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| 1 | Microscopic colitis:A large retrospective analysis from a health maintenance organization experience显示文摘AIM:To examine the demographic data on a large multi-ethnic population of patients with microscopic colitis (MC) in Southern California and to determine the association of MC with inflammatory bowel disease (IBD) and colorectal cancer.METHODS: All patients diagnosed with MC by colonic biopsy from 1996-2005 were identified utilizing a pathology database. All biopsies were reviewed by experienced pathologists utilizing standard histologic criteria. Patients' medical records were reviewed and data regarding patient age, co-morbidities, sex, ethnicity, and medications were analyzed. An age-and sexmatched standard control group was also generated. Chi-square test was used to evaluate the associations of co-morbidities between lymphocytic colitis (LC), collagenous colitis (CC) and the control group.RESULTS: A total of 547 cases of MC were identif ied,376 patients with LC and 171 patients with CC. The female/male ratio was 3:1 in CC and 2.7:1 in LC patients. Celiac disease (P<0.001), irritable bowel syndrome (IBS) (P<0.001), and thyroid diseases (P<0.001) were found to have a higher occurrence in MC compared to the control group. No statistical differences in the occurrence of colorectal cancer, diabetes and IBD were found between the MC group and the control group.CONCLUSION: This is the largest group of patients with MC known to the authors that has been studied to date. Conditions such as celiac disease, IBS, and thyroid diseases were found to be related to MC. Furthermore, neither an increased risk of colorectal cancer nor IBD was associated with MC in this study. | Kevin T Kao Benito A Pedraza Amy C McClune David A Rios Yi-Qiong Mao Robert H Zuch Michael H Kanter Sony Wirio Chris N Conteas | 2009 | World Journal of Gastroenterology2009，15，25： | 5 |
| 2 | Epidemiology of upper gastrointestinal symptoms in Brazil(Epi Gastro):A population-based study according to sex and age group显示文摘AIM:To determine the prevalences of symptoms consistent with gastroesophageal reflux disease(GERD)and dyspepsia in South America.METHODS:A telephone survey was conducted among adult owners of land-based telephones in S?o Paulo,Brazil,using previously validated computer-assisted sampling and survey protocols.The Portugueselanguage survey included(1)sociodemographic characteristics(e.g.,weight,height,smoking)and comorbidities;(2)dietary habits;(3)presence of symptoms consistent with GERD or dyspepsia within the prior 3mo;and(4)use of medications and other therapies to manage symptoms.Data were stratified post-hoc into three homogeneous geographical regions of S?o Paulo according to the Social Exclusion Indices of the districts and postal codes.Survey response data from each respondent were weighted by the numbers of adults and landline telephones in each household.The analyses were weighted to account for sampling design and to be representative of the S?o Paulo population according to city census data.RESULTS:Among 4570 households contacted,an adult from 3050(66.7%)agreed to participate.The nonresponse rate was 33.3%.The mean(SE)respondent age was 42.6(16.0)years.More than half of all respondents were women(53.1%),aged 18 through 49 years(66.7%),married or cohabitating(52.5%),and/or above normal-weight standards(i.e.,35.3%overweight and 16.3%obese).A total of 26.5%of women were perimenopausal.More than 20%of respondents reported highly frequent symptoms consistent with GERD(e.g.,gastric burning sensation=20.8%)or dyspepsia(e.g.,abdominal swelling/distension=20.9%)at least once per month.Prevalences of these symptoms were significantly(approximately 1.5-to 2.0-fold)higher among women than men but did not vary significantly as a function of advancing age.For instance,14.1%of women reported that they experienced stomach burning(symptom of GERD)at least twice per week,compared to 8.4%of men(P=0.012 byχ2 test).A total of 15.7%of women reported that they experienced abdominal swelling(symptom of dyspepsia)at least twice per week,compared to 6.4%of men(P<0.001byχ2 test).Despite frequent manifestations of GERD or dyspepsia,most(≥90%)respondents reported that they neither received prescription medications fromphysicians,nor took behavioral measures(e.g.,dietary modifications),to manage symptoms.CONCLUSION:Symptoms consistent with dyspepsia and GERD are prevalent in Brazil and represent major public-health and clinical challenges. | Maria do Rosário Dias de Oliveira Latorre Aline Medeiros da Silva Décio Chinzon Jaime N Eisig Telma RP Dias-Bastos | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 3 | Helicobacter pylori Induces Increased Expression of Toll‐Like Receptors and Decreased Toll‐Interacting Protein in Gastric Mucosa that Persists Throughout Gastric Carcinogenesis显示文摘 | Pedro Pimentel‐Nunes Nádia Gon?alves Inês Boal‐Carvalho Luís Afonso Paula Lopes Roberto Roncon‐Albuquerque Rui Henrique Luís Moreira‐Dias Adelino F. Leite‐Moreira Mário Dinis‐Ribeiro | 2012 | Helicobacter2012，，1： | 2 |
