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| 1 | Different strategies of treatment for uterine cervical carcinoma stage ⅠB2-ⅡB显示文摘Uterine cervical cancer is the second most common gynecological malignancy. It is estimated that over 35% of tumors are diagnosed at locally advanced disease, stage ⅠB2-ⅡB with an estimated 5-year overall survival of 60%. During the last decades, the initial treatment for these women has been debated and largely varies through different countries. Thus, radical concurrent chemoradiation is the standard of care in United Sated and Canada, and neoadjuvant chemotherapy followed by radical surgery is the first line of treatment in some institutions of Europe, Asia and Latin America. Until today, there is no evidence of which strategy is better over the other. This article describe the evidence as well as the advantages and disadvantages of the main strategies of treatment for women affected by uterine cervical cancer stage ⅠB2-ⅡB. | Lucas Minig María Guadalupe Patrono Nuria Romero Juan Francisco Rodríguez Moreno Jesús Garcia-Donas | 2014 | World Journal of Clinical Oncology2014，5，2： | 46 |
| 2 | 在肝的感染移植接受者显示文摘 Liver transplantation is a standard life-saving procedure for the treatment of many end-stage liver diseases. The success of this procedure may be limited by infectious complications.In this article,we review the contemporary state of infectious complications during the post-operative period,with particular emphasis on those that occur most commonly during the first 6 mo after liver transplantation.Bacteria,and less commonly Candida infections,remain the predominant pathogens during the immediate post-operative period,especially during the first month,and infections caused by drugresistant strains are emerging.Infections caused by cytomegalovirus and Aspergillus sp.present clinically during the'opportunistic'period characterized by intense immunosuppression.As newer potent immunosuppressive therapies with the major aim of reducing allograft rejection are developed,one potential adverse effect is an increase in certain infections.Hence,it is essential for liver transplant centers to have an effective approach to prevention that is based on predicted infection risk,local antimicrobial resistance patterns,and surveillance.A better understanding of the common and most important infectious complications is anticipated to lead to improvements in quality of life and survival of liver transplant recipients. | Fabian A Romero Raymund R Razonable | 2011 | World Journal of Hepatology2011，3，4： | 28 |
| 3 | Epidemiological Evolution of Lung Cancer in the South of Spain from 1990 to 2010显示文摘Background: Changes in lung cancer has been characterized by the increase of cases among women and the increase in adenocarcinomas among other histological subtypes.Methods: Descriptive analysis of cases diagnosed with lung cancer in Hospital Virgen de las Nieves(Spain) from 1990 to 2010,based on five variables(age, sex, smoking, histology and pathological anatomy). The study establishes associations between these variables and compares the results with the literature.Results: 2,026 patients were diagnosed with lung cancer in this period; 1,838 were males(90.7%) and 188 women(9.3%); 1,892 patients(93.4%) were smokers or ex-smokers and 134(6.6%) had never smoked; the most frequent non-small cell histology types were squamous cell carcinoma and adenocarcinoma and it was the most frequent neoplasia in women and were associated with a lower tobacco consumption.Conclusion: The large majority of lung cancer cases is associated with a history of smoking tobacco and there are histopathological differences according to gender and cumulative tobacco smoke load. | Alberto Caballero Vázquez Ana Dolores Romero Ortiz Jose Manuel González de Vega San Román Raimundo García del Moral Bernardino Alcázar Navarrete | 2018 | 中国肺癌杂志2018，21，1： | 17 |
