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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | Biochar and denitrification in soils:When,how much and why does biochar reduce N2O emissions 显示文摘 | Cayuela M L Sanchez-Monedero M A Roig A | 2013 | Scientific Reports2013，3，： | 1 |
| 3 | Nitrogen transformation during organic waste composting by the Rutgers system and its effects on pH,EC and maturity of the composting mixtures显示文摘 | SANCHEZ-MONEDERO M A ROIG A PAREDES C | 2001 | Bioresource Technology2001，78，3： | 1 |
| 4 | Relationships between water - soluble carbohydrate and phenol fractions and the humification indices of different organic wastes during composting显示文摘 | Sanchez - Monedero M A Roig A Cegarra J | 1999 | Biores Technol1999，70，： | 1 |
| 5 | Relationships between water-soluble carbohydrate and phenol fractions and the humification indices of different organic wastes during composting显示文摘 | Sanchez-Monedero M A Roig A Cegarra J | 1999 | Bioresource Technology1999，70，2： | 1 |
| 6 | Relationships between water-soluble carbohydrate and phenol fractions and the humification indices of different organic wastes during eomposting 显示文摘 | Sanchez-Monedero M A Roig A Cegarra J | 1999 | Bioresoure Technol1999，70，： | 1 |
| 7 | A new model for static mapping of parallel applications with task and date parallelism显示文摘 | Roig C Ripoll A Senar M Guirado F | 2002 | IEEE Proceedings of the International Parallel and Distributed Processing Symposium2002，7885，： | 1 |
| 8 | Clinical implications of increased plasma angitgensin Ⅱ despite ACE inhibitor therapy in patients with congestive heart failure显示文摘 | Roig E Perez VF Morales M | 2000 | Eur Heart J2000，21，： | 1 |
| 9 | Nitrogen transformation during organic waste composting by the Rutgers system and its effects on pH,EC and maturity of the composting mixtures显示文摘 | Sanchez-Monedero M A Roig A Paredes C | | 0，，： | 1 |
| 10 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Rivera Z S | 1999 | Food Research International1999，32，9： | 1 |
| 11 | Invasive cervical resorption:report on two cases显示文摘 | Roig M MorellóS MercadéM | 2010 | Oral Surg Oral Med Oral Pathol Oral Radiol End2010，110，4： | 1 |
| 12 | Growth of ornamental plants in two composts prepared from agroindustrial wastes显示文摘 | Garcia-gomez A Bemal M P Roig A | 2002 | Bioresource Technology2002，83，1： | 1 |
| 13 | Plagiarism and paraphrasing criteria of college and universi- ty professors显示文摘 | Roig M | 2001 | Ethics & Behavior2001，11，3： | 1 |
| 14 | Influence ofwastewater vs groundwater on young Citrus trees显示文摘 | Reboll V Cerezo M Roig A | 2000 | Journal of the Science of Food and Agriculture2000，80，10： | 1 |
| 15 | Increased expression of the rennin angiotensin system and mast cell density but not of an giotensin convertingenzyme I in late stages of human heart failure 显示文摘 | BADLE M ROIG E PEREZ VILLA F | 2006 | J Heart Lung Transplant2006，25，9： | 1 |
| 16 | Single-nucleotide polymorphisms detected in expressed sequence tags of melon显示文摘 | Morales M Roig E Monforte A J | 2004 | Genome2004，47，2： | 1 |
| 17 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Rivera Z S | 1999 | Food Research International1999，32，9： | 1 |
| 18 | Chromatic dispersion effects in millimeter-wave fiber-optic links based on optically generated electrical modulation formats显示文摘 | FUSTER J M ROIG J C CANDELAS P MARTI J | 2003 | Microwave and Optical Technology Letters2003，36，1： | 1 |
| 19 | Evolution of organic matter and nitrogen during co-composting of olive mill wastewater with solid organic wastes显示文摘 | Paredes C Roig A Bernd M P | 2000 | Biol Fertil Soils2000，32，： | 1 |
| 20 | Growth of ornamental plants in two composts prepared from agroindustrial wastes 显示文摘 | Garcia-Gomez A Bernal M P Roig A | 2002 | Bioresource Technology2002，83，2： | 1 |
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