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| 1 | 国际抗癫痫联盟心理工作组循证建议:成人和儿童癫痫患者的心理治疗显示文摘社会心理因素和癫痫治疗可能对癫痫患者及其家庭的健康相关生活质量(Health-related quality of life,HRQOL)产生显著影响,临床上广泛关注心理评估和治疗在改善HRQOL和癫痫共病中的作用。因此,国际抗癫痫联盟(ILAE)委托心理工作组,基于其最近对癫痫患者心理治疗的Cochrane回顾证据的评估,制定了相关临床建议。近期关于癫痫患者心理治疗随机对照试验的Cochrane回顾是本文的主要证据来源。为提供具有实用意义的指导,我们根据美国神经病学学会证据水平系统以及推荐分级、评估、开发和评价系统对研究设计进行评级。本文是儿童和成人心理学家、神经病学家、精神病学家和神经精神病学家进行国际合作的顶点。ILAE执行委员会审查并批准了这一进程和结论。心理干预的最强证据被确定为最常见的心理健康问题,包括抑郁症、神经认知障碍和药物依从性。针对提高HRQOL和依从性以及减少共病症状(焦虑、抑郁)的心理干预应纳入癫痫综合护理中。一系列的心理策略(如认知行为疗法和正念疗法)为提升癫痫患者生活质量带来希望,也给癫痫临床工作者提供了治疗癫痫共病、应对挑战的临床建议。 | Rosa Michaelis Venus Tang Laura H Goldstein 肖英凤(译) 童馨(审) 慕洁(审) | 2019 | 癫痫杂志2019，5，4： | 9 |
| 2 | Season of the year influences infection rates following total hip arthroplasty显示文摘AIM To research the influence of season of the year on periprosthetic joint infections.METHODS We conducted a retrospective review of the entire Medicare files from 2005 to 2014. Seasons were classified as spring, summer, fall or winter. Regional variations were accounted for by dividing patients into four geographic regions as per the United States Census Bureau(Northeast, Midwest, West and South). Acute postoperative infection and deep periprosthetic infections within 90 d after surgery were tracked. RESULTS In all regions, winter had the highest incidence of periprosthetic infections(mean 0.98%, SD 0.1%) and was significantly higher than other seasons in the Midwest, South and West(P < 0.05 for all) but not the Northeast(P = 0.358). Acute postoperative infection rates were more frequent in the summer and were significantly affected by season of the year in the West.CONCLUSION Season of the year is a risk factor for periprosthetic joint infection following total hip arthroplasty(THA). Understanding the influence of season on outcomes following THA is essential when risk-stratifying patients to optimize outcomes and reduce episode of care costs. | Samuel Rosas Alvin C Ong Leonard T Buller Karim G Sabeh Tsun yee Law Martin W Roche Victor H Hernandez | 2017 | World Journal of Orthopedics2017，8，12： | 4 |
| 3 | Comparative transcriptomics of Central Asian Vitis vinifera accessions reveals distinct defense strategies against powdery mildew显示文摘Grape powdery mildew(PM),caused by the biotrophic ascomycete Erysiphe necator,is a devastating fungal disease that affects most Vitis vinifera cultivars.We have previously identified a panel of V.vinifera accessions from Central Asia with partial resistance to PM that possess a Ren1-like local haplotype.In this study,we show that in addition to the typical Ren1-associated late post-penetration resistance,these accessions display a range of different levels of disease development suggesting that alternative alleles or additional genes contribute to determining the outcome of the interaction with the pathogen.To identify potential Ren1-dependent transcriptional responses and functions associated with the different levels of resistance,we sequenced and analyzed the transcriptomes of these Central Asian accessions at two time points of PM infection.Transcriptomes were compared to identify constitutive differences and PM-inducible responses that may underlie their disease resistant phenotype.Responses to E.necator in all resistant accessions were characterized by an early up-regulation of 13 genes,most encoding putative defense functions,and a late down-regulation of 32 genes,enriched in transcriptional regulators and protein kinases.Potential Ren1-dependent responses