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| 1 | Antibiotics and probiotics in treatment of inflammatory bowel disease显示文摘许多试验性、临床的观察建议肠的微植物群在煽动性的肠疾病(IBD ) 的致病起一个潜在的作用。用抗菌素或职业人员生命学的钠内容的操作代表一种潜在地有效的治疗学的选择。可得到的研究不在 ulcerative (UC ) 支持抗菌素的使用。抗菌素在对待是有效的腐败 Crohn 的疾病(CD ) 的复杂并发症但是他们主要治疗是更争论的使用,尽管这条途径经常并且成功地在临床的实践被采用。有证据关於生命的治疗可以是的那个职业人员在预防和处理有效对中等 UC 温和。相反,成功的学习数据的缺乏目前预防在 CD 的处理的专业版生命学的普遍使用。抗菌素和职业人员生命学看起来在 pouchitis 的处理和预防起一个有益的作用,进一步的审判被保证充分确定他们的临床的功效。 | Paolo Gionchetti Fernando Rizzello Karen M Lammers Claudia Morselli Lucia Sollazzi Samuel Davies Rosy Tambasco Carlo Calabrese Massimo Campieri | 2006 | World Journal of Gastroenterology2006，12，21： | 12 |
| 2 | Primary sclerosing cholangitis as an independent risk factor for colorectal cancer in the context of inflammatory bowel disease: A review of the literature显示文摘To examine and evaluate recent evidence regarding the epidemiology, pathogenesis and management of colorectal cancer(CRC) development in inflammatory bowel disease(IBD)-primary sclerosing cholangitis(PSC) patients. Using the PubMed database, a literature search was conducted for relevant articles in English from the past 10 years. Relevant studies investigating PSC as a risk factor for CRC in IBD in the context of incidence and prevalence, pathogenesis, prevention and prognosis were included in this review. Recent evidence increasingly points to PSC as a significant risk factor in the development of CRC in patients with concomitant IBD. PSC may be an important risk factor for CRC in different populations worldwide. The mechanism for this increase in risk is still unclear. The efficacy of UDCA as a chemopreventive agent remains controversial. Liver transplantation does not halt the development of CRC, although there is not enough evidence to suggest that it is associated with increased incidence of CRC. While routine colonoscopic surveillance should be performed in patients with concurrent PSC and IBD, more high-level evidence is required to support the benefits of the procedure. While many new developments have taken place in the last decade, the pathogenesis and optimal management of CRC development in IBD-PSC patients remain unclear. | Rosy Wang Rupert Leong | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 3 | The complexities underlying age-related macular degeneration: could amyloid beta play an important role?显示文摘Age-related macular degeneration(AMD) causes irreversible loss of central vision for which there is no effective treatment. Incipient pathology is thought to occur in the retina for many years before AMD manifests from midlife onwards to affect a large proportion of the elderly. Although genetic as well as non-genetic/environmental risks are recognized, its complex aetiology makes it difficult to identify susceptibility, or indeed what type of AMD develops or how quickly it progresses in different individuals. Here we summarize the literature describing how the Alzheimer's-linked amyloid beta(Aβ) group of misfolding proteins accumulate in the retina. The discovery of this key driver of Alzheimer's disease in the senescent retina was unexpected and surprising, enabling an altogether different perspective of AMD. We argue that Aβ fundamentally differs from other substances which accumulate in the ageing retina, and discuss our latest findings from a mouse model in which physiological amounts of Aβ were subretinally-injected to recapitulate salient features of early AMD within a short period. Our discoveries as well as those of others suggest the pattern of Aβ accumulation and pathology in donor aged/AMD tissues are closely reproduced in mice, including late-stage AMD phenotypes, which makes them highly attractive to study dynamic aspects of Aβ-mediated retinopathy. Furthermore, we discuss our findings revealing how Aβ behaves at single-cell resolution, and consider the long-term implications for neuroretinal function. We propose Aβ as a key element in switching to a diseased retinal phenotype, which is now being used as a biomarker for latestage AMD. | Savannah A. Lynn Eloise Keeling Rosie Munday Gagandeep Gabha Helen Griffiths Andrew J.Lotery J.Arjuna Ratnayaka | 2017 | Neural Regeneration Research2017，12，4： | 6 |
