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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Bacteriocin-based strategies for food biopreservation显示文摘 | Antonio Gálvez Hikmate Abriouel Rosario Lucas López Nabil Ben Omar | 2007 | International Journal of Food Microbiology2007，，1： | 2 |
| 3 | Optimized Melting at Dalmine with a Digital Electrode Regulation System 显示文摘 | MAURO B F ROSARIO L G | 2001 | MPT International2001，，2： | 1 |
| 4 | Second trimester neutrophil gelatinase associated lipoealin as a potential prediagnostic marker of preeclampsia 显示文摘 | Rosario D Giovanni B Domenico G | 2008 | Acta Obstet Gynecol Scand2008，87，： | 1 |
| 5 | Primary and Reversible Pisa Syndrome in Juvenile Normal Pressure Hydrocephalus 显示文摘 | Leon-Sarmiento FE Pradilla G Del Rosario Zambrano M | 2013 | Aeta Neuropsyehiatr2013，25，1： | 1 |
| 6 | Does the weather influence the occurrence of abomasal displacement in dairy cows?显示文摘 | Cannas J Schauberger G Rosario M | 2004 | Deutsche Tierrztliche Wochenschrift2004，111，： | 1 |
| 7 | Does the weather in- fluence the occurrence of abomasal displacement in dairy cows显示文摘 | Cannas J Schauberger G Rosario M | 2004 | Deutsche Tierarztliehe Wochenschrift2004，111，： | 1 |
| 8 | Analytical stress- strain relationship for concrete confined by steel stirrups and/or FRP jackets显示文摘 | Franco B Rosario G Michelangelo L | 2006 | Journal of Structural Engineering ASCE2006，132，9： | 1 |
| 9 | High pressure and the enzymatic hydrolysis of soybean whey proteins显示文摘 | Penas E Prestamo G Rosario G | 2004 | Food Chem2004，85，4： | 1 |
| 10 | 显示文摘 | Michelle R S Caitlin E M Rosario A G et aI | 2012 | Polymer2012，53，4： | 1 |
| 11 | Miscibility and mechanical properties of poly(ether imide)/poly(ether ether ketone)/liquid crystalline polymer ternary blends显示文摘 | Rosario E S Bretas Donald G B | 1992 | Polymer1992，33，24： | 1 |
| 12 | Tomato root dis- tribution, yield and fruit quality under subsurface drip irrigation 显示文摘 | Machado R M Rosario M D Oliveira G | 2003 | Plant & Soil2003，255，1： | 1 |
| 13 | Oestrogens and the heart 显示文摘 | Rosario GM G Panina | 1999 | Therapie1999，54，3： | 1 |
| 14 | Does the weather influence the occurrence of abomasal dis- placement in dairy cows显示文摘 | Cannas J Schauberger G Rosario M etal | 2004 | Deutsche Tierarztliche Wochensch rift2004，111，： | 1 |
| 15 | Characterization of YAG:Ce powders thermal treated at different temperature显示文摘 | Del Rosario G Ohara S Mancic L | | 0，，： | 1 |
| 16 | Antihypertensive Effects of Peroxisome Proliferator-Activated Receptor-β Activation in Spontaneously Hypertensive Rats显示文摘 | María José Zarzuelo Rosario Jiménez Pilar Galindo Manuel Sánchez Ana Nieto Miguel Romero Ana María Quintela Rocío López-Sepúlveda Manuel Gómez-Guzmán Elvira Bailón Isabel Rodríguez-Gómez Antonio Zarzuelo Julio Gálvez Juan Tamargo Francisco Pérez-Vizcaíno | 2011 | Hypertension2011，，4： | 1 |
| 17 | The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome显示文摘 | Rosario C Zandman-Goddard G Meyron-Hohz EG | 2013 | BMC Med2013，11，： | 1 |
| 18 | Influence of the type, size, and distribution of metal oxide particles on the properties of nanocomposite ultrafiltration membranes显示文摘 | Arsuaga J M Sotto A Rosario G D | 2013 | Journal of Membrane Science2013，428，： | 1 |
| 19 | Robust threshold DSS signatures 显示文摘 | Rosario G Stanislaw J Hugo K | 2001 | Information and Computation2001，164，1： | 1 |
| 20 | Tomato root dis- tribution, yield and fruit quality under different subsurface drip irri- gation regimes and depths显示文摘 | Machado Rui M A Oliveira Maria Do Rosario G | 2005 | Irrigation Science2005，24，1： | 1 |
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