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| 1 | 血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。 | 刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L | 2018 | 中华高血压杂志2018，26，10： | 27 |
| 2 | 高危患者目标血压与心血管病预后显示文摘指南推荐血压目标值应〈140/90 mmHg(1mmHg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。 | B?hm M Schumacher H Teo KK Lonn EM Mahfoud F Mann JF Mancia G Redon J Schmieder RE Sliwa K Weber MA Williams BYusuf S 曲浥晨 叶鹏 | 2017 | 中华高血压杂志2017，25，6： | 14 |
| 3 | Productivity and Undesirable Outputs: A Directional Distance Function Approach显示文摘 | Y.H. Chung R. F?re S. Grosskopf | 1997 | Journal of Environmental Management1997，，3： | 5 |
| 4 | Network DEA显示文摘 | Rolf F?re Shawna Grosskopf | 2000 | Socio-Economic Planning Sciences2000，，1： | 4 |
| 5 | A genetic algorithm for the design of a fuzzy controller for active queue management 显示文摘 | Fatta D G Hoffmann F Re Lo G | 2003 | IEEE Trans on System Man and Cybernetic2003，33，3： | 2 |
| 6 | Productivity changes in Swedish pharamacies 1980–1989: A non-parametric Malmquist approach显示文摘 | R. F?re S. Grosskopf B. Lindgren P. Roos | 1992 | Journal of Productivity Analysis (-)1992，，12： | 2 |
| 7 | 重组脊髓灰质炎病毒用于治疗复发胶质母细胞瘤(英文)显示文摘Background The prognosis of patients with recurrent World Health Organization(WHO)grade IV malignant glioma is dismal,and there is currently no effective therapy.We conducted a dose-finding and toxicity study in this population of patients,evaluating convection-enhanced,intratumoral delivery of the recombinant nonpathogenic polio-rhinovirus chimera(PVSRIPO).PVSRIPO recognizes the poliovirus receptor CD155,which is widely expressed in neoplastic cells of solid tumors and in major components of the tumor microenvironment.Methods We enrolled consecutive adult patients who had recurrent supratentorial WHO grade IV malignant glioma,confirmed on histopathological testing,with measurable disease(contrast-enhancing tumor of≥1 cm and≤5.5 cm in the greatest dimension).The study evaluated seven doses,ranging between 107 and 1010 50%tissue-culture infectious doses(TCID50),first in a dose-escalation phase and then in a dose-expansion phase.Results From May 2012 through May 2017,a total of 61 patients were enrolled and received a dose of PVSRIPO.Dose level-1(5.0×107TCID50)was identified as the phase 2 dose.One dose-limiting toxic effect was observed;a patient in whom dose level 5(1010TCID50)was administered had a grade 4 intracranial hemorrhage immediately after the catheter was removed.To mitigate locoregional inflammation of the infused tumor with prolonged glucocorticoid use,dose level 5 was deescalated to reach the phase 2 dose.In the dose-expansion phase,19%of the patients had a PVSRIPO-related adverse event of grade 3 or higher.Overall survival among the patients who received PVSRIPO reached a plateau of 21%(95%confidence interval,11 to 33)at 24 months that was sustained at 36 months.Conclusions Intratumoral infusion of PVSRIPO in patients with recurrent WHO grade IV malignant glioma confirmed the absence of neurovirulent potential.The survival rate among patients who receivedPVSRIPO immunotherapy was higher at 24 and 36 months than the rate among historical controls. | Desjardins A Gromeier M Herndon JE 2nd Beaubier N Bolognesi DP Friedman AH Friedman HS McSherry F Muscat AM Nair S Peters KB Randazzo D Sampson JH Vlahovic G Harrison WT McLendon RE Ashley D Bigner DD | 2018 | 中华神经外科疾病研究杂志2018，17，4： | 2 |