| 4 | Statistical and environmental analyses for the definition of a regional rainfall threshold system for landslide triggering in Tuscany (Italy)显示文摘这个工作的目的是为在 Tuscany 区域(意大利) 被触发山崩的地区性规模的降雨阀值的决心。与经过山崩的 593 的出现有关的批评降雨事件以持续时间(D) 和紧张(I) 被描绘。我和 D 价值在一张木头木头图被阴谋,一条更低的边界清楚地是显著的:它作为代表联系到 landsliding 的降雨条件的阀值被解释。那被比较也与许多文学阀值证实,但是同时类似的阀值将被有效地为一个地区性的警告系统要过去常的太大的近似影响,是清楚的。因此,进一步的分析被执行根据 seasonality,大小,地点,陆地使用和岩性学区分事件。没有这些,导致的标准在所有事件之中区别不同的组被特定、更有效的阀值描绘。这结果能作为在地区性的规模,最好的结果被最简单的途径获得的示范被解释,在我们的情况中仅仅说明二个降雨参数的一个实验黑盒子模型(我和 D ) 。一套阀值能方便地因此用一条统计途径被定义:相应于四个严厉层次的四阀值借助于预言间隔技术被定义,我们基于降雨记录或天气预报开发了一个原型警告系统。 | ROSI Ascanio SEGONI Samuele CATANI Filippo CASAGLI Nicola | 2012 | Journal of Geographical Sciences2012，22，4： | 5 |
| 5 | Synthesis, characterization, cytotoxicity, DNA cleavage and antimicrobial activity of homodinuclear lanthanide complexes of phenylthioacetic acid显示文摘Lanthanide complexes of Eu(III),Gd(III),Nd(III),Sm(III),and Tb(III)with phenylthioacetic acid were synthesized and characterized by elemental analysis,mass,infrared radiation(IR),electronic spectra,molar conductance,thermogravimetric analysis(TGA),and powder X-ray diffraction(XRD).The results showed that the lanthanide complexes were homodinuclear in nature.The two lanthanide ions were bridged by eight oxygen atoms from four carboxylate groups.Thermal decomposition profiles were consistent with the proposed formulations.Powder XRD studies showed that all the complexes were amorphous in nature.Antimicrobial studies indicated that these complexes exhibited more activity than the ligand itself.The DNA cleavage activity of the ligand and its complexes were assayed on CT DNA using gel electrophoresis in the presence of H2O2.The result showed that the Eu(III)and Nd(III)complexes completely cleaved the DNA.The anticancer activities of the complexes were also studied towards human cervical cancer cell line(HeLa)and colon cancer cells(HCT116)and it was found that the Eu(III)and Nd(III)complexes were more active than the corresponding Gd(III),Sm(III),Tb(III)complexes and the free ligand on both the cancer cells. | T. F. Abbs Fen Reji A. Jeena Pearl Bojaxa A. Rosy | 2013 | Journal of Rare Earths2013，31，10： | 4 |
| 6 | Is bactibilia a predictor of poor outcome of pancreaticoduodenectomy?显示文摘BACKGROUND:Although bile infection has been proposed to increase infective complications following pancreaticoduodenectomy,its association with infective complications and non-infective complications like pancreatic fistula is still controversial.METHODS:Seventy-six patients who had undergone pancreaticoduodenectomy between July 2007 and December 2008 were included in a prospective database and their data analyzed.In all patients intraoperative bile from the bile duct was cultured.Preoperative,intra-operative,and post-operative variables were recorded and analyzed.RESULTS:Bile culture showed positive growth in 35 patients and negative growth in 41.Twenty patients in the positive group underwent ERCP and stenting.The patients with a positive bile culture had a higher incidence of infective complications including intra-abdominal abscess (n=8),wound infection (n=27),bacteremia (n=10),and renal insufficiency (n=9).There was no increase in the rate of non-infective complications of pancreaticoduodenectomy including pancreatic fistula (n=7),delayed gastric emptying (n=9),and post-operative hemorrhage (n=3).The hospital stay was significantly prolonged in the patients with a positive bile culture (P=0.0002).CONCLUSIONS:Pre-operative biliary drainage is significantly associated with bile infection,and bile infection increases the overall rates of infective complications and renal insufficiency.Because of the high incidence of complications is associated with infected bile,routine intra-operative bile culture is recommended in patients undergoing pancreaticoduodenectomy.Pre-operative prophylaxis is dependent on sensitivity of cases to perioperative antibiotics and intraoperative bile culture report.Because of its significant association with infected bile,biliary stenting should be used in strictly selected cases. | Sivanpillay Mahadevan Sivaraj Velayutham Vimalraj Palanichamy Saravanaboopathy Shanmugasundaram Rajendran Sathyanesan Jeswanth Palaniappan Ravichandran Rosy Vennilla Rajagopalan Surendran | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，1： | 2 |
