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	题名	作者	年代	出处	被引量
1	Human cytomegalovirus and Epstein-Barr virus infection in inflammatory bowel disease:Need for mucosal viral load measurement显示文摘AIM:To evaluate the best diagnostic technique and risk factors of the human Cytomegalovirus(HCMV)and Epstein-Barr virus(EBV)infection in inflammatory bowel disease(IBD).METHODS:A cohort of 40 IBD patients(17 refractory)and 40 controls underwent peripheral blood and endoscopic colonic mucosal sample harvest.Viral infection was assessed by quantitative real-time polymerase chain reaction and immunohistochemistry,and correlations with clinical and endoscopic indexes of activity,and risk factors were investigated.RESULTS:All refractory patients carried detectable levels of HCMV and/or EBV mucosal load as comparedto 13/23(56.5%)non-refractory and 13/40(32.5%)controls.The median DNA value was significantly higher in refractory(HCMV 286 and EBV 5.440 copies/105cells)than in non-refractory(HCMV 0 and EBV 6copies/105 cells;P<0.05 and<0.001)IBD patients and controls(HCMV and EBV 0 copies/105 cells;P<0.001 for both).Refractory patients showed DNA peak values≥103 copies/105 cells in diseased mucosa in comparison to non-diseased mucosa(P<0.0121 for HCMV and<0.0004 for EBV),while non-refractory patients and controls invariably displayed levels below this threshold,thus allowing us to differentiate viral colitis from mucosal infection.Moreover,the mucosal load positively correlated with the values found in the peripheral blood,whilst no correlation with the number of positive cells at immunohistochemistry was found.Steroid use was identified as a significant risk factor for both HCMV(P=0.018)and EBV(P=0.002)colitis.Finally,a course of specific antiviral therapy with ganciclovir was successful in all refractory patients with HCMV colitis,whilst refractory patients with EBV colitis did not show any improvement despite steroid tapering and discontinuation of the other medications.CONCLUSION:Viral colitis appeared to contribute to mucosal lesions in refractory IBD,and its correct diagnosis and management require quantitative real-time polymerase chain reaction assay of mucosal specimens.	Rachele Ciccocioppo Francesca Racca Stefania Paolucci Giulia Campanini Lodovica Pozzi Elena Betti Roberta Riboni Alessandro Vanoli Fausto Baldanti Gino Roberto Corazza	2015	World Journal of Gastroenterology2015，21，6：	12
2	Using GIS to identify markets for transit in Delaware显示文摘		1998	The Geographic Information Systems for Transportation Symposium1998，84，：	1
3	Inhedted human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold显示文摘	Chen YS Racca JD Phillips NB	2013	Proc Natl Acad Sci U S A2013，110，38：	1
4	Prospective phase II trial of neo- adjuvant ehemo-radiotherapy with Oxaliplatin and Capecitabine in lo- cally advanced rectal cancer (XELOXART) 显示文摘	Ricardi U Racca P Franco P	2013	Medical oncology2013，30，2：	1
5	Superoxide dismutase and glutathione reductase overexpression in wheat protoplast: photooxidative stress tolerance and changes in cellular redox state显示文摘	Mariana Melchiorre Germán Robert Victorio Trippi Roberto Racca H. Ramiro Lascano	2009	Plant Growth Regulation2009，，1：	1
6	Efficacy and skin toxicity man-agement with cetuximab in metastatic colorectal cancer:outcomes from an oncologic/dermatologic cooperation显示文摘	Pauizia Fanchini	2008	Clin Colorectal Cancer2008，1，7：	1
7	Effects of swim stress and alpha-MSH acute pre-treatment on brain 5-HT trans- porter and corticosterone receptor 显示文摘	Racca S Spaccamiglio A Esculapio P	2005	Pharmacol Biochem Be- hav2005，81，4：	1
8	Differences in Ca2+ p-ermeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression显示文摘	JONAS P RACCA C SAKMANN B	1994	Neuron1994，12，6：	1
9	Moon surface thermal characteristics for moon orbiting spacecraft thermal analysis显示文摘	Racca G D	1995	Planetary Space Science1995，43，：	1
10	Topical use of ra-pamycin in herpetic stromal keratitis显示文摘	ZAPATA G RACCA L TAU J BERRA A	2012	Ocul Immunol In-JZamm2012，20，5：	1
11	SMART-1 technology preparation for future planetary missions显示文摘	MARINI A E RACCA G D FOING B H	2002	Advances in Space Research2002，30，8：	1
12	Prospective phase II trial of neoadjuvant chemo-radiotherapy with Oxaliplatin and Capecitabine in locally advanced rectal cancer (XELOXART)显示文摘	Ricardi U Racca P Franco P	2013	Medical oncology2013，30，2：	1
13	Region-Specific Changes in Gamma and Beta2 Rhythms in NMDA Receptor Dysfunction Models of Schizophrenia 显示文摘	ROOPUM K CUNINGHAM M O RACCA C	2008	Schizophrenic Bull2008，34，5：	1
14	MORO - A European Moon - Orbiting Observatory for Global Lunar Characterization显示文摘	Chincarro A Racca G Coradini M	1994	ESA Journal1994，18，：	1
15	Autocrine Up-Regulation of Glucocorticoid Receptors by Interleukin-6 in Human Osteoblast-Like Cells显示文摘	A. Dovio R.G. Masera M.L. Sartori S. Racca A. Angeli	2001	Calcified Tissue International2001，，5：	1
16	SMART-1 after lunar capture: First results and perspectives显示文摘	B. H. Foing G. D. Racca A. Marini E. Evrard L. Stagnaro M. Almeida D. Koschny D. Frew J. Zender D. Heather M. Grande J. Huovelin H. U. Keller A. Nathues J. L. Josset A. Malkki W. Schmidt G. Noci R. Birkl L. Iess Z. Sodnik P. McManamon	2005	Journal of Earth System Science2005，，6：	1
17	The neuronal splicing factor nova co-localizes with target RNAs in the dendrite显示文摘	RACCA C GARDIOL A EOM T	2010	Front Neural Circuits2010，4，：	1
18	Angiotensin-converting enzyme inhibitors slow recovery from anemia following cardiac surgery显示文摘	Ripamonti V Racca V Calvo MG	2006	Chest2006，130，1：	1
19	Respiratory management of acute respiratory failure in neuromuscular diseases显示文摘	Racca F Del Sorbo L Mongini T	2010	Minerva Anestesiologica2010，76，1：	1
20	How to Select Power-train Isolators for Good Performance and Long Service Life显示文摘	Racca S R	1982	SAE Technical Paper Series1982，，：	1

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