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	题名	作者	年代	出处	被引量
1	Immune and non-immune responses to hepatitis C virus infection显示文摘The host innate and adaptive immune systems are involved in nearly every step of hepatitis C virus(HCV) infection. In patients,the outcome is determined by a series of complex host-virus interactions,whether it is a natural infection or results from clinical intervention. Strong and persistent CD8+ and CD4+ T-cell responses are critical in HCV clearance,as well as cytokineinduced factors that can directly inhibit virus replication. Newly available direct-acting antivirals(DAAs) are very effective in viral clearance in patients. DAA treatment may further result in the down-regulation of programmed death-1,leading to rapid restoration of HCV-specific CD8+ T cell functions. In this review,we focus on recent studies that address the host responses critical for viral clearance and disease resolution. Additional discussion is devoted to the prophylactic vaccine development as well as to current efforts aimed at understanding the host innate responses against HCV infection. Current theories on how the ubiquitin system and interferon-stimulated genes may affect HCV replication are also discussed.	Jiaren Sun Ricardo Rajsbaum Min Kyung Yi	2015	World Journal of Gastroenterology2015，21，38：	3
2	Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response显示文摘Understanding interactions between the host and SARS-CoV-2 is essential for developing effective vaccines and therapeutics.Here,we report that SARS-CoV-2 usurps the host ubiquitin system to polyubiquitinate accessory protein ORF7a at Lys119.The 0RF7a polyubiquitination is primarily formed by K63-linked ubiquitin chains.	Zengguo Cao Hongjie Xia Ricardo Rajsbaum Xianzhu Xia Hualei Wang Pei-Yong Shi	2021	Cellular & Molecular Immunology2021，18，3：	2
3	Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth ,expression in leaves under short term exposure to osmotic stress or abscisic acid显示文摘	Legaria J Rajsbaum R Munoz Clares R A	1998	Gene1998，218，1：	1
4	TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity显示文摘	Rajsbaum R Garcia Sastre A Versteeg GA	2014	J Mol Biok2014，426，6：	1
5	Tripartite-motif proteins and innate immune regulation显示文摘	McNab FW Rajsbaum R Stoye JP	2011	Curt Opin Immunol2011，23，1：	1
6	Type I interferon-dependent and - independent expression of tripartite motif proteins in immune cells 显示文摘	Rajsbaum R Stoye JP O 'Garra A	2008	EurJImmunol2008，38，3：	1
7	TRIMmunity:the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity显示文摘	Rajsbaum R Garcia-Sastre A Versteeg GA	2014	J Mol Biol2014，426，6：	1
8	Tripartite-motif proteins and innate immune regulation 显示文摘	Mcnab FW Rajsbaum R Stoye JP	2011	Curt Opin Immunol2011，23，1：	1
9	The E3-Ligase TRIM Family of Proteins Regulates Signaling Pathways Triggered by Innate Immune Pattern-Recognition Receptors显示文摘	Gijs A. Versteeg Ricardo Rajsbaum Maria Teresa Sánchez-Aparicio Ana M. Maestre Julio Valdiviezo Mude Shi Kyung-Soo Inn Ana Fernandez-Sesma Jae Jung Adolfo García-Sastre	2013	Immunity2013，，2：	1
10	Type I interferon-depen- dent and -independent expression of tripartite motif proteins in immune cells 显示文摘	Rajsbaum R Stoye JP O'Gan'a A	2008	Eur J Immunol2008，38，3：	1
11	Tripartite motif proteins and innate immune regulation显示文摘	McNab FW Rajsbaum R Stoye JP	2011	Curr Opin Immunol2011，23，1：	1
12	Tripartite-motif proteins and innate immune regulation显示文摘	McNab FW Rajsbaum R Stoye JP	2011	Curr Opin Immunol2011，23，1：	1
13	Tripartite-motif pro- teins and innate immune regulation 显示文摘	McNab FW Rajsbaum R Stoye JP	2011	Curt Opin Immunol2011，23，1：	1
14	Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase - Mediated Antiviral Response显示文摘	Ricardo Rajsbaum Gijs A. Versteeg Sonja Schmid Ana M. Maestre Alan Belicha-Villanueva Carles Martínez-Romero Jenish R. Patel Juliet Morrison Giuseppe Pisanelli Lisa Miorin Maudry Laurent-Rolle Hong M. Moulton David A. Stein Ana Fernandez-Sesma Benjamin R.	2014	Immunity2014，，：	1
15	Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways显示文摘	Ricardo Rajsbaum Adolfo García-Sastre	2013	Trends in Microbiology2013，，：	1
16	Tripartite-motif proteins and innate immune regulation 显示文摘	McNab FW Rajsbaum R Stoye JP	2010	Curr Opin Immunol2010，23，1：	1
17	The E3-ligase TRIM family of proteins regulates signaling path- ways triggered by innate immune pattem-recognition recep- tors显示文摘	Versteeg GA Rajsbaum R Sanchez-Aparicio MT ef al	2013	Immunity2013，38，：	1
18	Tripartite-motif proteins and innate immune regulation显示文摘	McNab F W Rajsbaum R Stoye J P	2010	Curr Opin Immunol2010，23，1：	1
19	Tripartite-motif proteins and innate immune regulation显示文摘	McNab FW Rajsbaum R Stoye JP	2011	Curr Opin Immunol2011，23，1：	1
20	Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth:Expression in leaves under short-term exposure to osmotic stress or abscisic acid显示文摘	Legaria J Rajsbaum R Munoz-Clares R A	1998	Gene1998，218，122：	1

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