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| 1 | Platelet-to-lymphocyte ratio in the setting of liver transplantation for hepatocellular cancer: A systematic review and meta-analysis显示文摘AIM To perform a systematic review and meta-analysis on platelet-to-lymphocyte ratio(PLR) as a risk factor for post-transplant hepatocellular cancer(HCC) recurrence. METHODS A systematic literature search was performed using PubM ed. Participants of any age and sex, who underwent liver transplantation for HCC were considered following these criteria:(1) studies comparing pre-transplant low vs high PLR values;(2) studies reporting post-transplant recurrence rates; and(3) if more than one study was reported by the same institute, only the most recent was included. The primary outcome measure was set for HCC recurrence after transplantation. RESULTS A total of 5 articles, published between 2014 and 2017, fulfilled the selection criteria. As for the quality of the reported studies, all the investigated articles presented an overall high quality. A total of 899 cases were investigated: 718 cases(80.0%) were males. Three studies coming from European countries and one from Japan presented HCV as the main cause of cirrhosis. On the opposite, one Chinese study presented a greater incidence of HBV-related cirrhotic cases. In all the studies apart one, the PLR cut-off value of 150 was reported. At meta-analysis, high PLR value was associated with a significant increase in recurrence after transplantation(OR = 3.33; 95%CI: 1.78-6.25; P < 0.001). A moderate heterogeneity was observed among the identified studies according to the Higgins I^2 statistic value.CONCLUSION Pre-transplant high PLR values are connected with an increased risk of post-operative recurrence of hepatocellular cancer. More studies are needed for better clarify the biological mechanisms of this results. | Quirino Lai Fabio Melandro Zoe Larghi Laureiro Francesco Giovanardi Stefano Ginanni Corradini Flaminia Ferri Redan Hassan Massimo Rossi Gianluca Mennini | 2018 | World Journal of Gastroenterology2018，24，15： | 19 |
| 2 | More than Network Structure: How Knowl- edge Heterogeneity Influences Managerial Performance and Innovative- ness 显示文摘 | Redan S Galunic D C | 2004 | Strategic Management Journal2004，25，： | 1 |
| 3 | Assessment and management of patients with wound - related pain 显示文摘 | Redan A Sturman E | 2009 | Nurs stand2009，23，54： | 1 |
| 4 | Protect the ureters显示文摘 | Redan JA McCarus SD | 2009 | JSIS2009，13，2： | 1 |
| 5 | Global variation in copy number in the human genome显示文摘 | Redan R Ishikawa S Fitch K R | 2006 | Nature2006，444，7118： | 1 |
| 6 | Extraperitoneal endometriosis with catamenial pneumothoraces:a review of the literature显示文摘 | Robcrts LM Redan J Reich H | | 0，，04： | 1 |
| 7 | Influence of Glomus intraradices on Cd partitioning in a pot experiment with Medicago truncatula in four contaminated soils 显示文摘 | Redan P O Baguiristain T Leyval C | 2008 | Soil Biol Biochem2008，40，： | 1 |
| 8 | Mechanisms of hyper- tension in the cardiometabolic syndrome 显示文摘 | Redan J Cifkova R Laurent S | 2009 | J Hypertens2009，27，3： | 1 |
| 9 | Antioxidant activities and oxida- tive stress byproducts in human hypertension 显示文摘 | Redan J Oliva MR Tormos C | 2003 | Hypertension2003，41，5： | 1 |
| 10 | Early after-depolarizations and torsade de pointes:implicationsfor the control of cardiac arrhythmias by prolonging repolar ization显示文摘 | Redan DM | 1993 | Eur Heart J1993，14，： | 1 |
| 11 | Effects of low potassium or magnesiumeon centrations on isolated cardiac tissue显示文摘 | Redan DM lansmith DH | 1987 | Am J Med1987，82，： | 1 |
| 12 | Lidocaine-prilocaine EMLA (R) cream as analgesia in hysteroscopy practice: a prospective, randomized, non-blinded, controlled study显示文摘 | Arnan B Jovell E Redan S | 2013 | Acta Obstetricia Et Gynecologica Scandinavica2013，92，8： | 1 |
| 13 | Efficacy of combina- tion therapy with angiotensin -converting enzyme inhibitor and calcium channel blocker in hypertension 显示文摘 | Redan J Trenkwalder P R Barrios V | 2013 | Expert Opin Pharmacother2013，14，2： | 1 |
| 14 | Organ distribution of gut-derived bacteria caused by bowel manipulation or ischemia 显示文摘 | Redan JA Rush BF Jr Lysz TW | 1990 | Am J Surg1990，1590，： | 1 |
| 15 | Diagnostic laparoscopy and adhesiolysis :does it help with complex abdominal and pelvic pain syndrome (capps) in general surgery 显示文摘 | McClain GD Redan JA McCarus SD | 2011 | JSLS2011，15，1： | 1 |
| 16 | More than network structure: how knowledge heterogeneity influeneesmanagerial performance and innovativeness 显示文摘 | Redan S Galunic C | 2004 | Strategic Management Journal2004，，25： | 1 |
| 17 | Organ distribution of gutderived bacteria caused by bowel manipulation or ischemia显示文摘 | Redan JA Rush BF Lysz TW | 1990 | Am J Surg1990，159，1： | 1 |
| 18 | The effect of elevated CO2 on growth and pho- tosynthesis of two Eucalyptus species exposed to hight temperatures and water defieits 显示文摘 | Redan J S Ball M C | 1996 | Plant Physiol1996，111，3： | 1 |
| 19 | Diagnostic laparosco- py and adhesiolysis: does it help with complex abdominal and pelvic pain syndrome (capps) in general surgery? 显示文摘 | McClaln GD Redan JA McCarus SD | 2011 | JSLS2011，15，1： | 1 |
| 20 | ESH position paper: renal denerva- tion-an interventional therapy of resistant hypertension 显示文摘 | Schmieder RE Redan J Grassi G | 2012 | J Hypertens2012，30，： | 1 |
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