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| 1 | Colorectal cancer and dysplasia in inflammatory bowel disease显示文摘Both ulcerative colitis and Crohn’s disease carry an increased risk of developing colorectal cancer. Established risk factors for cancer among patients with inflammatory bowel disease (IBD) include the younger age at diagnosis, greater extent and duration of disease, increased severity of inflammation, family history of colorectal cancer and coexisting primary sclerosing cholangitis. Recent evidence suggests that current medical therapies and surgical techniques for inflammatory bowel disease may be reducing the incidence of this complication. Nonetheless heightened vigilance and a careful, comprehensive approach to prevent or minimize the complications of invasive cancer are warranted in this unique cohort of patients. Current guidelines for the prevention and early detection of cancer in this high risk population are grounded in the concept of an inflammation-dysplasia- carcinoma sequence. A thorough understanding of the definition and natural history of dysplasia in IBD, as well as the challenges associated with detection and interpretation of dysplasia are fundamental to developing an effective strategy for surveillance and prevention, and understanding the limitations of the current approach to prevention. This article reviews the current consensus guidelines for screening and surveillance of cancer in IBD, as well as presenting the evidence and rationale for chemoprevention of cancer and a discussion of emerging technologies for the detection of dysplasia. | Timothy L Zisman David T Rubin | 2008 | World Journal of Gastroenterology2008，14，17： | 13 |
| 2 | Sox10是一种雪旺细胞和黑色素细胞的广谱标记物显示文摘 | Nonaka D Chiriboga L Rubin B P 樊祥山(摘译) 孟凡青(审校) | 2008 | 临床与实验病理学杂志2008，24，5： | 10 |
| 3 | Choosability in graphs显示文摘 | Erdos P Rubin A L Taylor H | 1979 | Congr Numer1979，26，： | 3 |
| 4 | Effect of Calcineurin Inhibitors in the Outcome of Liver Transplantation in Hepatitis C Virus-Positive Recipients显示文摘 | Marina Berenguer Victoria Aguilera Fernando San Juan Salvador Benlloch Angel Rubin Rafael López-Andujar Angel Moya Eugenia Pareja Eva Montalva Maria Yago Manuel de Juan José Mir Martín Prieto | 2010 | Transplantation2010，，11： | 3 |
| 5 | 糖尿病、糖尿病前期与亚临床心肌损害发生率显示文摘众所周知,处于糖尿病前期者和糖尿病患者存在较高的心血管事件发生风险。然而,糖尿病前期和糖尿病与亚临床心肌损害发生间的关系尚不明确。方法与结果:应用高敏心肌肌钙蛋白T (highly sensitive cardiac troponin T hs-cTnT)分析,测定社区动脉粥样硬化风险研究中9331例受试者两个时间点(间隔6年)的心肌肌钙蛋白T(cardiac troponin T,cTnT)水平,所有受试者为无糖尿病或处于糖尿病前期,或糖尿病不伴心血管疾病(包括心电图检测出来的无临床症状的心肌梗死)。 | Selvin E Lazo M Chen Y Shen L Rubin J McEvoy JW Hoogeveen RC Sharrett AR Ballantyne CM Coresh J 刘莉 | 2014 | 中华高血压杂志2014，22，9： | 2 |
| 6 | Doppler ultrasound color flow imaging in the study of breast cancer: preliminary findings显示文摘 | Adler D D Carson P L Rubin J M | 1990 | Ultrasound MedBiol1990，16，6： | 1 |
| 7 | Potent inhibitors of the hedgehog signaling path- way显示文摘 | BRUNTON S A STIBBARD J H A RUBIN L L | 2008 | J Med Chem2008，51，5： | 1 |
| 8 | Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more eficiently than doesvitamin D2显示文摘 | TRANG H COLE D E RUBIN L A | | American Journal of Clinical Nutrition0，998，68： | 1 |
| 9 | Endothelin-1 sensitivity of porcine coronary arteries is reduced by exercise training and is gender dependent显示文摘 | Jones A W Rubin L J Magliola L | 1999 | JAppl Physiol1999，87，3： | 1 |
| 10 | Meat flavor volatiles: a review of the composition, techniques of analysis, and sensory evaluation显示文摘 | SHAHIDI F RUBIN LJ D'SOUZA L A | 1986 | Critical Reviews in Food Science and Nutrition1986，24，2： | 1 |
| 11 | Cuterebra cutaneous myiasis: case report and world literature review显示文摘 | Delshad E Rubin AI Almeida L | 2008 | Int J Dermatol2008，47，4： | 1 |
| 12 | The effect of ammoniaconcentration on the properties of canola meals produced by the am-monia -methanol/ hexane extraction systems 显示文摘 | DIOSADY L L NACZK M RUBIN L J | 1985 | Food Chem1985，18，2： | 1 |
| 13 | Doppler ultrasound flow imaging in the study of breast cancer:Preliminary findings显示文摘 | Alder D D Carson P L Rubin J M | 1990 | UItrasound Med Biol1990，16，6： | 1 |
| 14 | Kit extracellular and kinase domain mutation in gastrointestinal stromal tumors显示文摘 | Lux M L Rubin B P Biase T L | 2000 | Am J Pathol2000，156，3： | 1 |
| 15 | Doppler ultrasound color flow imaging in the study of breast cancer: preliminary findings显示文摘 | Alder D D Carson P L Rubin J M | 1990 | Ultrasound Med boi11990，16，4： | 1 |
| 16 | The soluble interleukin-2 receptor biology,function and clinical application显示文摘 | RUBIN L A NELSON D L | 1990 | Ann Inter Med1990，113，3： | 1 |
| 17 | An animal model of lower eyelid spacer grafting with acellular dermis 显示文摘 | Fay AM Pieroth L Rubin PA | 2001 | Ophthal Plast Reconstr Surg2001，17，4： | 1 |
| 18 | Soluble interleukin-2 receptors are released from activated human lymphoid cells in vitro显示文摘 | Rubin L A Kurman C C Fritz M E | 1985 | J Immunol1985，135，5： | 1 |
| 19 | Phylogenetic shadowing of primate sequences to find functional regions of the human genome显示文摘 | BOFFELLI D MCAULIFFE J OVCHARENKO I PACHTER L RUBIN E M | 2003 | Science2003，299，： | 1 |
| 20 | Protective role of bradykinin in cardiac anaphylaxis 显示文摘 | RUBIN L E LEVI R | 1995 | Circ Res1995，79，： | 1 |
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