| 4 | Prognostic factors and time-related changes influence results of colorectal liver metastases surgical treatment:A single-center analysis显示文摘AIM:To analyze the prognostic factors involved in survival and cancer recurrence in patients undergoing surgical treatment for colorectal liver metastases(CLM) and to describe the effects of time-related changes on survival and recurrence in these patients.METHODS:From January 1994 to January 2006,236 patients with CLM underwent surgery with the aim of performing curative resection of neoplastic disease at our institution and 189(80%) of these patients underwent resection of CLM with curative intention.Preoperative,intraoperative and postoperative data,including primary tumor and CLM pathology results,were retrospectively reviewed.Patients were divided into two time periods:a first period from January 1994 to January 2000(n = 93),and a second period from February 2000 to January 2006(n = 143).RESULTS:Global survival at 1,3 and 5 years in patients undergoing hepatic resection was 91%,54% and 47%,respectively.Patients with preoperative extrahepatic disease,carcinoembryonic antigen(CEA) levels over 20 ng/dL,more than four nodules or extrahepatic invasion at pathological analysis had worse survival.Tumor recurrence rate at 1 year was 48.3%,being more frequent in patients with preoperative and pathological extrahepatic disease and CEA levels over 20 ng/dL.Although patients in the second time period had more adverse prognostic factors,no differences in overall survival and recurrence were observed between the two periods.CONCLUSION:Despite advances in surgical technique and better adjuvant treatments and preoperative imaging,careful patient staging and selection is crucial to continue offering a chance of cure to patients with CLM. | Josep Martí María Marta Modolo Josep Fuster Jaume Comas Rebeca Cosa Joana Ferrer Victor Molina Juan Romero Constantino Fondevila Ramón Charco Juan Carlos García-Valdecasas | 2009 | World Journal of Gastroenterology2009，15，21： | 9 |
| 5 | Biliary cystadenoma显示文摘The diagnosis of cystadenoma is rare, even more so when located in the extrahepatic bile duct.Unspeciflc clinical signs may lead this pathology to be misdiagnosed.The need for pathological anatomy in order to distinguish cystadenomas from simple biliary cysts is crucial.The most usual treatment nowadays is resection of the bile duct, together with cholecystectomy and Roux-en-Y reconstruction. | Miguel A Hernandez Bartolome Sagrario Fuerte Ruiz Israel Manzanedo Romero Beatriz Ramos Lojo Ignacio Rodriguez Prieto Luis Gimenez Alvira Rosario Granados Carreo Manuel Limones Esteban | 2009 | World Journal of Gastroenterology2009，15，28： | 4 |
| 6 | 医源性男性尿失禁的手术治疗显示文摘前列腺外科手术、冷冻消融术、放射治疗以及尿道重建手术可导致医源性男性尿失禁(IMI),其中前列腺癌根治术是最常见的原因。IMI保守治疗方法有凯格尔训练和盆底肌肉电刺激等,而手术是有效的治疗方式,包括人工括约肌(AUS)植入术、球海绵体悬吊术、经尿道注射填充剂等。这些方法都是通过增加尿道阻力来达到治疗目的。AUS植入术被认为是前列腺切除术后尿失禁治疗的金标准,但它较高的并发症发生率和高昂的费用促使人们寻求更经济、更微创的治疗方法。 | ROMERO Claudio A LIN Hao-cheng WANG Run(撰文) 张林琳 曾津 贺大林(翻译) | 2011 | 现代泌尿外科杂志2011，16，1： | 3 |
| 7 | Framingham研究中年轻成人缺血性脑卒中发病的时间趋势显示文摘中年脑卒中对残疾造成的相关生活质量损失影响极大。在这个年龄段,缺血性脑卒中发病率可能会增加。该研究调查了按照中年和老年发病的脑卒中进行分层的社区样本中,缺血性脑卒中发病率和脑卒中危险因素变化的长期趋势。Framingham研究自1948年开始对脑卒中事件进行监测,研究人员对年龄35.<55和>55岁的患者开始进行随访观察,使用Cox模型检查经年龄和性别调整后的10年缺血性脑卒中发病率。在4个时期内进行线性趋势检验,并控制各期之间的时间距离。 | 刘莉(译) 叶鹏(审校) Aparicio HJ Himali JJ Satizabal CL Pase MP Romero JR Kase CS Beiser A S Seshadri S | 2019 | 中华高血压杂志2019，27，8： | 2 |
| 8 | Natural products:Perspectives in the pharmacological treatment of gastrointestinal anisakiasis显示文摘Objective: To evaluate the activity of different natural products against L3 larvae of Anisakis type I. Methods: Information on investigations into the activity of natural products against the L3 larvae of Anisakis simplex was collected from scientific journals, books, theses and reports via a library and electronic search(using Pubmed, Scopus, Medline, Web of Science and Science Direct). The search terms included: natural products, medicinal plants, essential oils, terpenic derivatives, Anisakis, antinematodal activity. Results: In the literature reviewed numerous papers were found concerning the in vitro and in vivo activity against Anisakis type I of various natural products(plant extracts, essential oils and their major components). Analysis of the results showed that in vitro tests the Melaleuca alternifolia essential oil and the ar-turmerone isolated from Curcuma longa displayed the greatest activity. In vivo, the most active compound was perillaldehyde, the main component of Perilla frutescens essential oil. Conclusions: This study shows that some natural products exhibited promising antianisakis properties. | Valero A Romero MC Gómez-Mateos M Hierro I Navarro MC | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，8： | 2 |
