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| 1 | Comparative transcriptomics of Central Asian Vitis vinifera accessions reveals distinct defense strategies against powdery mildew显示文摘Grape powdery mildew(PM),caused by the biotrophic ascomycete Erysiphe necator,is a devastating fungal disease that affects most Vitis vinifera cultivars.We have previously identified a panel of V.vinifera accessions from Central Asia with partial resistance to PM that possess a Ren1-like local haplotype.In this study,we show that in addition to the typical Ren1-associated late post-penetration resistance,these accessions display a range of different levels of disease development suggesting that alternative alleles or additional genes contribute to determining the outcome of the interaction with the pathogen.To identify potential Ren1-dependent transcriptional responses and functions associated with the different levels of resistance,we sequenced and analyzed the transcriptomes of these Central Asian accessions at two time points of PM infection.Transcriptomes were compared to identify constitutive differences and PM-inducible responses that may underlie their disease resistant phenotype.Responses to E.necator in all resistant accessions were characterized by an early up-regulation of 13 genes,most encoding putative defense functions,and a late down-regulation of 32 genes,enriched in transcriptional regulators and protein kinases.Potential Ren1-dependent responses included a hotspot of co-regulated genes on chromosome 18.We also identified 81 genes whose expression levels and dynamics correlated with the phenotypic differences between the most resistant accessions‘Karadzhandahal’,DVIT3351.27,and O34-16 and the other genotypes.This study provides a first exploration of the functions associated with varying levels of partial resistance to PM in V.vinifera accessions that can be exploited as sources of genetic resistance in grape breeding programs. | Katherine C H Amrine Barbara Blanco-Ulate Summaira Riaz Dániel Pap Laura Jones Rosa Figueroa-Balderas M Andrew Walker Dario Cantu | 2015 | Horticulture Research2015，2，1： | 3 |
| 2 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，： | 1 |
| 3 | Green clay and aloe vera peel-off facial masks:response surface methodology applied to the formulation design显示文摘 | Beringhs A O Rosa J M Stulzer H K | 2013 | American Association of Pharmaccu- tical Scientists2013，14，1： | 1 |
| 4 | Diagnosis and epidemiology of cirrhosis 显示文摘 | LEFFON H B ROSA A COHEN M | 2009 | Med Clin N Am2009，93，6： | 1 |
| 5 | Phytoplankton biomass is mainly controlled by hydrology and phosphorus concentrations in tropical hydroelectric reservoirs 显示文摘 | Rangel L M Silva L H S Rosa P | 2012 | Hydrobiologia2012，693，1： | 1 |
| 6 | Comparison of reperfusion regimens with or without tirofiban in ST-elevation acute myocardial infarction显示文摘 | Martínez-Ríos MA Rosas M González H | 2004 | Am J Cardiol2004，93，3： | 1 |
| 7 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 8 | Clinical predictors of obstructive sleep apnea 显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，： | 1 |
| 9 | DirectDetection of Black Carbon in Soils by Py-GC/MS,Carbon-13 NMRSpectroscopy and Thermogravimetric Techniques显示文摘 | DE LA ROSA J M KNICKER H LóPEZ-CAPEL E | 2008 | Soil ScienceSociety of America Journal2008，72，： | 1 |
| 10 | The role of pH on the ultrafiltration for drinking water production in Algarve (Portugal) 显示文摘 | Teixeira M R Lucas H Rosa M J | 2002 | Water Supply2002，2，56： | 1 |
| 11 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 12 | Synthesis and invitro trichomonicidal, giardicidal and amebicidal activity of N-acetamide (sulfona- mide)-2-methyl-4-nitm-IH-imidazoles显示文摘 | EMANUEL H N HUGO T ROSA M P | 2009 | Eur J Med Chem2009，44，7： | 1 |
| 13 | Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways显示文摘 | Schoemaker M H Conde de la Rosa L Buist Homan M | 2004 | Hepatology2004，39，6： | 1 |
| 14 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 15 | Heavy metals and metalloids in sediments from the Llobregat Basin, Spain 显示文摘 | CASAS J M ROSAS H SOLE M | 2003 | Environmental Geology2003，44，3： | 1 |
| 16 | Com-parison of reperfusion regimens with or without tirofiban in ST-elevation acute myocardial infarction显示文摘 | Rosas M Gonzalez H | 2004 | Am J Car-diol2004，93，3： | 1 |
| 17 | Comparison of reperfusion regimens with or without tirofiban in ST-elevation acute myocardial infarction显示文摘 | Martinez-Rios MA Rosas M Gonzalez H | 2004 | Am J Cardiol2004，93，3： | 1 |
| 18 | Clinical predictors of ob- structive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 19 | Optial bioscnsor based on nitrite reductase immobilized in controlled pore glass显示文摘 | ROSA C C CRAZ H J VIDAL M | 2002 | Bioscnsors and Bioelectronics2002，17，12： | 1 |
| 20 | Humor- al and cell-mediated immune responses to different doses of attenuated vaccine against avian infectious bronchitis vi- rus显示文摘 | CINTIA H O ANTNIO C A ROSA A J D M | 2013 | Viral Immunology2013，26，4： | 1 |
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