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| 1 | Chronic HCV infection and inflammation:Clinical impact on hepatic and extra-hepatic manifestations显示文摘The liver has a central role in regulating inflammation by its capacity to secrete a number of proteins that control both local and systemic inflammatory responses. Chronic inflammation or an exaggerated inflammatory response can produce detrimental effects on target organs. Chronic hepatitis C virus(HCV) infection causes liver inflammation by complex and not yet well-understood molecular pathways, including direct viral effects and indirect mechanisms involving cytokine pathways,oxidative stress and steatosis induction. An increasing body of evidence recognizes the inflammatory response in chronic hepatitis C as pathogenically linked to the development of both liver-limited injury(fibrosis, cirrhosis and hepatocellular carcinoma) and extrahepatic HCV-related diseases(lymphoproliferative disease,atherosclerosis, cardiovascular and brain disease). Defining the complex mechanisms of HCV-induced inflammation could be crucial to determine the global impact of infection, to estimate progression of the disease, and to explore novel therapeutic approaches to avert HCVrelated diseases. This review focuses on HCV-related clinical conditions as a result of chronic liver and systemic inflammatory states. | Rosa Zampino Aldo Marrone Luciano Restivo Barbara Guerrera Ausilia Sellitto Luca Rinaldi Ciro Romano Luigi E Adinolfi | 2013 | World Journal of Hepatology2013，5，10： | 13 |
| 2 | Simian virus 40 sequences and expression of the viral large T antigen oneoprotein in human pleomorphie adenomas of parotid glands 显示文摘 | Martinelli M Martini F Rinaldi E | 2002 | Am J Pathol2002，161，4： | 1 |
| 3 | Health-related quality of life and sleep disorders in Parkinson's disease显示文摘 | Scaravilli T Gasparoli E Rinaldi F | 2003 | Neurol Ssi2003，24，： | 1 |
| 4 | Screening-photovoltaic bright solitons in lithium niobate and associated single-mode waveguides显示文摘 | FAZIO E RENZI F RINALDI R | 2004 | Applied Physics Letters2004，85，12： | 1 |
| 5 | Effect of zofenopril and ramipril on cardiovascular mortality in patients with chronic heart failure 显示文摘 | Borghi C Cosentino E R Rinaldi E R | 2013 | Am J Cardiol2013，112，1： | 1 |
| 6 | Comparison of the gravimetric,phenol red, and 14C-PEG-3350 methods to determine water absorption in the rat single-pass intestinal perfusion model显示文摘 | Steven C S Rinaldi M T Vukovinsky K E | 2001 | AAPS Pharm Sci2001，3，3： | 1 |
| 7 | Important source of marine secondary organic aerosol from biogenic amines 显示文摘 | Facchini M C Decesari S Rinaldi M Carbone C Finessi E Mircea M Fuzzi S Moretti F Tagliavini E Ceburnis D O'Dowd C D | 2008 | Environ Sci Technol2008，42，24： | 1 |
| 8 | Health- related quality of life and sleep disorders in Parkinson's disease显示文摘 | Scaravilli T Gasparoli E Rinaldi F | 2003 | Neurol Sci2003，24，： | 1 |
| 9 | Yield response of corn to irrigation and nitrogen fertilization in a Mediterranean environment 显示文摘 | Paolo E D Rinaldi M | 2008 | Field Crops Research2008，105，： | 1 |
| 10 | Appearance of breast masses on sonoelastography with special focus on the diagnosis of fibroadenomas显示文摘 | Fleury E F Rinaldi Quarterly J F Piato S | 2009 | Eur Radiol2009，19，6： | 1 |
| 11 | Outbreak of Entamoeba histolytica and Giardia larnblia infections in travelers returning from the tropics显示文摘 | Delalla F Rinaldi E Santoro D | 1992 | Infection1992，20，2： | 1 |
| 12 | Chronic peritoneal dialysis catheters in children:a fifteen-year experience of the Italian Registry of Pediatric Chronic Peritoneal Dialysis显示文摘 | Rinaldi S Sera F Verrina E | 2004 | Perit Dial Int2004，24，5： | 1 |
| 13 | Cooking of pork Longissimus dorsi at different temperature and relative humidity values:Effects on selected physico-chemical properties 显示文摘 | Chiavaro E Rinaldi M Vittadini E | 2009 | Journal of Food Engineering2009，93，2： | 1 |
| 14 | PPAR c: mediates the anti-in-flammatory effect of simvastatin in an experimental model of zymosan-in-duced multiple organ failure显示文摘 | Rinaldi B Donniacuo M Esposito E | 2011 | Br J Pharmacol2011，163，3： | 1 |
| 15 | Comparison of the gravimetric,phenol red,and 14C-PEG-3350 methods to determine water absorption in rat single-pass intestinal perfusion model显示文摘 | Sutton C S Rinaldi T S Vukovinsky K E | 2001 | AAPS Pharm Sci2001，3，： | 1 |
| 16 | Effects of extrusion on dietary fiber and isoflavone contents of wheat extrudates enriched with wet okara显示文摘 | RINALDI V E A NG P K W BENN1NK M R | 2000 | Cereal Chem2000，77，2： | 1 |
| 17 | The diffused city of the Italian north-east:Identification of urban dynamics using cellular automata urban models 显示文摘 | Bessusi E Gecchini A Rinaldi E | 1998 | Computer Environment and Urban Systems1998，22，5： | 1 |
| 18 | Screening- photovohaic bright solitons in lithium niobate and associated single mode waveguides显示文摘 | FAZIO E RENZI F RINALDI R | 2004 | Applied Physics Letters2004，85，12： | 1 |
| 19 | Health-relatedquality of life and sleep disorders in Parkinson′s disease显示文摘 | Scaravilli T Gasparoli E Rinaldi F | 2003 | Neurol Sci2003，24，： | 1 |
| 20 | The diffused city of the Italian north-east: identification of urban dy- namics using cellular automata urban models 显示文摘 | BESUSSI E CECCHINI A RINALDI E | 1998 | Com- puters Environments and Urban Systems1998，22，5： | 1 |
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