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| 1 | Neurocysticercosis:A case report and brief review显示文摘Neurocysticercosis(NCC) is one of the seven neglected endemic zoonoses targeted by the World Health Organization.It is considered a common infection of the nervous system caused by the Tanenia solium and is known to be the primary cause of preventable epilepsy in many developing countries.NCC is commonly resulted by the ingestion of Tanenia solium eggs after consuming undercooked pork,or contaminated water.The parasite can grow in the brain and spinal cord within the nervous system,causing severe headache and seizures beside other pathological manifestations.Immigration and international travel to endemic countries has made this disease common in the United States.NCC can be diagnosed with computed tomography and magnetic resonance imaging of the brain.The treatment of the NCC including cysticidal drugs(eg.,albendazole and praziquantel),and neurosurgical procedure,depending upon a the situation.A patient of Asian origin came to our clinic with complaints of dizziness,headaches and episodes seizures for the past twelve years without proper diagnosis.The computed tomography and magnetic resonance imaging scans indicated multilobulated cystic mass in the brain with the suspicion of neurocysticercosis. | Syed A.A.Rizvi Ayman M.Saleh Hanns Frimpong Hussain M.Al Mohiy Jasmin Ahmed Ronda D.Edwards Sultan S.Ahmed | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，1： | 7 |
| 2 | APOBEC deaminases-mutases with defensive roles for immunity显示文摘In recent years, tremendous progress has been made in the elucidation of the biological roles and molecular mechanisms of the apolioprotein B mRNA-editing enzyme catalytic polypeptide (APOBEC) family of enzymes. The APOBEC family of cytidine deaminases has important functional roles within the adaptive and innate immune system. Activation induced cytidine deaminase (AID) plays a central role in the biochemical steps of somatic hypermutation and class switch recombination during antibody maturation, and the APOBEC 3 enzymes are able to inhibit the mobility of retroelements and the replication of retroviruses and DNA viruses, such as the human immunodeficiency virus type-1 and hepatitis B virus. Recent advances in structural and functional studies of the APOBEC enzymes provide new biochemical insights for how these enzymes carry out their biological roles. In this review, we provide an overview of these recent advances in the APOBEC field with a special emphasis on AID and APOBEC3G. | Courtney PROCHNOW Ronda BRANSTEITTER | 2009 | Science China(Life Sciences)2009，52，10： | 6 |
| 3 | Analysis of the influencing factors of PAEs volatilization from typical plastic products显示文摘The primary emphasis of this research was to investigate the foundations of phthalate(PAEs) pollutant source researches and then firstly confirmed the concept of the coefficient of volatile strength, namely phthalate total content in per unit mass and unit surface area of pollutant sources. Through surveying and evaluating the coefficient of volatile strength of PAEs from typical plastic products, this research carried out reasonable classification of PAEs pollutant sources into three categories and then investigated the relationship amongst the coefficient of volatile strength as well as other environmental factors and the concentration level of total PAEs in indoor air measured in environment chambers.Research obtained phthalate concentration results under different temperature, humidity,the coefficient of volatile strength and the closed time through the chamber experiment. In addition, this study further explored the correlation and ratio of influencing factors that affect the concentration level of total PAEs in environment chambers, including environmental factors, the coefficient of volatile strengths of PAEs and contents of total PAEs in plastic products. The research created an improved database system of phthalate the coefficient of volatile strengths of each type of plastic goods, and tentatively revealed that the volatile patterns of PAEs from different typical plastic goods, finally confirmed that the coefficient of volatile strengths of PAEs is a major factor that affects the indoor air total PAEs concentration, which laid a solid foundation for further establishing the volatile equation of PAEs from plastic products. | Weidong Chen Chenchen Chi Chen Zhou Meng Xia Cees Ronda Xueyou Shen | 2018 | Journal of Environmental Sciences2018，30，4： | 5 |
