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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Cubic to orthorhmbic difusionless phase change-experimentaland theoretical studies of aucd显示文摘 | Lieberman D S Wechsler M S Read T A | 1955 | J Applied Physics1955，26，： | 2 |
| 3 | Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells显示文摘 | Read M A Cordle S R Veach R A | 1993 | Proc Natl Acad Sci U S A1993，90，21： | 2 |
| 4 | The observation of the non-cova-lent interactions in solution by electrospray ionization massspectrometry: promise, pitfalls and prognosis显示文摘 | Read S M Currier G Bacic A | 1996 | Carbohydr Res1996，281，： | 1 |
| 5 | Using the theory of planned behaviour to investigate the determinants of recycling behaviour:a case study from Brixworth,UK显示文摘 | Tonglet M Phillips P S Read A D | | 0，，41： | 1 |
| 6 | Correction of the bleeding time with lyophilized platelet infusions in dogs on cardiopulmonary bypass 显示文摘 | BODE A P LUST R M READ M S | 2008 | Clin Appl Thromb Hemost2008，14，： | 1 |
| 7 | Forces on oscillating foils for propulsion and maneuver- ing显示文摘 | READ D A HOVER F S TRIANTAFYLLOU M S | 2003 | Journal of Fluids and Structure2003，17，1： | 1 |
| 8 | Chronic dipeptidyl peptidase-4 inhibition with sitagliptin is associated with sustained protection against ischemic left ventricular dysfunction in a pilot study of patients with type 2 diabetes mellitus and coronary artery disease显示文摘 | McCormick L M Kydd A C Read P A | 2014 | Circ Cardiovasc Imaging2014，7，2： | 1 |
| 9 | NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation显示文摘 | READ M A WHITLEY M Z WILLIAMS A J | 1994 | J Exp Med1994，179，2： | 1 |
| 10 | On the Theory of the formation of martensite显示文摘 | Wechsler M S Lieberman D S Read T A | 1953 | Journal of Metals1953，183，： | 1 |
| 11 | Associations between task, training and social environmental factors and error types involved in rail incidents and accidents 显示文摘 | Read G J Lenne M G Moss S A | 2012 | Acci- dent Analysis & Prevention2012，，： | 1 |
| 12 | T ranscrip tionalregulation of endo thelial cell adhesion molecules:N F2kappaB and cytokine inducible enhancers显示文摘 | Read M A Neish A S | 1995 | FA SEBJ1995，9，10： | 1 |
| 13 | 显示文摘 | Read S M Clarke A E Bacic A et aL Requirements for division of generative nucleus in cultured pollen tubes of Nicotiana | 1993 | Protoplasma1993，174，： | 1 |
| 14 | On the theory of the formation of martensite显示文摘 | Wechsler M S Lieberman D S Read T A | 1953 | Transactions of AIME1953，197，： | 1 |
| 15 | The risk of childhood cancer after neonatal exposure to vitamin K 显示文摘 | KLEBANOFF M A READ J S MILLS J L | 1993 | N Engl J Med1993，329，13： | 1 |
| 16 | Phylogenetic relationships inthe subfamily Bovinae ( Mammalia:Artiodactyla) based on ribosomal DNA显示文摘 | WALL D A DAVIS S K READ B M | 1992 | Journal of Mammal1992，73，： | 1 |
| 17 | Azalea regeneration fromcallus culture显示文摘 | Economous A S Read P E Spanoudaki M J | 1988 | Acta horticuhurae1988，226，1： | 1 |
| 18 | Cubic to orthorhombic diffusionless phase change-experimental and theoretical studies of AuCd 显示文摘 | Lieberman D S Wechsler M S Read T A | 1955 | Journal Appled Physics1955，26，4： | 1 |
| 19 | Using of weakly irregular waveguild theory to calculate eigenfrequeneies, Q value, and RF field functions for gyrotron oscillators显示文摘 | FLIFLET A W READ M E | 1981 | Int J Electronics1981，51，4： | 1 |
| 20 | Light-directed spatially addressable parallel chemical synthesis显示文摘 | Fodor S P A Read J L Pirning M C | 1991 | Science1991，251，15： | 1 |
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