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    题名 作者 年代 出处 被引量
1Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly 2012Cellular & Molecular Immunology2012,9,3:3
2Cubic to orthorhmbic difusionless phase change-experimentaland theoretical studies of aucd显示文摘Lieberman D S Wechsler M S Read T A 1955J Applied Physics1955,26,:2
3The biology of mycorrhiza in the Ericaceae Ⅷ, the role of mycorrhizal infection in heavy metal resistance显示文摘Bradley R Burt A J Read D J 1982New Phytol1982,91,2:2
4Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells显示文摘Read M A Cordle S R Veach R A 1993Proc Natl Acad Sci U S A1993,90,21:2
5Surveillance for the detection of early lung cancer in patients with bronchial dysplasia 显示文摘Jeremy George P Banerjee A K Read C A 2007Thorax2007,62,1:1
6The observation of the non-cova-lent interactions in solution by electrospray ionization massspectrometry: promise, pitfalls and prognosis显示文摘Read S M Currier G Bacic A 1996Carbohydr Res1996,281,:1
7Cyclostratigraphy of late Cambrian carbonate sequences 显示文摘Osleger D A Read J F 1991SEPM1991,67,:1
8Do viscous polysaccharides slow absorption by inhibiting diffusion or convection?显示文摘Edwards C A Johnson I T Read N W 1988European Journal of Clinical Nutrition1988,42,:1
9The nature of the banking relationship: A comparison of the experiences of male and female small business owners 显示文摘McKechnie S A Ennew C T Read L H 1998International Small Business Journal1998,16,3:1
10Structure of a serpin-protease complex shows inhibition by deformation显示文摘HUNTINGTON J A READ R J CARRELL R W 2000Nature2000,407,6806:1
11Invertebrate immunity and the limits of mechanistic immunology 显示文摘LITrLE T J HULTMARK D READ A F 2005Nature Immunology2005,6,7:1
12CD4^+ CD25^+ regulatory T cells inhibit the antigen-dependent expansion of self-reactive T cells in vivo 显示文摘ZwarT D Read S van Driel I R Gleeson P A 2006J Immunol2006,176,:1
13Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis显示文摘READ R W SZALAI A J VOGT S D 2006Exp Eye Res2006,82,3:1
14Scalable and efficient multi-label classification for evolving data streams显示文摘Read J Bifet A Holmes G PfahRINGER B 0,,1:1
15Using the theory of planned behaviour to investigate the determinants of recycling behaviour:a case study from Brixworth,UK显示文摘Tonglet M Phillips P S Read A D 0,,41:1
16The prevalence of Cryptosporidium species and subtypes in human faecal samples in Ireland显示文摘Zintl A Proctor AF Read C 2009Epidemiol Infect2009,137,:1
17Permeability and air retention characteristics of bulk solids materials in relation to modes of dense phase pneumatic conveying 显示文摘MAINWARING N J READ A R 1987Bulk Solids Handling1987,7,3:1
18Correction of the bleeding time with lyophilized platelet infusions in dogs on cardiopulmonary bypass 显示文摘BODE A P LUST R M READ M S 2008Clin Appl Thromb Hemost2008,14,:1
19The 'sweet' side of along pentraxin:how glycosylation affects PTX3 functions in innateimmunity and inflammation 显示文摘Inforzato A Reading PC Barbati E 2012Front Immunol2012,3,:1
20Forces on oscillating foils for propulsion and maneuver- ing显示文摘READ D A HOVER F S TRIANTAFYLLOU M S 2003Journal of Fluids and Structure2003,17,1:1
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