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| 1 | Restoration of common bile duct diameter within 2 weeks after endoscopic stone retraction is a preventive factor for stone recurrence显示文摘Background: Little information is available about the relationship between restoration of common bile duct(CBD) diameter after endoscopic stone retraction and recurrence of CBD stones in elderly patients.The present study was to determine whether restoration of CBD diameter is a preventive factor for CBD stone recurrence in elderly patients who underwent endoscopic retrograde cholangiopancreatography(ERCP).Methods: From January 2006 to December 2010, 238 patients underwent the first and the second session of ERCP for the removal of CBD stones. Among them, 173 were over 65 years old. These patients were divided into recurrent group and non-recurrent group. Restoration of CBD diameter and patients' characteristics were compared.Results: There was no statistical difference in patients' characteristics, associated diseases, or ERCP-related complications between the two groups. Reduction of CBD diameter was significantly larger in the nonrecurrent group(2.7 ± 1.7 mm) compared to that in the recurrent group(1.4 ± 2.3 mm, P = 0.002). The proportion of patients with restoration of CBD diameter were significantly lower in the recurrent group(6/42, 14.3%) compared with that in the non-recurrent group(67/131, 51.1%)(P < 0.01).Conclusions: There is an inverse relationship between restoration of CBD diameter and CBD stone recurrence. Therefore, patients without restoration of CBD diameter within 2 weeks after endoscopic stone removal should be monitored more frequently. | Jin Jeon Sung Uk Lim Chang-Hwan Park Chung-Hwan Jun Seon-Young Park Jong-Sun Rew | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，3： | 25 |
| 2 | Clinical significance and risk factors of postembolization fever in patients with hepatocellular carcinoma显示文摘AIM:To investigate tumor response and survival in patients with postembolization fever(PEF) and to determine the risk factors for PEF.METHODS:Four hundred forty-three hepatocellular carcinoma(HCC) patients who underwent the first session of transcatheter arterial chemoembolization(TACE) between January 2005 and December 2009 were analyzed retrospectively.PEF was defined as a body temperature greater than 38.0 ℃ that developed within 3 d of TACE without evidence of infection.The tumor progression-free interval was defined as the interval from the first TACE to the second TACE based on mRECIST criteria.Clinical staging was based on the American Joint Committee on Cancer tumor,node,metastases(TNM) classification of malignant tumors.All patients were admitted before their 1 st TACE treatment,and blood samples were obtained from all patients before and after treatment.Clinicoradiological variables and host-related variables were compared between two groups:patients with PEF vs patients without PEF.Additionally,variables related to 20-mo mortality and tumor progression-free survival were analyzed.RESULTS:The study population comprised 370(85.4%) men and 73(14.6%) women with a mean age of 62.29 ± 10.35 years.A total of 1836 TACE sessions were conducted in 443 patients,and each patient received between 1 and 27(mean:4.14 ± 3.57) TACE sessions.The mean follow-up duration was 22.23 ± 19.6 mo(range:0-81 mo).PEF developed in 117 patients(26.41%) at the time of the first TACE session.PEF was not associated with 20-mo survival(P = 0.524) or computed tomography(CT) response(P = 0.413) in a univariate analysis.A univariate analysis further indicated that diffuse-type HCC(P = 0.021),large tumor size(≥ 5 cm)(P = 0.046),lipiodol dose(≥ 7 mL,P = 0.001),poor blood glucose control(P = 0.034),alanine aminotransferase(ALT) value after TACE(P = 0.004) and C-reactive protein(CRP) value after TACE(P = 0.036) served as possible risk factors correlated with PEF.The ALT value after TACE(P = 0.021) and lipiodol dose over 7 mL(P = 0.011) were independent risk factors for PEF in the multivariate analysis.For the 20-mo survival,poor blood sugar control(P < 0.001),portal vein