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	题名	作者	年代	出处	被引量
1	BCLC策略:预后预测和治疗推荐2022版更新显示文摘2018版BCLC预后和治疗推荐策略发布后,肝细胞癌(简称HCC)的研究又取得了重大进展。本次更新基于肝癌各领域的研究进展结果。重点关注影响策略的重要研究进展。虽然近年的研究结果成绩斐然,但将其引入为临床医生和研究者提供行动依据的循证模型指南来说证据效力依然不够确切。本文对该问题进行分析,阐述了为HCC患者制定个体化治疗临床决策所需的批判性思维和专业知识。	Reig M Forner A Rimola J Ferrer-Fabrega J Burrel M Garcia-Criado A Kelley RK Galle PR Mazzaferro V Salem R Sangro B Singal AG Vogel A Fuster J Ayuso C Bruix J 刘永凡(摘译) 崔笑(摘译) 耿小平(审校)	2022	肝胆外科杂志2022，30，5：	80
2	Current Strategy for Staging and Treatment: The BCLC Update and Future Prospects显示文摘	Alejandro Forner María E. Reig Carlos Rodriguez de Lope Jordi Bruix	2010	Semin Liver Dis2010，，01：	5
3	Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.	Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel	2014	World Journal of Gastroenterology2014，20，42：	5
4	Management of HCC显示文摘	Carlos Rodríguez de Lope Silvia Tremosini Alejandro Forner María Reig Jordi Bruix	2012	Journal of Hepatology2012，，：	5
5	Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisation (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design显示文摘	Marta Burrel María Reig Alejandro Forner Marta Barrufet Carlos Rodríguez de Lope Silvia Tremosini Carmen Ayuso Josep M Llovet María Isabel Real Jordi Bruix	2012	Journal of Hepatology2012，，6：	3
6	Management of HCC显示文摘	Carlos Rodríguez de Lope Silvia Tremosini Alejandro Forner María Reig Jordi Bruix	2012	Journal of Hepatology2012，，：	2
7	Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisation (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design显示文摘	Marta Burrel María Reig Alejandro Forner Marta Barrufet Carlos Rodríguez de Lope Silvia Tremosini Carmen Ayuso Josep M Llovet María Isabel Real Jordi Bruix	2012	Journal of Hepatology2012，，6：	1
8	Assessing farming eco - efficiency: A Data EnvelopmentAnalysis 显示文摘	Picazo - Tadeo A J Gomez - Limon J A Reig - MartinezE	2011	Journal of Environmental Management2011，，92：	1
9	Construction and validation of a specific quality of life instrument for adolescents with spine deformities显示文摘	Climent JM Reig A Snchez J	1995	Spine1995，20，18：	1
10	Calibration transfer in chemiluminescence analysis application to chromium determination by luminol-hydrogen peroxide reaction显示文摘	TORTAJADA L A FALCO P C REIG F B	2001	Analytica Chimica Acta2001，446，：	1
11	α-Fetoprotein for Hepatocellular Carcinoma Diagnosis: The Demise of a Brilliant Star显示文摘	Alejandro Forner María Reig Jordi Bruix	2009	Gastroenterology2009，，1：	1
12	Effectiveness and safety of prehospital urapidil for hypertensive emergencies显示文摘	Reig A J Farre B I Frances C F	2001	Am J Emerg Med2001，19，2：	1
13	A point mutation in the RDS-peripherin gene in a Spanish family with central areolar choroidal dystrophy显示文摘	Serra A Gean E	1995	Ophthalmic Genet1995，16，2：	1
14	Trochanteric gamma nail and compression hip screw for trochanteric fractures:a randomized,prospective,comparative study in 210 elderly patients with a new design of the gamma nail显示文摘	Utrilla A L Reig J S Munoz F M	2005	J Orthop Trauma2005，19，4：	1
15	Neu- roendocrine small cell carcinoma of the uterine cervix 显示文摘	Reig Castillejo A Membrive Conejo I Foro Arnalot P	2010	Clin Transl Oncol2010，12，7：	1
16	Portal hypertension and the outcome of surgery for hepatocellular carcinoma in compensated cirrhosis:A systematic review and meta-analysis显示文摘	Berzigotti A Reig M Abraldes JG	2015	Hepatology2015，61，2：	1
17	Alpha-fetoprotein for hepatocellular carcinoma diagnosis:the desmise of a brilliant star显示文摘	FORNER A REIG M BRUIX J	2009	Gastroenterology2009，137，1：	1
18	Sustained release of liposome-encapsulated enrofloxacin after intramuscular administration in rabbits显示文摘	Cabanes A Reig F Anton J M	1995	AM J Vet Res1995，56，11：	1
19	Outsoucing and efficiency: the case of spanish citrus farming显示文摘	PICAZO-TADEO A REIG M E	2006	Agricultural Economics2006，35，21：	1
20	Alpha -fetoprotein for hepa- tocellular carcinoma diagnosis; the demise of a brilliant star 显示文摘	FORNER A REIG M BRUIX J	2009	Gastroenterology2009，137，1：	1

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