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| 1 | Five trends of education and technology in a sustainable future显示文摘Quality education is one of the pillars in the United Nations 2030 Agenda for Sustainable Development,which aims to ensure inclusive and equitable quality education and promote lifelong learning opportunities for all.This overall goal can be connected to some general trends affecting education in the information age.We argue that education is key to the future quality of human life and the sustainability of the world.Generally,education is being transformed in both formal and informal learning contexts by new digital technologies.Overall,some of these major innovations and how they are changing education can be summarized into the following aspects:1)our educational aims and objectives;2)educational ecologies and contexts of learning;3)the processes of learning;4)the processes of teaching;and 5)educational governance and policy.Meanwhile,we note some of the potential risks and downsides of these technology trends.From the sustainable perspective,our review points to a great potential for educational reform,but it can only be achieved if we are willing to rethink and even abandon some of our traditional ways of doing things in education. | Nicholas C.Burbules Guorui Fan Philip Repp | 2020 | Geography and Sustainability2020，1，2： | 3 |
| 2 | Genotype-dependent activation or repression of HBV enhancer Ⅱ by transcription factor COUP-TF1显示文摘AIM: To study the expression of HBV enhancer Ⅱ by transcription factor COUP-TF1. METHODS: In order to study the regulation of HBV variants in the vicinity of the NRRE we cloned luciferase constructs containing the HBV enhancer Ⅱ from variants and from HBV genotypes A and D and cotransfected them together with expression vectors for COUP-TF1 into HepG2 cells. RESULTS: Our fi ndings show that enhancer Ⅱ of HBV genotype A is also repressed by COUP-TF1. In contrast, two different enhancer Ⅱ constructs of HBV genotype D were activated by COUP-TF1. The activation was independent of the NRRE because a natural variant with a deletion of nt 1763-1770 was still activated by COUP- TF1. CONCLUSION: Regulation of transcription of the HBV genome seems to differ among HBV genomes derived from different genotypes. These differences in transcriptional control among HBV genotypes may be the molecular basis for differences in the clinical course among HBV genotypes. | Silke F Fischer Katja Schmidt Nicola Fiedler Dieter Glebe Christian Schüttler Jianguang Sun Wolfram H Gerlich Reinald Repp Stephan Schaefer | 2006 | World Journal of Gastroenterology2006，12，37： | 2 |
| 3 | Life cycle energy and environmental performance of a new university building: modeling challenges and design implications 显示文摘 | Scheuer C Keoleian G A Reppe P | 2003 | Energy and buildings2003，35，10： | 1 |
| 4 | Clinical significance of IgG Fc receptors and FcγR-directed immunotherapies 显示文摘 | Deo YM Graziano RF Repp R | 1997 | Immunol Today1997，18，3： | 1 |
| 5 | A point -source norovirus outbreak caused byexposure to fomites 显示文摘 | Repp KK Keene WE | 2012 | J Infect Dis2012，，16： | 1 |
| 6 | Enhanced killing of B lymphoma cells by granulocyte colony - stimulating factor - primed effector cells and Hu1D10-a humanized human 1eucocyte antigen DR antibody显示文摘 | Stockmeyer B Schiller M Repp R | 2002 | Br J Haematol2002，8，4： | 1 |
| 7 | Malignancies under cyclosporine after kidney transplantation: analysis of a 10- year period显示文摘 | Frei U Bode U Repp H | 1993 | Transplant Proc1993，25，12： | 1 |
| 8 | Lacrimal excretory system concretions:canalicular and lacrimal sac显示文摘 | Repp DJ Burkat CN Lucarelli MJ | 2009 | Ophthalmology2009，116，11： | 1 |
| 9 | Pretherapeutic identification of high risk acute myeloid leukemia (AML) patients from immunophenotypic,cytogenetic,and clinical parameters显示文摘 | VALET G REPP R LINK H et a1 | 2003 | Cytometry2003，53，1： | 1 |
| 10 | Phase 2 study of alemtuzumab (anti-CD52 monoclonal antibody) in patients with advanced mycosis fungoides/Sezary syndrome显示文摘 | Lundin J Hagberg H Repp R | 2003 | Blood2003，101，11： | 1 |
| 11 | Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CI)64 ) after in vivo application of recombinant human granulocyte colony-stimulating factor 显示文摘 | Repp R Valerius T Sendler A | 1991 | Blood1991，78，4： | 1 |
| 12 | Membrane Fas ligand actives innate immunity and terminates ocular immune privilege显示文摘 | Gregory MS Repp AC Holhbaum AM | 2002 | J Immunol2002，169，5： | 1 |
| 13 | Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone 显示文摘 | Fortunati D Reppe S Fjeldheim A | 2010 | Matrix Biology2010，29，7： | 1 |
| 14 | Docetaxel and continuous-infusion fluorouracil versus epirubicin,cisplatin,and fluorouracil for advanced gastric adenocarcinoma:a randomized phase Ⅱ study显示文摘 | Thuss-Patience PC Kretzschmar A Repp M | 2005 | Journal of Clinical Oncology:official journal of the American Society of Clinical Oncology2005，23，3： | 1 |
| 15 | Docetaxel and continuous-infusion fluorouracil veins epirubicin, cisplatin, and fluorouracil for advanced gastric adenocarcinoma: a randomized Phase II study显示文摘 | Thuss-Patience P Kretzschmaer A Repp M | 2005 | J Clin Oncol2005，23，3： | 1 |
| 16 | The addition of rituximab to a combination of fludarabine,cyclophosphamide,mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas:results of a prospective randomized study of the german low-grade lymphoma study group显示文摘 | Forstpointner R Dreyling M Repp R | 2004 | Blood2004，104，10： | 1 |
| 17 | The effect of enamel matrix derivative on gene expression in osteoblasts 显示文摘 | Reseland JE Reppe S Larsen AM | 2006 | Eur J Oral Sci2006，1141，： | 1 |
| 18 | The addition of rituximab to a combination of fludarabine,cyclophosphamide,mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas显示文摘 | Forstpointner R Drevling M Repp R | 2004 | Blood2004，104，10： | 1 |
| 19 | Docetaxel and continuous-infusion fluorouracil verus epimbicin, cisplatin and fluorouracil for advanced gastric adenocarcinoma: a randomized phase Ⅱ study显示文摘 | Thuss-Patience P Kretzschmaer A Repp M | 2005 | J Clin Oncol2005，23，3： | 1 |
| 20 | The effect of enamel matrix derivative on gene expression in osteoblastis activity 显示文摘 | Reseland JE Reppe S Larsen AM | 2006 | Eur J Oral Sci2006，114，1： | 1 |
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