included a hotspot of co-regulated genes on chromosome 18.We also identified 81 genes whose expression levels and dynamics correlated with the phenotypic differences between the most resistant accessions‘Karadzhandahal’,DVIT3351.27,and O34-16 and the other genotypes.This study provides a first exploration of the functions associated with varying levels of partial resistance to PM in V.vinifera accessions that can be exploited as sources of genetic resistance in grape breeding programs. | Katherine C H Amrine Barbara Blanco-Ulate Summaira Riaz Dániel Pap Laura Jones Rosa Figueroa-Balderas M Andrew Walker Dario Cantu | 2015 | Horticulture Research2015，2，1： | 3 |
| 4 | The granin family : markers forneuroendocrine cells and tools for the diagnosis of neu-roendocrine tumours 显示文摘 | Rosa P Gerdes H | 1994 | Endocrinol Invest1994，17，： | 1 |
| 5 | Photo- sensitizer in clinical PDT显示文摘 | ALLISON R R DOWNIE G H ROSA C | 2004 | Photodiagnosis and Photo- dynamic Therapy2004，，1： | 1 |
| 6 | Comparative study of the spectroscopic properties of Yb3+/Er3+ codoped tellurite glasses modified with R2O(R = Li,Na and K)显示文摘 | DESIRENA H De la ROSA E ROMERO V H | | 0，，02： | 1 |
| 7 | Circulating microRNAs in patients with coronary artery disease显示文摘 | Fichtlscherer S De Rosa S Fox H | 2010 | Circ Res2010，107，5： | 1 |
| 8 | Auction-based mechanisms for electronic procurement显示文摘 | Chandrashekar T S Narahari Y Rosa C H | 2007 | IEEE Transactions on Automation Science and Engineering2007，4，3： | 1 |
| 9 | Hepatocyte oxidant stress and alcoholic liver disease显示文摘 | CONDE DE LA ROSA L MOSHAGE H NIETO N | 2008 | Rev Esp Enferm Dig2008，100，3： | 1 |
| 10 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，： | 1 |
| 11 | Green clay and aloe vera peel-off facial masks:response surface methodology applied to the formulation design显示文摘 | Beringhs A O Rosa J M Stulzer H K | 2013 | American Association of Pharmaccu- tical Scientists2013，14，1： | 1 |
| 12 | Diagnosis and epidemiology of cirrhosis 显示文摘 | LEFFON H B ROSA A COHEN M | 2009 | Med Clin N Am2009，93，6： | 1 |
| 13 | Phytoplankton biomass is mainly controlled by hydrology and phosphorus concentrations in tropical hydroelectric reservoirs 显示文摘 | Rangel L M Silva L H S Rosa P | 2012 | Hydrobiologia2012，693，1： | 1 |
| 14 | A placebo-controlled trial of exenatide twice-daily added to thiazolidinediones alone or in combination with metformin显示文摘 | Liutkus H Rosas Guzman J Norwood P | 2010 | Diabetes Obes Metab2010，12，12： | 1 |
| 15 | Comparison of reperfusion regimens with or without tirofiban in ST-elevation acute myocardial infarction显示文摘 | Martínez-Ríos MA Rosas M González H | 2004 | Am J Cardiol2004，93，3： | 1 |
| 16 | An integrated analysis of the safety and tolerability of desvenlafaxine compared with placebo in the treatment of major depressive disorder显示文摘 | Clayton A H Kornstein S G Rosas G | 2009 | CNS Spectr2009，14，4： | 1 |
| 17 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 18 | The Effects of Supplementation with Sunflower and Soybean Oils on The Fatty Acid Profile of Milk Fat from Grazing Dairy Cows显示文摘 | REGO O A ROSA H J D PORTUGAL P V | 2005 | Anita Res2005，54，1： | 1 |
| 19 | Clinical predictors of obstructive sleep apnea 显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，： | 1 |
| 20 | A regulatory circuitry comprised of miR- 302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation显示文摘 | Rosa A Brivanlou A H | 2011 | EMBO J2011，30，2： | 1 |
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