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| 1 | Real time endoscopic ultrasound elastography and strain ratio in the diagnosis of solid pancreatic lesions显示文摘AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.RESULTS SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL. | Hussein Okasha Shaimaa Elkholy Ramy El-Sayed Mohamed-Naguib Wifi Mohamed El-Nady Walid El-Nabawi Waleed A El-Dayem Mohamed I Radwan Ali Farag Yahya El-sherif Emad Al-Gemeie Ahmed Salman Mohamed El-Sherbiny Ahmed El-Mazny Reem E Mahdy | 2017 | World Journal of Gastroenterology2017，23，32： | 11 |
| 2 | Enhanced remediation of hydrocarbon contaminated desert soil fertilized with organic carbons显示文摘 | Radwan S S Al-mailem D Ei-Nemr I | 2000 | International Biodeterioration & Biodegradation2000，46，： | 1 |
| 3 | Direct Neurotoxicity of Tetraeaine on Growth Cones and Neurites of Growing Neurons in Vitro显示文摘 | Saito S Radwan I I Obata H et at | 2001 | Anesthesiology2001，95，3： | 1 |
| 4 | The neurotoxitity of local anesthetics on growing neurons:A comparative study of lidocaine,bupivacaine,mepivacaine and ropivacaine显示文摘 | Radwan I Saito S Goto F | 2002 | Anesth Analg2002，94，2： | 1 |
| 5 | Oil biodegradiation around roots显示文摘 | Radwan S Sorkhoh N Ei-nemr I | 1995 | Nature(London)1995，376，： | 1 |
| 6 | Linear active stabiliza-tion of converter-dominated DC microgrids 显示文摘 | RADWAN A A A MOHAMED Y A I | 2012 | IEEE Transactionson Smart Grid2012，，： | 1 |
| 7 | Investigation of static electrification phenomenon due to transformer oil flow in electric power apparatus显示文摘 | Radwan R M E1-Dewieny R M Metwally I A | 1992 | IEEE Transactions on Electrical Insulation1992，27，2： | 1 |
| 8 | Oil biodegradation around roots显示文摘 | Radwan S N Sorkhoh I El-Nemr | 1995 | Nature(London)1995，376，： | 1 |
| 9 | The Neurotoxitity of local anesthetics on growing neurons:A comparative study of lidocaine,bupivacaine,mepivacaine and ropivacaine显示文摘 | Radwan I Saito S Goto F | 2002 | Anesth Analg2002，94，： | 1 |
| 10 | Linear active stabili- zation of converter-dominated DC microgrids显示文摘 | RADWAN A A A MOHAMED Y A R I | 2012 | IEEE Transactions on Smart Grid2012，3，1： | 1 |
| 11 | Metabolism of ambmxol显示文摘 | Puscinska E Radwan I Zielinski J | 1994 | Pneumonol Alergol Pol1994，62，56： | 1 |
| 12 | Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors显示文摘 | Hewedi I H Radwan N A Shash L S | 2012 | Diagn Pathol2012，7，： | 1 |
| 13 | The Neurtoxicitv of Local Anesthetics on Growing Neurons a Comparative Study of Lidocaine, Bupivacaine, Mepivacaine and Ropivacaine 显示文摘 | Radwan I A Saito S Goto F | 2002 | Anesth Analg2002，94，2： | 1 |
| 14 | Detection of intracavitary lesions in 820 infertile women: comparison of outpatient hysteroscopy with histopathological examination显示文摘 | Radwan P Radwan M Polac I | 2013 | Ginekol Pol2013，84，10： | 1 |
| 15 | Botulinum toxin treatment for anal fissure 显示文摘 | Radwan MM Ramdan K Abu- Azab I | 2007 | Afr Health Sci2007，7，1： | 1 |
| 16 | Oil biodegradiation around roots显示文摘 | RADWAN S SORKHOH N EI-NEMR I | 1995 | Nature(London)1995，376，： | 1 |
| 17 | Intraeellular Calcium Increases in Growth Cones Exposed Totetracaine显示文摘 | Saito S Radwan I A Nishikawa K | 2004 | Anesth Analg2004，98，： | 1 |
| 18 | Effect of the concentration of acidic centers in NiNaY zeolite on toluene conversion 显示文摘 | Maskos I Radwan W | 1983 | Kinet Catal Lett1983，22，34： | 1 |
| 19 | Growth Cone Collapsing Effect of Lidoeaine on DRG Neurons Is Partially Reversed by Several Neurotrophic Factors显示文摘 | Radwan I A Saito S Goto F | 2002 | Anesthesiology2002，97，2： | 1 |
| 20 | Neurotrophic Factors Can Partially Reverse Morphological Changes Induced by Mepivacaine and Bupivacaine in Developing Sensory Neurons显示文摘 | Radwan I A Saito S Goto F | 2003 | Anesth Analg2003，97，2： | 1 |
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