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| 1 | Genome-wide Targeted Mutagenesis in Rice Using the CRISPR/Cas9 System显示文摘 | Lu, Yuming Ye, Xiao Guo, Renming Huang, Jing Wang, Wei Tang, Jiuyou Tan, Longtao Zhu, Jian-kang Chu, Chengcai Qian, Yangwen | 2017 | Molecular Plant2017，10，9： | 28 |
| 2 | Cardiopulmonary,complications in chronic liver disease显示文摘有肝硬化和门静脉高血压的病人展出典型心血管、肺的血液动力学的变化。一个 vasodilatatory 状态和影响心脏、肺的功能的亢奋的动态发行量统治发行量。最近定义的肝脏硬化症的心肌症可以影响收缩、心脏舒张的功能,并且暗示机电的畸形。另外,循环 homoeostasis 的压力感受器功能和规定被损害。肺的机能障碍涉及在一些病人与肝肺症候群和 portopulmonary 高血压的发展传播畸形。最近的研究集中于血液动力学、神经元介质的 dysregulation 具有为在肝硬化的心血管、肺的复杂并发症的发展的主要重要性的断言。这个方面是重要的在这些病人的管理考虑。 | SφrenMφller JensHHenriksen | 2006 | World Journal of Gastroenterology2006，12，4： | 17 |
| 3 | miR-145 improves metabolic inflammatory disease through multiple pathways显示文摘Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes,yet the mechanisms are not completely understood.Here,we demonstrated that serum LPS levels were significantly higher in newly diagnosed diabetic patients than in normal control.miR-145 level in peripheral blood mononuclear cells decreased in type 2 diabetics.LPS repressed the transcription of miR-143/145 cluster and decreased miR-145 levels.Attenuation of miR-145 activity by anti-miR-145 triggered liver inflammation and increased serum chemokines in C57BL/6 J mice.Conversely,lentivirus-mediated miR-145 overexpression inhibited macrophage infiltration,reduced body weight,and improved glucose metabolism in db/db mice.And miR-145 overexpression markedly reduced plaque size in the aorta in ApoE−/−mice.Both OPG and KLF5 were targets of miR-145.miR-145 repressed cell proliferation and induced apoptosis partially by targeting OPG and KLF5.miR-145 also suppressed NF-κB activation by targeting OPG and KLF5.Our findings provide an association of the environment with the progress of metabolic disorders.Increasing miR-145 may be a new potential therapeutic strategy in preventing and treating metabolic diseases such as type 2 diabetes and atherosclerosis. | Min He Nan Wu Man Cheong Leong Weiwei Zhang Zi Ye Rumei Li Jinyang Huang Zhaoyun Zhang Lianxi Li Xiao Yao Wenbai Zhou Naijia Liu Zhihong Yang Xuehong Dong Yintao Li Lili Chen Qin Li Xuanchun Wang Jie Wen Xiaolong Zhao Bin Lu Yehong Yang Qinghua Wang Renming Hu | 2020 | Journal of Molecular Cell Biology2020，12，2： | 7 |
| 4 | Stability for a class of nonlinear time-delay systems via Hamiltonian functional method显示文摘This paper investigates the stability of a class of nonlinear time-delay systems via Hamiltonian functional method,and proposes a number of new results on generalized Hamiltonian realization (GHR) and stability analysis for this class of systems.Firstly,the concept of GHR of general nonlinear time-delay systems is proposed,and several new GHR methods are given.Then,based on the new GHR methods obtained,the stability of time-delay systems is investigated,and several delay-dependent sufficient conditions in term of matrix inequalities are derived for the stability analysis by constructing suitable Lyapunov-Krasovskii (L-K) functionals.Finally,an illustrative example shows that the results obtained in this paper have less conservatism,and work very well in the stability analysis of some nonlinear time-delay Hamiltonian systems. | YANG RenMing WANG YuZhen | 2012 | Science China(Information Sciences)2012，55，5： | 6 |
| 5 | L_2 DISTURBANCE ATTENUATION FOR A CLASS OF TIME-DELAY HAMILTONIAN SYSTEMS显示文摘这份报纸为时间延期的一个班考虑 L 2 骚乱变细的问题控制港口的 Hamiltonian 系统。消散的不平等被使用一条合适的控制法律和存储功能建立。然后基于 Razumikhin 稳定性定理,一个足够的条件被建议为 asymptotically 靠近环的系统的稳定性。最后,作者调查有时间不变的无常,属于某凸的围住的 polytypic 领域和 L 2 骚乱变细控制的诉讼法律被建议。有在这份报纸的介绍方法在时间延期 Hamiltonian 系统的骚乱变细工作很好的模拟表演的解说性的例子的学习。 | Weiwei SUN Yuzhen WANG Renming YANG | 2011 | Journal of Systems Science & Complexity2011，24，4： | 3 |