| 8 | Environmental production functions and environmental directional distance functions显示文摘 | Rolf F?re Shawna Grosskopf Carl A. Pasurka | 2006 | Energy2006，，7： | 2 |
| 9 | Productivity and Undesirable Outputs: A Directional Distance Function Approach显示文摘 | Y.H. Chung R. F?re S. Grosskopf | 1997 | Journal of Environmental Management1997，，3： | 2 |
| 10 | Network DEA显示文摘 | Rolf F?re Shawna Grosskopf | 2000 | Socio-Economic Planning Sciences2000，，1： | 2 |
| 11 | Effects of extracts from Hibiscus macranthus and Basella alba mixture on testosterone production in vitro in adult rat testes slices显示文摘瞄准:为了为生男性征的测量发现一个在试管内系统,芙蓉 macranthus (锦葵科) 和 Basella 白长袍的不同摘录完成一(Basellaceae ) 。方法:从片在二媒介,包含0.5%牛的血清白蛋白( BSA )的任何一个 Krebs-Henseleit 缓冲区或 Dubecco 孵化了的睾丸的睾丸激素的生产是修改的鹰的 medium-F12 火腿滋养的混合( DME/Ham F12 ),在5%的混合物下面,在95%空中的 CO2 也当面被决定或加 Basella 白长袍的余因子和芙蓉 macranthus 的缺席一( HMBA )摘录。结果:睾丸激素生产在在响应余因子(49%) 和水浸膏中等的 DME/Ham F12 孵化的睾丸片被增加(34%-60% 根据冲淡) 。在一样的大气的条件下面,没有到在 Krebs-Henseleit 的刺激缓冲包含 0.5% BSA 的余因子或 HMBA 摘录的睾丸片的积极反应。在与 HMBA 的效果有关的进一步的调查, DME/Ham F12 媒介被使用。从在试管内测试获得的结果证明这项活动在二氯甲烷和甲醇主要是在场的,自从这些摘录由睾丸片在睾丸激素生产导致了增加。结论:睾丸片系统是合适的被用于植物的生男性征的简历有功成分的隔离的进一步的在试管内调查。 | Paul E Moundipa Silvère Ngouela Pierre Kamtchouing Etienne Tsamo Félicité M.Tchouanguep Serge Carreau | 2006 | Asian Journal of Andrology2006，8，1： | 2 |
| 12 | IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells显示文摘 | Strominger JL | 2004 | J Immunol2004，173，12： | 1 |
| 13 | Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4显示文摘 | Bruyère F Hans G | 2004 | BMC Neurosci2004，5，： | 1 |
| 14 | Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin,cholera toxin B subunit and CpG DNA显示文摘 | Holmgren J Adamsson J anjuère F | 2005 | Immunol Lett2005，97，2： | 1 |
| 15 | Efficacy and safety of high-dose cisplatin and cyclophosphamide with glutathione protection in the treatment of bulky advanced epithelial ovarian cancer显示文摘 | Di Re F Bohm S Oriana S | 1990 | Cancer Chemother Pharmacol1990，25，5： | 1 |
| 16 | Zinc and the risk for infectious dis-ease显示文摘 | WalkerC F Black RE | 2004 | Annu Rev Nutr2004，24，： | 1 |
| 17 | Augumented gentamycin otoxicity induced by vancomycin in guinea pigs 显示文摘 | Brummett RE Fox KE Jacobs F | 1990 | Arch Otolaryngol head Neck Surg1990，116，1： | 1 |
| 18 | In vitro regulation of human hemopoiesis by natural killer cells:analysis at a clonal level显示文摘 | Herrmann F Schmidt RE Ritz J | 1987 | Blood1987，69，： | 1 |
| 19 | Topology design,routing and capacity dimensioning for ISL networks in broadband LEO satellite systems显示文摘 | Werner M Reings J Wauquiez F | 2001 | International Journal of Satellite Communication2001，，： | 1 |
| 20 | Selective up-regulation of functional CXCR4 expression in erythroid cells by HIV-1 Tat protein显示文摘 | Gibellini D Re MC Vitone F | 2003 | Clin Exp Immunol2003，131，3： | 1 |
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