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1Irreversible electroporation for the management of pancreatic cancer: Current data and future directions显示文摘Pancreatic cancer is currently the seventh leading cause of cancer death(4.5%of all cancer deaths)while 80%-90%of the patients suffer from unresectable disease at the time of diagnosis.Prognosis remains poor,with a mean survival up to 15 mo following systemic chemotherapy.Loco-regional thermal ablative techniques are rarely implemented due to the increased risk of thermal injury to the adjacent structures,which can lead to severe adverse events.Irreversible electroporation,a promising novel non-thermal ablative modality,has been recently introduced in clinical practice for the management of inoperable pancreatic cancer as a safer and more effective loco-regional treatment option.Experimental and initial clinical data are optimistic.This review will focus on the basic principles of IRE technology,currently available data,and future directions.Stavros Spiliopoulos Lazaros Reppas Dimitrios Filippiadis Antonella Delvecchio Maria Conticchio Riccar do Memeo Riccardo Inchingolo 2023World Journal of Gastroenterology2023,29,2:3
2Scalable Distributed Sensor Fault Diagnosis for Smart Buildings显示文摘The enormous energy use of the building sector and the requirements for indoor living quality that aim to improve occupants' productivity and health, prioritize Smart Buildings as an emerging technology. The Heating, Ventilation and Air-Conditioning(HVAC) system is considered one of the most critical and essential parts in buildings since it consumes the largest amount of energy and is responsible for humans comfort. Due to the intermittent operation of HVAC systems, faults are more likely to occur, possibly increasing eventually building's energy consumption and/or downgrading indoor living quality. The complexity and large scale nature of HVAC systems complicate the diagnosis of faults in a centralized framework. This paper presents a distributed intelligent fault diagnosis algorithm for detecting and isolating multiple sensor faults in large-scale HVAC systems.Modeling the HVAC system as a network of interconnected subsystems allows the design of a set of distributed sensor fault diagnosis agents capable of isolating multiple sensor faults by applying a combinatorial decision logic and diagnostic reasoning. The performance of the proposed method is investigated with respect to robustness, fault detectability and scalability. Simulations are used to illustrate the effectiveness of the proposed method in the presence of multiple sensor faults applied to a 83-zone HVAC system and to evaluate the sensitivity of the method with respect to sensor noise variance.Panayiotis M.Papadopoulos Vasso Reppa Marios M.Polycarpou Christos G.Panayiotou 2020IEEE/CAA Journal of Automatica Sinica2020,7,3:2
3Dissolutiontesting as a prognostic tool for oral drug absorption:Immediate release dosage forms显示文摘DRESSMAN J B AMIDON G L REPPAS C 1998Pharm Res1998,15,1:1
4Dissolution testing as a prognostic tool for oral drug absorption: Immediate release dosage forms 显示文摘Dressman J B Amidon G L Reppas C 1998Pharm Res1998,15,1:1
5Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy显示文摘Anette Müllertz Dimitrios G. Fatouros Maria Vertzoni Christos Reppas 2013J Pharm Pharmacol2013,,10:1
6Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery显示文摘REPPAS L B 1995Inter J Pharm1995,116,:1
7In vitro versus canine data for predicting input profiles of isosorbide-5-mononitrate from oral extended release products on a confidence interval basis显示文摘FOTAKI N SYMILLIDES M REPPAS C 2005Eur J Pharm Sci2005,24,1:1
8Accuratemultiplex polony sequencing of an evolved bacterialgenome显示文摘Shendure J Porreca GJ Reppas NB 2005Science2005,309,5741:1
9Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging显示文摘Sereno M I Dale A M Reppas J B 1995Science1995,268,5212:1
10Determination of intralumenal individual bile acids by HPLC with charged aerosol detection显示文摘Vertzoni M Archontaki H Reppas C 2008J Lipid Res2008,49,12:1
11Enhancement of cyclosporine A solubility by d-α-tocopheryl-polyethy-lene-glycol- 1000 succinate (TPGS) 显示文摘Ismailos G Reppas C Macheras P 1994Eur J Pharm Sci1994,,1:1
12Accurate multiplex polony sequencing of an evolved bacterial genome显示文摘SHENDURE J PORRECA G J REPPAS N B 2005Science2005,309,:1
13In vitro-in vivo correlations for lipophilic,poorly water-soluble drugs显示文摘Dressman JB Reppas C 2000Eur J Pharm Sci2000,11,:1
14Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging 显示文摘Sereno MI Dale AM Reppas JB 1995Science1995,268,:1
15Unusual solubility behavior of cyclosporin A in aqueous media显示文摘Ismailos G Reppas C Dressman JB 1991J Pharm Pharmacol1991,43,4:1
16Accurate multiplex polony sequencing of an evolved bacterial genome显示文摘Shendure J Porreca G J Reppas N B 2005Science2005,309,5741:1
17Accurate multiplex polony sequencing of an evolved bacterial genome显示文摘Shendure J Porreca G J Reppas N B 2005Science2005,309,5741:1
18Accurate multiplex polony sequencing of an evolved bacterial genome显示文摘Shendure J Porreca G J Reppas N B 2005Science2005,309,5741:1
19Accurate multiplex polony sequencing of an evolved bacterial genome显示文摘Shendure J Porreca G J Reppas N B 2005Science2005,309,5741:1
20Fault detection and diagnosis based on parameter set estimation显示文摘REPPA V TZES A 2011IET Control Theory and Applications2011,5,1:1
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