| 9 | Plant protection and growth stimulation by microorganisms: biotechnological applications of Bacilli in agriculture显示文摘 | Alejandro Pérez-García Diego Romero Antonio de Vicente | 2010 | Current Opinion in Biotechnology2010，，2： | 2 |
| 10 | Transmission system expansion planning by an extended genetic algorithm显示文摘 | Gallego R A Monticelli A Romero R | 1998 | IEE Proceedings-Generation Transmission and Distribution1998，145，3： | 2 |
| 11 | A case report of pulmonary coinfection of Strongyloides stercoralis and Pneumocystis jiroveci显示文摘A case of pulmonary coinfection by Strongyloides stercoralis and Pneumocystis jiroveci has been detected in an AIDS patient treated in the Respiratory Intensive Care Unit of the Muniz Hospital.At diagnosis,the patient presented cough with mucopurulent expectoration,dyspnea,fever,bilateral pulmonary infiltrates on the chest X-ray,negative bacilloscopy for acid fast bacteria and a CD4^+ T lymphocytes count of 52 cells/μ L.The microbiological diagnosis was achieved by microscopic observation of the respiratory secretions obtained by bronchoalveolar lavage,while the wet mount examination revealed rhabditiform and filariform larvae of the nematode and foamy exudates,pathognomonic of the pulmonary pneumocystosis.It was the unique case of this association among about 3 000 samples performed in our laboratory in the last 10 years and diagnosed by microscopy.Other complementary stains(a rapid modification of Grocott,Kinyoun and Giemsa) were applied to the smears after the diagnosis of mycotic and parasitary infections achieved by fresh microscopy.Both physicians and microbiologists should take into account the possible coexistence of respiratory pathogens in immunocompromised patients,such as those with AIDS. | Bava AJ Romero MM Prieto R Troncoso A | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 2 |
| 12 | Getting the interactions right: Will higher O3 levels interfere with induced defenses to aphid feeding? 显示文摘 | Menendez A I Romero A M Folcia A M | 2008 | Basic and Applied Ecology2008，10，3： | 1 |
| 13 | How do glucocorticoids influence stress responses? Integrating permissive,suppressive,stimulatory,and preparative actions显示文摘 | SAPOLSKY R M ROMERO L M MUNCK A U | 2000 | Endocr Rev2000，21，1： | 1 |
| 14 | More than 80 R2R3-MYB regulatory genes in the genome of Arabidopsis thaliana显示文摘 | Romero I Fuertes A Benitom J | 1998 | Plant J1998，14，3： | 1 |
| 15 | Tensile Testing of EP-823 and HT-9 After Irradiation in STIP Ⅱ 显示文摘 | Maloy Stuart A Romero T James M R | 2006 | Journal of Nuclear Materials2006，356，123： | 1 |
| 16 | Interception of the electron transport chain in bacteria with hydrophilic redox mediators显示文摘 | Lithgow A M Romero L Sanchez I C | 1986 | J Chem Res Synop1986，，5： | 1 |
| 17 | Test systems and Mathematical Models for Transmission Network Expansion Planning显示文摘 | Romero R Monticelli A Garcia A | 2002 | IEE Proc Gener Transm and Distrib2002，149，1： | 1 |
| 18 | Altera- tions of fibfinolysis in stroke显示文摘 | Hernandez Nunez A Romero Barbero JL Caceres Sansaloni A | 1996 | An Med Intena1996，13，3： | 1 |
| 19 | Type 2 diabetes mellitus and the metabolic syndrome following sleeve gastrectomy in se- verely obese subjects 显示文摘 | Vidal J Ibarzabal A Romero F | 2008 | Obes Surg2008，18，9： | 1 |
| 20 | Nerve growth factor induces the expression of functional FSH receptors in newly formed follicles of the rat ovary 显示文摘 | Romero C Paredes A Dissen G A | 2002 | Endocrinology2002，143，： | 1 |
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