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1篇 您的检索式：作者名="Radha Pyati"

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		题名	作者	年代	出处	被引量
	1	Morphological Effects of Natural Products on Schizosaccharomyces pombe Measured by Imaging Flow Cytometry显示文摘Gaining a full understanding of the mechanisms of action of natural products as therapeutic agents includes observing the effects of natural products on cellular morphology,because abnormal cellular morphology is an important aspect of cellular transformations that occur as part of disease states.In this study a set of natural products was examined in search of small molecules that influence the cylindrical morphology of fission yeast Schizosaccharomyces pombe.Imaging flow cytometry of large populations of S.pombe exposed to natural products captured cell images and revealed changes in mean length and aspect ratio of cells.Several natural products were found to alter S.pombe’s morphology relative to control,in terms of elongating cells,shrinking them,or making them more round.These results may facilitate future investigations into methods by which cells establish and maintain specific shapes.	Joel Heisler Lindsay Elvir Farah Barnouti Erica Charles Tom D.Wolkow Radha Pyati	2014	Natural Products and Bioprospecting2014，4，1：	1

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