| 6 | Mitotic phosphorylation of PRC1 at Thr470 is required for PRC1 oligomerization and proper central spindle organization显示文摘在细胞分裂期间,染色体分离被和着丝点的锭子微导管的相互作用安排。进在分开的染色单体之间的一支组织中央锭子的 interpolarmicrotubules 的戏剧的改变为胞质分裂的开始和实行被要求。中央锭子组织要求有丝分裂的 kinesins, chromosomal 旅客蛋白质建筑群,和微导管捆绑蛋白质 PRC1。由在 Thr470 和 Thr481 的 Cdc2 的 PRC1 isphosphorylated 在有丝分裂期间。然而,在 Thr470 的功能的关联 ofPRC1 磷酸化留下了逃犯。这里,我们证明 thenon-phosphorylatable 异种 PRC1 (T470A ) 然而并非 phospho-mimicking 异种 PRC1 (T470E ) 的那表情引起中央锭子的异常组织。Immunoprecipitation 实验与野类型的 PRC1 显示那 bothPRC1 (T470A ) 和 PRC1 (T470E ) 突变蛋白质伙伴,建议 Thr470 的 thatphosphorylation 不改变 PRC1 自我协会。另外,在 vitroco 沉积,实验证明 PRC1 绑在独立于 Thr470 的 phosphorylationstate 的微导管。胶化过滤实验建议了 PRC1 的 Thr470 promotesoligomerization 的那磷酸化。给 Thr470 磷酸化的那预防禁止 PRC1oligomerization 试管内并且引起中央锭子体内的一个异常组织的事实,我们建议这 phosphorylation 依赖的 PRC1 oligomerization 保证中央锭子汇编在房间周期发生在适当时间。 | Chuanhai Fu Feng Yan Fang Wu Quan Wu Joseph Whittaker Haiying Hu Renming Hu Xuebiao Yao | 2007 | Cell Research2007，17，5： | 3 |
| 7 | L log L criterion for a class of multitype superdiffusions with non-local branching mechanisms显示文摘In this paper, we provide a pathwise spine decomposition for multitype superdiffusions with nonlocal branching mechanisms under a martingale change of measure. As an application of this decomposition,we obtain a necessary and sufficient condition(called the L log L criterion) for the limit of the fundamental martingale to be non-degenerate. This result complements the related results obtained in Kyprianou et al.(2012),Kyprianou and Murillo-Salas(2013) and Liu et al.(2009) for superprocesses with purely local branching mechanisms and in Kyprianou and Palau(2018) for super Markov chains. | Zhen-Qing Chen Yan-Xia Ren Renming Song | 2019 | Science China Mathematics2019，62，8： | 3 |
| 8 | A CFD model for predicting the heat transfer in the industrial scale packed bed显示文摘Compared to the traditional lumped-parameter model, computational fluid dynamics(CFD) attracted more attentions due to facilitating more accurate reactor design and optimization methods when analyzing the heat transfer in the industrial packed bed. Here, a model was developed based on the CFD theory, in which the heterogeneous fluid flow was resolved by considering the oscillatory behavior of voidage and the effective fluid viscosity. The energy transports in packed bed were calculated by the convection and diffusion incorporated with gaseous dispersion in fluid and the contacting thermal conductivity of packed particles in solids. The heat transfer coefficient between fluid and wall was evaluated by considering the turbulence due to the packed particles adjacent to the wall. Thus, the heat transfer in packed bed can be predicted without using any adjustable semi-empirical effective thermal conductivity coefficient. The experimental results from the literature were employed to validate this model. | Baolin Hou Renming Ye Yanqiang Huang Xiaodong Wang Tao Zhang | 2018 | Chinese Journal of Chemical Engineering2018，26，2： | 2 |
| 9 | Synthesis and combined properties of novel fluorinated cationic surfactants derived from hexafluoropropylene dimer显示文摘Three novel fluorinated cationic surfactants were prepared by adopting perfluoro-2-methyl-2-pentene as raw substrate. The as-obtained fluorinated cationic surfactants exhibited excellent surface properties, all of them can reduce the surface tension of water to below 20.00 mN/m at the critical micelle concentrations(CMC). The incorporation of SDS, AOS, APG or LAB into 2-(4-(3,3,4,4,5,5,5-heptafluoro-2,2-bis(trifluoromethyl)pentyl)benzamido)-N,N-dimethylethana-mine oxide 4 a could generate much lower CMC and surface tension value at the CMC than individual 4 a. Especially, the surface tension values of that combined APG/4 a can be reduced to 17.31 mN/m. The excellent surface activities and their remarkable compatibility to various types of hydrocarbon surfactants make them as sustainable alternatives to PFOA(perfluorooctanoic acid, C_7 F_(15)CO_2 H) and PFOS(perfluorooctane sulphonate,C_8 F_(17)SO_3 X, with X = K, Na, H). | Chao Lin Renming Pan Ping Xing Biao Jiang | 2018 | Chinese Chemical Letters2018，29，11： | 2 |
