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123篇 您的检索式：作者名="Rasko"

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	题名	作者	年代	出处	被引量
1	Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies显示文摘Brain tumors are among the most challenging human tumors for which the mechanisms driving progression and heterogeneity remain poorly understood.We combined single-cell RNA-seq with multi-sector biopsies to sample and analyze single-cell expression profiles of gliomas from 13 Chinese patients.After classifying individual cells;we generated a spatial and temporal landscape of glioma that revealed the patterns of invasion between the different sub-regions of gliomas.We also used single-cell inferred copy number variations and pseudotime trajectories to inform on the crucial branches that dominate tumor progression.The dynamic cell components of the multi-region biopsy analysis allowed us to spatially deconvolute with unprecedented accuracy the transcriptomic features of the core and those of the periphery of glioma at single-cell level.Through this rich and geographically detailed dataset,we were also able to characterize and construct the chemokine and chemokine receptor interactions that exist among different tumor and non-tumor cells.This study provides the first spatial-level analysis of the cellular states that characterize human gliomas.It also presents an initial molecular map of the cross-talks between glioma cells and the surrounding microenvironment with single-cell resolution.	Kai Yu Yuqiong Hu Fan Wu Qiufang Guo Zenghui Qian Waner Hu Jing Chen Kuanyu Wang Xiaoying Fan Xinglong Wu John EJ Rasko Xiaolong Fan Antonio lavarone Tao Jiang Fuchou Tang Xiao-Dong Su	2020	National Science Review2020，7，8：	4
2	The DNA-chip a new tool for medical genetics显示文摘	Falus A Varadi A Rasko I	1998	Orv Hetil1998，139，136：	1
3	Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni,the cyanobacterial symbiont of Lissoclinum patella显示文摘	Schmidt E W Nelson J T Rasko D A		0，，：	1
4	Synthetic Elastin Hydrogels Derived from Massive Elastic Assemblies of Self-organ- ized Human Protein Monomers 显示文摘	Mithieux S M Rasko J E Weiss A S	2004	Biomaterials2004，25，20：	1
5	The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1 显示文摘	Rasko D A Ravel J Okstad O A	2004	Nucleic Acids Res2004，32，3：	1
6	Anti-virulence strategies to combat bacteria- mediated disease 显示文摘	Rasko D A Sperandio V	2010	Nature Reviews Drug Discovery2010，9，2：	1
7	Hydrogen for- mation in ethanol reforming on supported noble metal catalysts 显示文摘	Erdohelyi A Rasko J Kecskes T	2006	Catal Today2006，116，：	1
8	Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens显示文摘	Myers GS Rasko DA Cheung JK	2006	Genome Res2006，16，8：	1
9	Xerodenua pigmentosum varial or Ifig- mented xerodtrmoid 显示文摘	Somos S Sehneider 1 Rasko I	1997	Antieaneer Res1997，17，1：	1
10	Targeting QseC signaling and virulence for antibiotic development显示文摘	RASKO D A MOREIRA C G LI D R	2008	Science2008，321，5892：	1
11	The DNA-chip, a new tool for medical genetics显示文摘	Falus A Varadi A Rasko I	1998	Orv Hetil1998，139，16：	1
12	Genomics of the Bacillus cereus group of organisms显示文摘	Rasko D A Altherr M R Han C S	2005	FEMS Microbiology Reviews2005，29，2：	1
13	DNA microarrays complex human cytomegalovinus genome: profiling kinetic class with drug sensitivity of viral gene expression显示文摘	TROESCH AJ VARADI A RASKO I	1999	Journal of Clinical Microbiology1999，22，2：	1
14	Skewed genomic variability strains of the toxigenic bacterial pathogen, Clostridicum perfringens 显示文摘	MEYERS G S A RASKO D A CHEUNG J K	2006	Genome Res2006，16，7：	1
15	Cell growth inhibition by the multifunctional multivalent zinc-finger factor CTCF显示文摘	RASKO J E KLENOVA E M LEON J	2001	Cancer Res2001，61，16：	1
16	Genomics of the bacillus cereus group of organisms显示文摘	David A Rasko Michael R Altherr Cliff S Han	2005	FEMS Microbiology Reviews2005，29，：	1
17	Concrete creep and shrinkage prediction from short-term tests 显示文摘	Rasko P O Mehdi S Z	1996	ACI Materials Journal1996，93，2：	1
18	Developing strategies for detection of gene doping显示文摘	Baoutina A Alexander I E Rasko J E	2008	J Gene Med2008，10，：	1
19	Aqueous humour-and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling显示文摘	IYENGAR L PATKUNANATHAN B LYNCH OT MCAVOY JW RASKO JE LOVICU FJ	2006	Exp Eye Res2006，83，3：	1
20	Anti-virulence strategies to combatbacteria-mediated disease显示文摘	Rasko D A Sperandio V	2010	Nat Rev Drug Discov2010，，9：	1

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