thrombosis(P = 0.001),favorable CT response after TACE(P < 0.001),initial aspartate aminotransferase(P = 0.02),initial CRP(P = 0.042),tumor size(P < 0.001),TNM stage(P < 0.001) and lipiodol dose(P < 0.001) were possible risk factors in the univariate analysis.Tumor size(P = 0.03),poor blood sugar control(P = 0.043),and portal vein thrombosis(P = 0.031) were significant predictors of survival in the multivariate analysis.Furthermore,the tumor progression-free interval was closely associated with CRP > 1 mg/dL(P = 0.003),tumor size > 5 cm(P < 0.001),tumor type(poorly defined)(P < 0.001),and lipiodol dose(> 7 mL,P < 0.001).CONCLUSION:PEF has no impact on survival at 20 mo or radiologic response.However,the ALT level after TACE and the lipiodol dose represent significant risk factors for PEF. | Chung Hwan Jun Ho Seok Ki Hoon Ki Lee Kang Jin Park Seon Young Park Sung Bum Cho Chang Hwan Park Young Eun Joo Hyun Soo Kim Sung Kyu Choi Jong Sun Rew | 2013 | World Journal of Gastroenterology2013，19，2： | 7 |
| 3 | Risk factors for hepatocellular carcinoma in patients with drug-resistant chronic hepatitis B显示文摘AIM:To investigate the risk factors and characteristics of hepatocellular carcinoma(HCC) in the patients with drug-resistant chronic hepatitis B(CHB).METHODS:A total of 432 patients with drug-resistant CHB were analyzed retrospectively from January 2004to December 2012. The patients were divided into two groups:the HCC group(n = 57) and the non-HCC group(n = 375). Two groups compared using logistic regression for various patients and viral characteristics in order to identify associated risk factors for HCC.Secondarily,patient and tumor characteristics of HCC patients with na ve CHB(N group,n = 117) were compared to the HCC group(R group,n = 57) to identify any difference in HCC characteristics between them.RESULTS:A significant difference was found for age,platelet count,alpha-fetoprotein(AFP),positivity of HBeAg,seroconversion rate of HBeAg,virologic response,the Child-Pugh score,presence of rtM204I,and the duration of antiviral treatment in non-HCC and HCC group. Cirrhosis,age(> 50 years),HBeAg(+),virologic non-responder status,and rtM204I mutants were independent risk factors for the development of HCC. The R group had lower serum C-reactive protein(CRP) and AFP levels,earlier stage tumors,and a shorter mean tumor surveillance period than the N group. However,the total follow-up duration was not significantly different between the two groups.CONCLUSION:13.2% of patients with drug-resistant CHB developed HCC. Age,cirrhosis,YIDD status,HBeAg status,and virologic response are associated with risk of HCC. Patients with drug-resistant CHB and these clinical factors may benefit from closer HCC surveillance. | Chung Hwan Jun Hyoung Ju Hong Min Woo Chung Seon Young Park Sung Bum Cho Chang Hwan Park Young Eun Joo Hyun Soo Kim Sung Kyu Choi Jong Sun Rew | 2013 | World Journal of Gastroenterology2013，19，40： | 7 |
| 4 | Irritable bowel syndrome: A concise review of current treatment concepts显示文摘Irritable bowel syndrome(IBS) is one of the most common gastrointestinal disorders causing patients to seek medical treatment. It is relatively resource intensive and the source of significant morbidity. Recent insights into the pathophysiology and treatment of IBS has given clinicians more options than ever to contend with this disorder. The purpose of our paper is to review older, 'classic' treatments for IBS as well as newer agents and 'alternative' therapies. We discuss the evidence base of these drugs and provide context to help develop appropriate treatment plans for IBS patients. | Geoffrey C Wall Ginelle A Bryant Michelle M Bottenberg Erik D Maki rew R Miesner | 2014 | World Journal of Gastroenterology2014，20，27： | 5 |