| 7 | U-FAST在先进材料研发中的应用显示文摘本文介绍了升级版的电场辅助烧结技术U-FAST(SPS)技术,该技术采用了现代电源技术,具有更快的加热速度,可以广泛的应用于先进材料的研发。如应用在烧结碳化物(WC-Co)、热电材料(PbTe)、Zr-Cu-Al-Nb(块状金属玻璃)、复合材料、透明陶瓷材料、生物材料、金刚石增加复合材料(EDC)等,并介绍了应用U-FAST工艺生产的特点。在较低温度和较短时间下开始烧结过程且不会产生任何不利的晶粒生长,使U-FAST技术成为生产纳米晶和亚微米材料的理想工艺,将电场辅助烧烧结技术提升到新高度。 | Marcin Rosiński 丁海宁 | 2022 | 粉末冶金工业2022，32，1： | 2 |
| 8 | 肝硬化患者急性肾脏疾病的自然病史显示文摘【据Journal of Hepatology 2020年8月报道】题:肝硬化患者急性肾脏疾病的自然病史(作者Tonon M等)2012年,KDIGO小组提出了急性肾损伤(AKI)、急性肾病(AKD)和慢性肾脏疾病(CKD)的新定义。根据国际腹水俱乐部(ICA)的定义,肝硬化患者中发生的AKI得到了广泛的研究。 | TONON M ROSI S GAMBINO CG 武彤 辛桂杰 | 2020 | 临床肝胆病杂志2020，36，11： | 2 |
| 9 | Synthesis of a chitosan-based chelating resin and its application to the selective concentration and ultratrace detemination of silver in environmental water samples显示文摘 | Rosi Ketrin Katarina Toshio Takayanagi Mitsuko O shima | 2006 | Analytical Chimica Acta2006，，558： | 1 |
| 10 | Frequency domain electrical conductivity measurements of the passive electrical properties of human lymphocytes显示文摘 | Cametti C Rosi A | 1993 | Biochim Biophys Acta1993，1153，1： | 1 |
| 11 | Compound Tellurides and Their Alloys for Peltier Cooling - A Review显示文摘 | Yim W M Rosi F D | 1972 | Solid State Electronics1972，15，： | 1 |
| 12 | Hydrogen storage in microporous metal-organic frameworks 显示文摘 | Rosi N L Eckert J Eddaoudi M | 2003 | Science2003，300，： | 1 |
| 13 | Systematic design of pore size and functionality in isoreticular MOFs and their application in methane storage显示文摘 | Eddaoudi Mohamed Kim Jaheon Rosi Nathaniel Vodak David Wachter Joseph O'Keeffe Michael Yaghi Omar M | 2002 | Science2002，295，： | 1 |
| 14 | Thoracic amyloidomas: Two ease reports of an evasive diagnosis 显示文摘 | Rosie Cresner Shameem Mahmood Jane Chen | 2014 | Jour- nal of the Royal Society of Medicine Open2014，5，6： | 1 |
| 15 | Hydrogen stor- age in microporous metal-organic frameworks 显示文摘 | Rosi N L Eckert J Eddaoudi M | 2003 | Sci- ence2003，300，： | 1 |
| 16 | Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo显示文摘 | Wenwen Chien Dhong Hyun Lee Yun Zheng Peer Wuensche Rosie Alvarez Ding Ling Wen Ahmed M. Aribi Su Ming Thean Ngan B. Doan Jonathan W. Said H. Phillip Koeffler | 2014 | Mol. Carcinog2014，，9： | 1 |
| 17 | Lattice Boltzmann Analysis of Fluid-Structure Interaction with Moving Boundaries显示文摘This work is concerned with the modelling of the interaction of fluid flow with flexibly supported rigid bodies.The fluid flow is modelled by Lattice-Boltzmann Method,coupled to a set of ordinary differential equations describing the dynamics of the solid body in terms its elastic and damping properties.The time discretization of the body dynamics is performed via the Time Discontinuous Galerkin Method.Several numerical examples are presented and highlight the robustness and efficiency of the proposed methodology,by means of comparisons with previously published results.The examples show that the present fluid-structure method is able to capture vortexinduced oscillations of flexibly-supported rigid body. | Alessandro De Rosis Giacomo Falcucci Stefano Ubertini Francesco Ubertini Sauro Succi | 2013 | Communications in Computational Physics2013，13，3： | 1 |
| 18 | A costbenefit Analysis model of product design for recyclability and its application 显示文摘 | Chen Rosy Wei Dundee Navin Chandra Prinz Fritz B | 1994 | IEEE Transactions on Components Packaging and Manufacturing Technology--Part A1994，14，4： | 1 |
| 19 | Memory consolidation of Pavlovian fear conditioning requires nitric oxide signaling in the lateral amygdale 显示文摘 | Schafe GE Bauer EP Rosis S | 2005 | Eur J Neurosci2005，22，1： | 1 |
| 20 | High and selective CO2 uptake ina cobalt adeninate metal-organic framework exhibiting py-rimidine- and amino-decorated pores显示文摘 | An J Geib S J Rosi N L | 2010 | J Am Chem Soc2010，132，： | 1 |
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