| 10 | Effects of berberine on glucose metabolism in vitro显示文摘 | Jun Yin Renming Hu Mingdao Chen Jinfeng Tang Fengying Li Ying Yang Jialun Chen | 2002 | Metabolism2002，，11： | 2 |
| 11 | Uniform boundary Harnack principle for rotationally symmetric Lvy processes in general open sets显示文摘In this paper we prove the uniform boundary Harnack principle in general open sets for harmonic functions with respect to a large class of rotationally symmetric purely discontinuous Lvy processes. | KIM Panki SONG RenMing VONDRACEK Zoran | 2012 | Science China Mathematics2012，55，11： | 2 |
| 12 | Sources of particulate organic matter in the Chukchi and Siberian shelves: clues from carbon and nitrogen isotopes显示文摘The stable isotopic composition(δ13C andδ15N)and carbon/nitrogen ratio(C/N)of particulate organic matter(POM)in the Chukchi and East Siberian shelves from July to September,2016 were measured to evaluate the spatial variability and origin of POM.Theδ13CPOC values were in the range of−29.5‰to−17.5‰with an average of−25.9‰±2.0‰,and theδ15NPN values ranged from 3.9‰to 13.1‰with an average of 8.0‰±1.6‰.The C/N ratios in the East Siberian shelf were generally higher than those in the Chukchi shelf,while theδ13C andδ15N values were just the opposite.Abnormally low C/N ratios(<4),lowδ13CPOC(almost−28‰)and highδ15NPN(>10‰)values were observed in the Wrangel Island polynya,which was attributed to the early bloom of small phytoplankton.The contributions of terrestrial POM,bloom-produced POM and non-bloom marine POM were estimated using a three end-member mixing model.The spatial distribution of terrestrial POM showed a high fraction in the East Siberian shelf and decreased eastward,indicating the influence of Russian rivers.The distribution of non-bloom marine POM showed a high fraction in the Chukchi shelf with the highest fraction occurring in the Bering Strait and decreased westward,suggesting the stimulation of biological production by the Pacific inflow in the Chukchi shelf.The fractions of bloom-produced POM were highest in the winter polynya and gradually decreased toward the periphery.A negative relationship between the bloom-produced POM and the sea ice meltwater inventory was observed,indicating that the net sea ice loss promotes early bloom in the polynya.Given the high fraction of bloom-produced POM,the early bloom of phytoplankton in the polynyas may play an important role on marine production and POM export in the Arctic shelves. | Renming Jia Xinyue Mu Min Chen Jing Zhu Bo Wang Xiaopeng Li A S Astakhov Minfang Zheng Yusheng Qiu | 2020 | Acta Oceanologica Sinica2020，39，9： | 2 |
| 13 | EMC10 governs male fertility via maintaining sperm ion balance显示文摘Infertility is a severe public health problem worldwide that prevails up to 15% in reproductive-age couples,and male infertility accounts for half of total infertility.Studies on genetically modified animal models have identifed lots of genes involved in the pathogenesis of male infertility.The underlying causes,however,remain largely unclear.In this study,we provide evidence that EMCIO,one subunit of endoplasmic reticulum (ER)membrane protein complex (EMC),is required for male fertility.EMC10 is significantly decreased in spermatozoa from patients with asthenozoospermia and positively associated with human sperm motility. Male mice lacking Emc10 gene are completely sterile.Emc10-null spermatozoa exhibit multiple defects including abnormal morphology,decreased motility,impaired capacitation,and impotency of acrosome reaction,thereby which are incapable of fertilizing intact or ZP-free oocytes.However,intracytoplasmic sperm injection could rescue this defect caused by EMC10 deletion. Mechanistically,EMC10 deficiency leads to inactivation of Na/K-ATPase,in turn giving rise to an