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| 1 | Dissection of genetic overlap of salt tolerance QTLs at the seedling and tillering stages using backcross introgression lines in rice显示文摘QTLs for salt-tolerance(ST)related traits at the seedling and tillering stages were identified using 99 BC2F8 introgression lines(IL)derived from a cross between IR64(indica)as a recurrent parent and Binam(japonica)from Iran as the donor parent.Thirteen QTLs affecting survival days of seedlings(SDS), score of salt toxicity of leaves(SST),shoot K + concentration(SKC)and shoot Na + concentration(SNC) at the seedling stage and 22 QTLs underlying fresh weight of shoots(FW),tiller number per plant(TN) and plant height(PH)at the tillering stage were identified.Most QTLs detected at the tillering stage showed obvious differential expression to salt stress and were classified into three types based on their differential behaviors.Type I included 11 QTLs which were expressed only under the non-stress condition.Type II included five QTLs expressed in the control and the salt stress conditions,and three of them(QPh5,QPh8 and QTn9)had similar quantity and the same direction of gene effect,suggesting their expression was less influenced by salt stress.Type III included six QTLs which were detectable only under salt stress,suggesting that these QTLs were apparently induced by the stress.Thirteen QTLs affecting trait difference or trait stability of ILs between the stress and non-stress conditions were identified and the Binam alleles at all loci except QPh4,QTn2 and QFw2a decreased trait difference.The three QTLs less influenced by the stress and 13 QTLs affecting trait stability were considered as ST QTLs which contributed to ST.Comparing the distribution of QTLs detected at the seedling and tillering stages,most(69%)of them were genetically independent.Only four were the same or adjacent regions on chromosomes 1,2,8 and 11 harboring ST QTLs detected at the two stages,suggesting that partial genetic overlap of ST across the two stages occurs.It is likely,therefore,to develop ST rice variety for both stages by pyramiding of ST QTLs of different stages or selection against the overlapping QTLs between the two stages via marker-assisted selection(MAS). | ZANG JinPing 1 ,SUN Yong 1 ,WANG Yun 1 ,YANG Jing 1 ,LI Fang 1 ,ZHOU YongLi 1 ,ZHU LingHua 1 , Reys JESSICA2,Fotokian MOHAMMADHOSEIN 2,XU JianLong 1&LI ZhiKang 1,2 1Institute of Crop Sciences/National Key Facility for Crop Gene Resources&Genetic Improvement,Chinese Academy of Agricul- tural Sciences,Beijing 100081,China 2International Rice Research Institute,DAPO Box 7777,Metro Manila,Philippines | 2008 | Science China(Life Sciences)2008,51,7: | 32 |
| 2 | Effects of imidapril on heterogeneity of action potential and calcium current of ventriclar myocytes in infarcted rabbits显示文摘AIM: To investigate the effects of chronic treatment with imidapril on the electrophysiologic heterogeneous change of the noninfarcted myocardium of rabbits after myocardial infarction and the mechanism of its antiarrhythmic efficacy. METHODS: Rabbits with left coronary artery ligation were prepared and allowed to recover for 8 weeks. Myocytes were isolated from subendocardial, midmyocardial, and subepicardial regions of the noninfarcted left ventricular wall. Action potentials and calcium current were recorded using whole-cell patch clamp technique. RESULTS: The action potential duration of repolarization 90 % (APD90) was more prolonged in midmyocardium rather than in subepicardium and subendocardium with healed myocardial infarction. The transmural dispersion of repolarization (TDR) was increased in the three ventricular regions. The amplitude of/Ca-L was enhanced but its density was decreased in noninfarcted ventricular myocytes due to increased cell membrane capacitance. The increased differences