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| 1 | Predicting early outcomes of liver transplantation in young children: The EARLY study显示文摘AIM To determine potentially modifiable predictors of early outcomes after liver transplantation in children of age < 3 years.METHODS This study was a retrospective chart review including all consecutive children of age less than 3-years-old having had a liver transplant done at the Western Canadian referral center from June 2005 to June 2015.Pre-specified potential predictor variables and primary and secondary outcomes were recorded using standard definitions and a case report form. Associations between potential predictor variables and outcomes were determined using univariate and multiple logistic [odds ratio(OR); 95%CI] or linear(effect size, ES; 95%CI) regressions. RESULTS There were 65 children, of mean age 11.9(SD 7.1) mo and weight 8.5(2.1) kg, with biliary-atresia in 40(62%), who had a living related donor [LRD; 29(45%)], split/reduced [21(32%)] or whole liver graft [15(23%)]. Outcomes after liver transplant included: ventilator-days of 12.5(14.1); pediatric intensive care unit mortality of 5(8%); re-operation in 33(51%), hepatic artery thrombosis(HAT) in 12(19%), portal vein thrombosis(PVT) in 11(17%), and any severe complication(HAT, PVT, bile leak, bowel perforation, intraabdominal infection, retransplant, or death) in 32(49%) patients. Predictors of the prespecified primary outcomes on multiple regression were:(1) HAT: split/reduced(OR 0.06; 0.01, 0.76; P = 0.030) or LRD(OR 0.16; 0.03, 0.95; P = 0.044) vs whole liver graft; and(2) ventilator-days: surgeon(P < 0.05), lowest antithrombin(AT) postoperative day 2-5(ES-0.24;-0.47,-0.02; P = 0.034), and split/reduced(ES-12.5;-21.8,-3.2; P = 0.009) vs whole-liver graft. Predictors of the pre-specified secondary outcomes on multiple regression were:(1) any thrombosis: LRD(OR 0.10; 0.01, 0.71; P = 0.021) or split/reduced(OR 0.10; 0.01, 0.85; P = 0.034) vs whole liver graft, and lowest AT postoperative day 2-5(OR 0.93; 0.87, 0.99; P = 0.038); and(2) any severe complication: surgeon(P < 0.05), lowest AT postoperative day 2-5(OR 0.92; 0.86-0.98; P = 0.016), and split/reduced(OR 0.06; 0.01, 0.78; P = 0.032) vs whole-liver graft. CONCLUSION In young children, whole liver graft and surgeon was associated with more complications, and higher AT postoperative day 2-5 was associated with fewer complications early after liver transplantation. | Rashid Alobaidi Natalie Anton Dominic Cave Elham Khodayari Moez Ari R Joffe | 2018 | World Journal of Hepatology2018，10，1： | 2 |
| 2 | Analysis of prestressed concrete pressure vessels显示文摘 | | 1968 | Nuclear Engineering and Design1968，7，： | 1 |
| 3 | Production ofsunflower oil methyl esters by optimized alkali-catalyzedmethanolysis显示文摘 | Rashid U Anwar F Moser B R Ashraf S | 2008 | Biomass and Bioenergy2008，32，12： | 1 |
| 4 | Formal semantic con- flict detection in aspect oriented requirements 显示文摘 | WESTON N CHITCHYAN R RASHID A | 2009 | Requirements Engineering2009，14，4： | 1 |
| 5 | Hall effects on hydromagnetic free convection flow along a porous flat plate with mass transfer显示文摘 | Hossain M A Rashid R I M A | 1987 | J Phys Soc Japan1987，56，1： | 1 |
| 6 | Analysis of prestressed concrete pressure vessels显示文摘 | Rashid Y R | 1968 | Nuclear Engineering and Design1968，7，： | 1 |
| 7 | Plantlet formation from isolated protoplasts of Solanum melongena L显示文摘 | Saxena P K Gill R Rashid A | 1981 | Protoplasma1981，106，： | 1 |
| 8 | Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling 显示文摘 | Inoue M Rashid MH Fujita R | 2004 | Nature Med2004，10，7： | 1 |
| 9 | Optimization of polyol ester production by transesterification of Jatropha-based methyl ester with trimethylolpropane using Taguchi design of experiment显示文摘 | Kamil R N M Yusup S Rashid U | 2011 | Fuel2011，90，6： | 1 |
| 10 | Synthesis of spongy gold nanocrystals with pronounced catalytic activities显示文摘 | Rashid M H Bhattacharjee R R Kotal A | | 0，，17： | 1 |
| 11 | Improve-ment of Aspergillus oryzae for hyperproduction of endoglu-canase: expression cloning of cmc - 1 gene of Aspergillusaculeatus 显示文摘 | Rashid M H Javed M R Kawaguchi T | 2008 | Biotechnol Lett2008，30，12： | 1 |
| 12 | HIV inhibitory cembrane derivatives from a Philippines connection of the soft coral Lobophytum species显示文摘 | Rashid M A Gustafson K R Boyd M R | 2000 | Journal of Nature Products2000，63，： | 1 |
| 13 | Defining and managing overactive bladder: disagreement among the experts显示文摘 | Lee U J Scott V C S Rashid R | 2013 | Urology2013，81，2： | 1 |
| 14 | c-di-GMP (3'-5'- cyclic diguanylic acid ) inhibits Staphylococcus aureus cell-cell interactions and biofilm formation 显示文摘 | Karaolis D K Rashid M H Chythanya R | 2005 | Antimicrob Agents Chemother2005，49，3： | 1 |
| 15 | Skyphoplasty显示文摘 | Rashid R Munk PL Heran M | 2009 | Can Assoc Radiol J2009，60，5： | 1 |
| 16 | Composite surgical sutures with bioactive glass coating显示文摘 | BOCCACCINI A R STAMBOULIS A G RASHID A | 2003 | Journal of Biomedical Materials Research Part B:Applied Biomaterials2003，67，1： | 1 |
| 17 | Supplementary effects of saccharomyces boulardii and bacillus subtilis B10 on digestive enzyme activities,antioxidation capacity and blood homeostasis in Broiler显示文摘 | Rashid R I Li Y L Xu X | 2013 | Int J Agric Biol2013，15，2： | 1 |
| 18 | Effect of thymol and formic acid against ectoparasitic brood miteTropilaelaps clareae in Apis mellifera colonies 显示文摘 | Rashid M Elizabeth SW Shazia R | 2011 | Pakistan Journal of Zoology2011，43，1： | 1 |
| 19 | Synthesis and biological evaluation of ursolie acid-triazolyl deriva- tives as potential anti-cancer agents 显示文摘 | Rashid S Dar B A Majeed R | 2013 | Eur J Med Chem2013，66，： | 1 |
| 20 | Dentists' preferences of anterior tooth proportion-a web-based study显示文摘 | Rosenstiel S F Ward D H Rashid R G | 2000 | J Prosthodont2000，9，3： | 1 |
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