increased level of intraceltutar Na^+ in spermatozoa,which contributes to decreased sperm motility and abnormal morphology.Other mechanistic investigations demonstrate that the absence of EMC10 results in a reduction of HCO3^- entry and subsequent decreases of both cAMP-dependent protein kinase A substrate phosphorylation and protein tyrosine phosphorytation.These data demonstrate that EMC10 is indispensable to mate fertility via maintaining sperm ion balance of Na^+ and HCO3^-,and also suggest that EMC10 is a promising biomarker for male fertility and a potential pharmaceutical target to treat male infertility. | Yuchuan Zhou Fei Wu Man Zhang Zuquan Xiong Qianqian Yin Yanfei Ru Huijuan Shi Jinsong Li Shanhua Mao Yanliang Li Xinyi Cao Renming Hu Chong Wee Liew Qiang Ding Xuanchun Wang Yonglian Zhang | 2018 | Journal of Molecular Cell Biology2018，10，6： | 2 |
| 14 | The influencing factors of HEAE burning rate and fire suppression efficiency 显示文摘 | By Zhang Yongfeng Liao Guangxuan Pan Renming Wang Hua | 2006 | Journal of Chemical Health &Safety2006，，9： | 1 |
| 15 | A Predicted Milling Force Model for High-speed End Milling Operation 显示文摘 | Fuh Kuang-hua Hwang Renming | 1997 | International Journal of Machine Tools & Manufacture1997，37，7： | 1 |
| 16 | All-Solid-State Thin-Film Lithium-Sulfur Batteries显示文摘Lithium-sulfur(Li-S)system coupled with thin-film solid electrolyte as a novel high-energy micro-battery has enormous potential for complementing embedded energy harvesters to enable the autonomy of the Internet of Things microdevice.However,the volatility in high vacuum and intrinsic sluggish kinetics of S hinder researchers from empirically integrating it into allsolid-state thin-film batteries,leading to inexperience in fabricating all-solid-state thin-film Li-S batteries(TFLSBs).Herein,for the first time,TFLSBs have been successfully constructed by stacking vertical graphene nanosheets-Li2S(VGsLi2S)composite thin-film cathode,lithium-phosphorous-oxynitride(LiPON)thin-film solid electrolyte,and Li metal anode.Fundamentally eliminating Lipolysulfide shuttle effect and maintaining a stable VGs-Li2S/LiPON interface upon prolonged cycles have been well identified by employing the solid-state Li-S system with an“unlimited Li”reservoir,which exhibits excellent longterm cycling stability with a capacity retention of 81%for 3,000 cycles,and an exceptional high temperature tolerance up to 60℃.More impressively,VGs-Li2S-based TFLSBs with evaporated-Li thin-film anode also demonstrate outstanding cycling performance over 500 cycles with a high Coulombic efficiency of 99.71%.Collectively,this study presents a new development strategy for secure and high-performance rechargeable all-solid-state thin-film batteries. | Renming Deng Bingyuan Ke Yonghui Xie Shoulin Cheng Congcong Zhang Hong Zhang Bingan Lu Xinghui Wang | 2023 | Nano-Micro Letters2023，15，5： | 1 |
| 17 | Investigation of CF carbene on the sur- face of activated charcoal in the synthesis of trifluoroiodomethane via vapor-phase catalytic reaction显示文摘 | YANG Guangcheng SHI Lei PAN Renming | 2009 | Journal of Fluorine Chemistry2009，130，2： | 1 |
| 18 | The clinical feasibility and effect of online cone beam computer tomography-guided intensity-modulated radiotherapy for nasopharyngeal cancer显示文摘 | Jin Wang Sen Bai Nianyong Chen Feng Xu Xiaoqin Jiang Yan Li Qingfeng Xu Yali Shen Hong Zhang Youling Gong Renming Zhong Qingfeng Jiang | 2008 | Radiotherapy and Oncology2008，，： | 1 |
| 19 | Detection of intrafractional tumour position error in radiotherapy utilizing cone beam computed tomography显示文摘 | Feng Xu Jin Wang Sen Bai Yan Li Yali Shen Renming Zhong Xiaoqin Jiang Qingfeng Xu | 2008 | Radiotherapy and Oncology2008，，： | 1 |
| 20 | The crystal structure and VUV luminescent properties of the rare earth borates [J]显示文摘 | YangZ RenM LinJH etal | | 高等学校化学学报0，，： | 1 |
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