| 5 | Targeted therapy in advanced metastatic colorectal cancer: Current concepts and perspectives显示文摘The introduction of new cytotoxic substances as well as agents that target vascular endothelial growth factor(VEGF)and epidermal growth factor receptor(EGFR)signaling has improved clinical outcome of patients withmetastatic colorectal cancer(mCRC).In this review we summarize the most relevant clinical data on VEGF and EGFR targeting regimens in mCRC.The effects of available treatment strategies for mCRC are often temporary,with resistance and disease progression developing in most patients.Thus,new treatment strategies are urgently needed.Some GI peptides including gastrin and gastrin releasing peptide,certain growth factors such as insulin-like growth factor-ⅠandⅡand neuropeptides such as growth hormone releasing hormone(GHRH)are implicated in the growth of CRC.Experimental investigations in CRC with antagonistic analogs of bombesin/gastrin-releasing peptide,GHRH,and with cytotoxic peptides that can be targeted to peptide receptors on tumors,are summarized in the second part of the review. | Florian Hohla Thomas Winder Richard Greil Ferenc G Rick Norman L Block rew V Schally | 2014 | World Journal of Gastroenterology2014，20，20： | 3 |
| 6 | 发展中国家的可再生能源:沼气的机遇和挑战显示文摘能源对于现代社会至关重要,是社会经济发展最重要的指标之一。尽管科技不断发展,但仍然有约30亿人(主要集中在发展中国家的农村地区),继续通过在传统的炉灶中燃烧生物质资源(如柴薪、秸秆、动物粪便)的方式来满足烹饪的能源需求。这种方式对环境、社会、经济、公众健康都带来极大负面影响。这些地区要实现可持续性发展,开发干净清洁、价格低廉的可再生能源就势在必行。把现有的生物质资源(动物粪便、秸秆、餐厨垃圾、绿色废弃物)提炼成更加清洁高效的能源载体(例如厌氧发酵产生的沼气),不仅具有提供清洁、可靠能源的独特潜力,同时又能保护当地和全球的环境。尽管沼气对发展中国家来说意义重大,但其面临着成本高、设备安装和维护专业知识缺乏等问题,因而在地理位置分散的社区难以广泛推广应用。因此,政府和非政府层面的通力协作就显得至关重要,从而促进沼气技术的更新改造和传播,开发尚未被开发的潜力。文章旨在通过分析沼气技术的现状、挑战和潜力,明确它在发展中国家未来的研究方向和发展传播路径。 | K C Surendra Devin Takara rew G Hashimoto Samir Kumar Khanal 李谦 | 2015 | 中国沼气2015，33，1： | 3 |
| 7 | Sonic testing a simple nondestructive testing for verifying casting quality 显示文摘 | Fuller A G Emerson P J Rew R | 1963 | BCIRA Journal1963，，11： | 1 |
| 8 | Properties of the large ion permeable pores formed from protein F of Pseudomonas aeruginosa in lipid bilayer membranes 显示文摘 | Benz R Hancock REW | 1981 | Biochem Biophys Acta1981，646，： | 1 |
| 9 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies 显示文摘 | Hancock REW Sahl HG 2006 | 2006 | Nat Biotechnol2006，24，12： | 1 |
| 10 | Expression of E cadher- in,alpha- and beta-catenins in patients with pancreatic ad- enocareinoma显示文摘 | Joo YE Rew JS Park CS | 2002 | Pancreatology2002，2，2： | 1 |
| 11 | Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections 显示文摘 | Rew Hancock | 2009 | Emerging Health Threats Journal2009，21，2： | 1 |
| 12 | 焦磷酸铜电镀淋洗废水处理显示文摘 | REWing WGRayford WMDoane | 1989 | 电镀与环保1989，，01： | 1 |
| 13 | 内部审计的研究机会(译文)显示文摘第一章内部审计:历史,演变与展望一、背景现代内部审计职业的产生、成长以及发展是和国际内部审计师协会(IIA)的历史紧密交织在一起的,该协会于1941年成立于美国。在最近出版的《60年的分享中前进》中,记述了IIA的历史,内部审计历史学家Dale L.Flesher写道:国际内部审计师协会的60年历史是辉煌的,尤其是在最近10年的描述中(对IIA50年历史的补充),每一个突出亮点都对其发展作出了贡献。 | 张泽华 rew D.Bailey Audrey A.Gramling | 2014 | 商2014，，18： | 1 |
| 14 | An experimental study of active vibration control of composite structures with a piezo - ceramic actuator and a piezo- film sensor显示文摘 | Rew K H Lee I | 1997 | Smart Materials and Structures1997，6，5： | 1 |
| 15 | An experi-mental study of active vibration control of compositestructures with a piezo-ceramic actuator and a piezo-film sensor 显示文摘 | Hart Jae-Hung Rew Keun-Ho Lee In | 1998 | Smart Materials and Structures1998，6，5： | 1 |
| 16 | Distribution and prevalence of Fusarium crown rot and common root rot pathogens of wheat in Montana显示文摘 | Moya-Elizondo E A Rew L J Jacobsen B J | | Plant Disease0，95，9： | 1 |
| 17 | The relationship between spiritual well-being and psychosocial adjustment in Taiwanese patients with colorectal cancer and a colostomy 显示文摘 | Li CC Rew L Hwang SL | 2012 | Journal of Wound Ostomy & Continence Nursing2012，39，2： | 1 |
| 18 | Protecting youth from early and abusive sexual experiences显示文摘 | Rew L Bowman K | 2008 | Pediatr Nuts2008，34，1： | 1 |
| 19 | Cyclooxygenase-2overexpression correlates with vascular endothelial growth factor expression and tumor angiogenesis in gastric cancer显示文摘 | Joo YE Rew JS Seo YH | 2003 | J Clin Gastroenterol2003，37，1： | 1 |
| 20 | The relationship between spiri-tual well - being and psychosocial adjustment in Taiwanesepatients with colorectal cancer and a colostomy 显示文摘 | Li CC Rew L Hwang SL | 2012 | JournalWound Ostomy Continence Nursing2012，39，2： | 1 |
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