| 4 | Serelaxin increases the antifibrotic action of rosiglitazone in a model of hepatic fibrosis显示文摘AIM To determine the effect of combined serelaxin and rosiglitazone treatment on established hepatic fibrosis.METHODS Hepatic fibrosis was induced in mice by carbon tetrachloride administration for 6 wk, or vehicle alone(nonfibrotic mice). For the final 2 wk, mice were treated with rosiglitazone, serelaxin, or both rosiglitazone and serelaxin. Serum liver enzymes and relaxin levels were determined by standard methods. The degree of liver collagen content was determined by histology and immunohistochemistry. Expression of type?Ⅰ?collagen was determined by quantitative PCR. Activation of hepatic stellate cells was assessed by alpha-smoothmuscle actin(SMA) levels. Liver peroxisome proliferator activated receptor-gamma coactivator 1 alpha(PGC1α) was determined by Western blotting.RESULTS Treatment of mice with CCl4 resulted in hepatic fibrosis as evidenced by increased liver enzyme levels(ALT and AST), and increased liver collagen and SMA. Monotherapy with either serelaxin or rosiglitazone for 2 wk was generally without effect. In contrast, the combination of serelaxin and rosiglitazone resulted in significantly improved ALT levels(P < 0.05). Total liver collagen content as determined by Sirius red staining revealed that only combination treatment was effective in reducing total liver collagen(P < 0.05). These results were supported by immunohistochemistry for type?Ⅰ?collagen, in which only combination treatment reduced fibrillar collagen levels(P < 0.05). The level of hepatic stellate cell activation was modestly, but significantly, reduced by serelaxin treatment alone, but combination treatment resulted in significantly lower SMA levels. Finally, while hepatic fibrosis reduced liver PGC1α levels, the combination of serelaxin and rosiglitazone resulted in restoration of PGC1α protein levels.CONCLUSION The combination of serelaxin and rosiglitazone treatment for 2 wk was effective in significantly reducing established hepatic fibrosis, providing a potential new treatment strategy. | Robert G Bennett Ronda L Simpson Frederick G Hamel | 2017 | World Journal of Gastroenterology2017，23，22： | 2 |
| 5 | Development of a DOPO-containing benzoxazine and its high-performance flame retardant copolybenzoxazines显示文摘 | M. Spontón G. Lligadas J.C. Ronda M. Galià V. Cádiz | 2009 | Polymer Degradation and Stability2009，，10： | 2 |
| 6 | Max-Mean and Max-Median filters for detection of small-targets 显示文摘 | DESPONDE S D ER M H RONDA V | 1999 | SPIE1999，3809，： | 2 |
| 7 | Pregnancy outcomes in female hairdressers显示文摘 | Ronda E Moen BE García AM | 2010 | Int Arch Occup Environ Health2010，83，8： | 1 |
| 8 | Staling of fresh and frozen gluten-free bread显示文摘 | Ronda F Roos Y.H | | 0，，： | 1 |
| 9 | New developments in the field of luminescent materials for lighting and displays显示文摘 | JUSTEL T NIKOL H RONDA C | 1998 | Angew Chem Int Edit1998，37，22： | 1 |
| 10 | Are you tired : Sleep deprivation compromises nurses' health and jeopardizes patients 显示文摘 | Ronda G Ann E | 2004 | American Journal of Nursing2004，104，3： | 1 |
| 11 | Gelatinization and freeze-concentration effects on recrystallization in corn and potato starch gels显示文摘 | Ronda F Roos Y.H | | 0，，： | 1 |
| 12 | Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool 显示文摘 | Ronda C Pedersen LE Hansen HG | 2014 | Biotechnol Bioeng2014，，8： | 1 |
| 13 | Boron-containing novolac resins as flame retardant materials显示文摘 | MARTIN C RONDA J C CADIZ V | 2006 | Polymer Degradation and Stability2006，91，4： | 1 |
| 14 | 显示文摘 | Kennedy S Ronda S Qin H | 1997 | J Cell Biochem1997，65，： | 1 |
| 15 | Temperature quenching of yellow Ce3+ luminescence in YAG:Ce显示文摘 | Bachmann V Ronda C Meijerink A | | 0，，10： | 1 |
| 16 | 查看详情显示文摘 | Martin C Ronda J.C Cadiz V | | 0，，： | 1 |
| 17 | Recent achievement in research on phosphors for lamps and displays 显示文摘 | Ronda C R | 1997 | Journal of Luminescence1997，7274，： | 1 |
| 18 | Temperature quenching of yellow Ce^2+ luminescence in YAG: Ce显示文摘 | Volker Bachmann Cees Ronda | 2009 | Chemistry of Materials2009，21，： | 1 |
| 19 | Antineutrophil cytoplasmantibodies (ANCA) of IgA isotype in adult Henoch-Sch6nlein purpura显示文摘 | Ronda N Esnault VL Layward L | | 0，，： | 1 |
| 20 | 查看详情显示文摘 | Martin C Ronda J.C Cadiz V | | 0，，： | 1 |
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