of calcium currents among subepicardium, midmyocardium, and subendocardium were also discovered. Normalization of heterogeneous changes in repolarization after treatment with imidapril was observed and decrease of TDR in noninfarcted area was measured. Early after depolarization (EAD) events of noninfarcted midmyocardium were markedly decreased by imidapril. CONCLUSION: Imidapril reduced the electrophysiologic heterogeneities in noninfarcted area in rabbits after myocardial infarction. This ability of imidapril may contribute to its antiarrhythmic efficacy. | Yang LI, Qiao XUE, Jie MA, Cun-tai ZHANG, Ping QIU, Lin WANG Wei GAO ,Rei CHENG,Zai-ying LU, Shi-wen WANGInstitute of Geriatric Cardiology of Chinese PLA General Hospital, Beijing 100085, China Department of Cardiology, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China | 2004 | Acta Pharmacologica Sinica2004,25,11: | 7 |
| 3 | Accelerated flap prefabrication with vascular endothelial growth factor 显示文摘 | Li QF Reis ED Zhang WX | 2000 | J Reconstr Microsurg2000,16,: | 1 |
| 4 | Changes in microstructure and physico-chemical properties of hydroxyapatite-silk fibroin nanocomposite with varying silk fibroin content显示文摘 | LI Wang REI Nemoto MAMORU Senna | 2004 | Journal of the European Ceramic Society2004,24,: | 1 |
| 5 | Elevating high-density lipoprotein cholesterol in apoliprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content显示文摘 | Rong JX Li J Reis ED | 2001 | Circulation2001,104,: | 1 |
| 6 | Towards design principles for optimal transport networks显示文摘 | Li G Reis S D S M oreira A A | 2010 | PRL2010,104,01: | 1 |
| 7 | Accelerated flap prefabrication with vascular endothelial growth factor显示文摘 | Li QF Reis ED Zhang WX etal | 2000 | J Reconstr Micro surg2000,16,: | 1 |
| 8 | Elveating high-density lipoprotein cholesterol in apolipoprotein-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content显示文摘 | Rong JX Li J Reis ED | 2001 | Circulation2001,104,: | 1 |
| 9 | Accelerated flap pre- fabrication with vascular endothelial growth factor显示文摘 | Li Q F Reis E D Zhang W X | 2000 | J Reconstr Microsurg2000,16,1: | 1 |
| 10 | Accelerated flap prefabrication with vascular endothelial growth factor显示文摘 | Li QF Reis ED Zhang WX | 2000 | J Reconstr Microsurg2000,16,1: | 1 |
| 11 | Accelerated flap prefabrication with vascular endothelial growth factor显示文摘 | Li QF Reis ED Zhang WX | 2000 | J Reconstr Microsurg2000,16,1: | 1 |
| 12 | Elveating high-density lipoprotein cholesterol inapolipoprotein E-def iciest mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content显示文摘 | Rong JX Li J Reis ED | 2001 | Circulation2001,104,: | 1 |
| 13 | Accelerated flap prefabrication with vascular endothelial growth factor显示文摘 | Li QF Reis ED Zhang WX | 2000 | J Reconstr Microsurg2000,16,: | 1 |
| 14 | Accelerated flap prefabrication with vascular endothelial growth factor显示文摘 | REIS ED ZHANG WX | 2000 | J Reconstr Microsurg2000,16,: | 1 |
| 15 | Elevating high -density lipoprotein choles- terol in apolipoprotein E - deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell con-tent显示文摘 | Rong JX Li J Reis ED | 2001 | Circulation2001,104,4: | 1 |
| 16 | Elevating high-density lipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content显示文摘 | Rong JX Li J Reis ED | 2001 | Circulation2001,104,4: | 1 |
| 17 | Towards Design Principles for Optimal Transport Networks显示文摘 | Li G Reis S D S Moreira A A | 2010 | Physical Review Letters2010,,: | 1 |
| 18 | Optimal transport exponent in spatially embedded networks显示文摘 | Li G Reis S D S Moreira A A | 2013 | Physical Review E2013,,: | 1 |
| 19 | Strontium-substituted apatite coating grown on Ti6Al4V substrate through biomimetic synthesis显示文摘 | Oliveira AL Reis RL Li P | | 0,,01: | 1 |
| 20 | Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content显示文摘 | Rong JX Li J Reis ED | 2001 | Circulation2001,104,: | 1 |