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| 1 | 射血分数正常心力衰竭的患病率和临床结局的变化趋势显示文摘Background: The prevalence of heart failure with preserved ejection fraction may be changing as a result of changes in population demographics and in the prevalence and treatment of risk factors for heart failure. Changes in the prevalence of heart failure with preserved ejection fraction may contribute to changes in the natural history of heart failure. We performed a study to define secular trends in the prevalence of heart failure with preserved ejection fraction among patients at a single institution over a 15-year period. Methods: We studied all consecutive patients hospitalized with decompensated heart failure at Mayo Clinic Hospitals in Olmsted County, Minnesota, from 1987 through 2001. We classified patients as having either preserved or reduced ejection fraction. The patients were also classified as community patients(Olmsted County residents) or referral patients. Secular trends in the type of heart failure, associated cardiovascular disease, and survival were defined. Results: A total of 6076 patients with heart failure were discharged over the 15-year period; data on ejection fraction were available for 4596 of these patients(76 percent). Of these, 53 percent had a reduced ejection fraction and 47 percent had a preserved ejection fraction. The proportion of patients with the diagnosis of heart failure with preserved ejection fraction increased over time and was significantly higher among community patients than among referral patients(55 percent vs. 45 percent). The prevalence rates of hypertension, atrial fibrillation, and diabetes among patients with heart failure increased significantly over time. Survival was slightly better among patients with preserved ejection fraction(adjusted hazard ratio for death, 0.96; P=0.01). Survival improved over time for those with reduced ejection fraction but not for those with preserved ejection fraction. Conclusions: The prevalence of heart failure with preserved ejection fraction increased over a 15-year period, while the rate of death from this disorder remained unchanged. These trends underscore the importance of this growing public health problem. | Owan T.E. Hodge D.O. Herges R.M. M.M. Redfield 马超 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，，12： | 11 |
| 2 | The natriuretic peptides in cardiovascular medicine显示文摘 | Munagala VK Burnett JC Redfield MM | 2004 | Curr Probl cardiol2004，29，12： | 2 |
| 3 | Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide in the general community:determinants and detection of left ventricular dysfunction显示文摘 | Costello-Boerrigter LC Boerrigter G Redfield MM | 2006 | J Am Coll Cardiol2006，47，2： | 1 |
| 4 | Trends in heart failure incidence and survival in a community-based population显示文摘 | ROGER V L WESTON S A REDFIELD M M | 2004 | JAMA2004，292，3： | 1 |
| 5 | Effects of adjuvants and multiple antigen peptides on humoral and cellular immune responses to gp 160 of HIV-1显示文摘 | Levi M Ruden U Redfield R | 1993 | J Aequir Immane Defic Syndr1993，6，： | 1 |
| 6 | Congestive Heart Failure in the Community: A Study of All Incident Cases in Olmsted County, Minnesota, in 1991显示文摘 | Michele Senni Christophe M. Tribouilloy Richard J. Rodeheffer Steven J. Jacobsen Jonathan M. Evans Kent R. Bailey Margaret M. Redfield | 1998 | Circulation1998，，21： | 1 |
| 7 | The biological control of chemical factors in the environment显示文摘 | REDFIELD A C | 1958 | American Scientist1958，46，： | 1 |
| 8 | The Ablate and Pace Trial: A Prospective Study of Catheter Ablation of the AV Conduction System and Permanent Pacemaker Implantation for Treatment of Atrial Fibrillation显示文摘 | G. Neal Kay Kenneth A. Ellenbogen Michael Giudici Margaret M. Redfield Louise S. Jenkins Marcus Mianulli Bruce Wilkoff | 1998 | Journal of Interventional Cardiac Electrophysiology1998，，2： | 1 |
| 9 | Trends in heart failureincidence and survival in a community based population显示文摘 | Roger VL Weston SA Redfield MM | 2004 | JA- MA2004，292，： | 1 |
| 10 | Experimental characterization of a UWB channel for body area networks显示文摘 | Xia Ling-li Redfield S Chiang P | 2011 | EURASIP Journal on Wireless Communications and Networking2011，2011，： | 1 |
| 11 | Epidemiology of diastolid heart failure 显示文摘 | Owan TE Redfield MM | 2005 | Prog Cardiovasc Dis2005，47，5： | 1 |
| 12 | ,The biological control of chemical factors in the environment显示文摘 | | 1958 | American Science1958，46，： | 1 |
| 13 | Memorandum on the study of acculturation显示文摘 | Redfield R Linton R Herskovits M J | 1936 | American Anthropologist1936，，38： | 1 |
| 14 | Plasma brain natriuretic peptide concentration: impact of age and gender显示文摘 | Redfield MM Rodeheffer RJ Jacobsen SJ | 2002 | J Am Coll Cardiol2002，40，5： | 1 |
| 15 | Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide in the general community: determinants and detection of left ventricular dysfunction显示文摘 | Costello-Boerrigter LC Boerrigter G Redfield MM | 2006 | Am Coll Cardiol2006，47，2： | 1 |
| 16 | The biological control of chemical factors in the environment显示文摘 | Redfield A C | 1958 | American Science1958，，46： | 1 |
| 17 | Sildenafil and B-Type Natriuretic Peptide Acutely Phosphorylate Titin and Improve Diastolic Distensibility In Vivo显示文摘 | Kalkidan Bishu Nazha Hamdani Selma F. Mohammed Martina Kruger Tomohito Ohtani Ozgur Ogut Frank V. Brozovich John C. Burnett Wolfgang A. Linke Margaret M. Redfield | 2011 | Circulation2011，，25： | 1 |
| 18 | On the theory of relaxation processes显示文摘 | Redfield A G | | 0，，01： | 1 |
| 19 | Plasma brain natriuretic peptide concentration; impact of age and gender显示文摘 | Redfield M M Rodeheffer R J Jacobsen S J | 2002 | J Am Coll Cardiol2002，40，5： | 1 |
| 20 | Atrial fibrillation and ven- tricular dysfunction: a vicious electromechanical cycle显示文摘 | Cha Y M Redfield M M Shen W K et aI | 2004 | Circu- lation2004，109，23： | 1 |
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