation and/or fibrosis coexist with steatosis.Circulating microRNA(miRNA)levels have been suggested to be altered in NAFLD,but the extent to which miRNA are related to NAFLD features remains unknown.This analysis tested the hypothesis that plasma miRNAs are significantly associated with histological features of NAFLD in adolescents.AIM To investigate the relationship between plasma miRNA expression and NAFLD features among adolescents with NAFLD.METHODS This study included 81 adolescents diagnosed with NAFLD and 54 adolescents without NAFLD from the Teen-Longitudinal Assessment of Bariatric Surgery study.Intra-operative core liver biopsies were collected from participants and used to characterize histological features of NAFLD.Plasma samples were collected during surgery for miRNA profiling.A total of 843 plasma miRNAs were profiled using the HTG EdgeSeq platform.We examined associations of plasma miRNAs and NAFLD features using logistic regression after adjusting for age,sex,race,and other key covariates.Ingenuity Pathways Analysis was used to identify biological functions of miRNAs that were associated with multiple histological features of NAFLD.RESULTS We identified 16 upregulated plasma miRNAs,including miR-193a-5p and miR-193b-5p,and 22 downregulated plasma miRNAs,including miR-1282 and miR-6734-5p,in adolescents with NAFLD.Moreover,52,16,15,and 9 plasma miRNAs were associated with NASH,fibrosis,ballooning degeneration,and lobular inflammation,respectively.Collectively,16 miRNAs were associated with two or more histological features of NAFLD.Among those miRNAs,miR-411-5p was downregulated in NASH,ballooning,and fibrosis,while miR-122-5p,miR-1343-5p,miR-193a-5p,miR-193b-5p,and miR-7845-5p were consistently and positively associated with all histological features of NAFLD.Pathway analysis revealed that most common pathways of miRNAs associated with multiple NAFLD features have been associated with tumor progression,while we also identified linkages between miR-122-5p and hepatitis C virus and between miR-199b-5p and chronic hepatitis B.CONCLUSION Plasma miRNAs were associated with NAFLD features in adolescent with severe obesity.Larger studies with more heterogeneous NAFLD phenotypes are needed to evaluate miRNAs as potential biomarkers of NAFLD. | Yi-Jie Li Brittney O Baumert Nikos Stratakis Jesse A Goodrich Hao-Tian Wu Jing-Xuan He Yin-Qi Zhao Max T Aung Hong-Xu Wang Sandrah P Eckel Douglas I Walker Damaskini Valvi Michele A La Merrill Justin R Ryder Thomas H Inge Todd Jenkins Stephanie Sisley Rohit Kohli Stavra A Xanthakos Andrea A Baccarelli Rob McConnell David V Conti Lida Chatzi | 2024 | World Journal of Gastroenterology2024，30，4： | 0 |
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