| 4 | Energetic-protein supplementation in the last 60 days of gestation improves performance of beef cows grazing tropical pastures显示文摘Background: Nutrition is one of the most important factors that affect animal performance, and it therefore also impacts on financial results in beef systems. In this way, finding the best strategy for feeding supplements is of paramount importance. Aiming to evaluate the effect of supplement feeding strategies for beef cows in the last third of gestation, two experiments were conducted. In Experiment 1, 35 pregnant Nellore cows were assigned to a completely randomized design with four treatments: control, which received no supplement; supplementation for the last 30 d of gestation(30-d; 3.0 kg/d); supplementation for the last 60 d of gestation(60-d; 1.5 kg/d); or supplementation for the last 90 d of gestation(90-d; 1.0 kg/d). All supplemented treatments received the same total amount of supplement throughout the experiment: 90 kg(20% of crude protein). A second experiment(Experiment 2) was delineated to evaluate the effects of the amounts offered in Experiment 1 on intake and metabolism. Four multiparous pregnant Nellore cows were assigned to a 4 × 4 Latin square design, with periods of15 d each.Results: There was a linear effect of the number of days of supplementation on calving body weight(BW; P < 0.05)and a quadratic effect on BW change from parturition to d 31 post-calving(P < 0.05), with cows on the 60-d strategy losing less BW post-calving. No difference was found in offspring birth BW(P > 0.10). A significant linear effect on interval from parturition to conception(P < 0.05) was observed, with the highest calving to conception interval being observed in the 90-d strategy. The level of supplementation did not affect forage intake or neutral detergent fiber digestibility(P > 0.10). Nitrogen excreted through urine tended to increase linearly with the level of supplementation(P < 0.10).Conclusion: Providing 1.5 kg of supplement during the last 60 d of gestation improves cow performance after calving, reducing the magnitude of BW lost, and reduces the number of days from calving to re-conception in the following breeding season compared to the usually recommended period of supplementation of 90 d pre-partum. | Aline Gomes da Silva Mário Fonseca Paulino Edenio Detmann Henrique Jorge Fernandes Lincoln da Silva Amorim Román Enrique Maza Ortega Victor Valério de Carvalho Josilaine Aparecida da Costa Lima Felipe Henrique de Moura Mariana Benevides Monteiro Jéssika Almeida Bitencourt | 2018 | Journal of Animal Science and Biotechnology2018，9，1： | 2 |
| 5 | Floating knee injuries treated with single-incision technique versus traditional antegrade femur fixation:a comparative study显示文摘 | Rios JA Ho-Fung V Ramirez N Hernandez RA | 2004 | Am J Orthop2004，33，9： | 1 |
| 6 | E- valuation of Photodynamic Therapy Using a Light-emitting Diode Lamp against Enterococcus faecalis in Extracted Hu- man Teeth 显示文摘 | Alejandro Rios Jianing He Gerald N Glickman eta/ | 2011 | Journal of Endodontics2011，37，： | 1 |
| 7 | Systemic lack of ca- nonical histamine receptor signaling results in increased resistance to autoimmune encephalomyelitis 显示文摘 | SALIGRAMA N CASE L K DEL RIO R | 2013 | J Immunol2013，191，2： | 1 |
| 8 | Evaluation of human serum albumin cobalt binding assay for the assessment of myocardial ischemia and myocardial infarction显示文摘 | BHAGAVAN N V LAI E M RIOS R A | 2003 | Clin Chem2003，49，： | 1 |
| 9 | RANKL/OPG in primary cultures of osteoblasts from post-menopausal women. Differences between osteoporotic hip fractures and osteoarthritis显示文摘 | Mercè Giner M a José Rios M a José Montoya M a Angeles Vázquez Latifa Naji Ramón Pérez-Cano | 2008 | Journal of Steroid Biochemistry and Molecular Biology2008，，1： | 1 |
| 10 | Evaluation of human se- rum albumin cobalt binding assay for the assessment of myocardial is chemia and myocar- dial infarction显示文摘 | BHAGAVAN N V LAI E M RIOS P A | 2003 | Clin Chen2003，49，4： | 1 |
| 11 | A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress 显示文摘 | Del Rio D Stewart A J Pellegrini N | 2005 | Nutr Metab Cardiovasc Dis2005，15，4： | 1 |
| 12 | Mechanisms of migraine aura revealed by functional MRI in human visual cortex显示文摘 | Hadjikhani N Sanchez Del Rio M Wu O | 2001 | Proc Natl Acad Sci U S A2001，98，8： | 1 |
| 13 | Evaluation of huaman serum albumin cobalt binding assay for the assessment of mayocardial infarction显示文摘 | Bhagavan N V Lai E M Rios P A | 2003 | Clin Chem2003，49，5： | 1 |
| 14 | Evaluation of human serum albumin cobalt binding assay for the assessment of myocardial is chemia and myocardial infarction显示文摘 | Bhagavan N V Lai E M Rios P A | | 0，，04： | 1 |
| 15 | A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress 显示文摘 | Del Rio D Stewart AJ Pellegrini N | 2005 | Nutr Metab Cardiovasc Dis2005，15，4： | 1 |
| 16 | Floraing knee injuries treated with single-incision technique versus traditional antegrade remur fixation : a comparative study显示文摘 | Rios JA Ho-Fung V Ramirez N | 2004 | American Orthopedics2004，，33： | 1 |
| 17 | Methylprednisolone Effect on Brain Volume and Enhancing Lesions in MS Before and During IFN B-1 b显示文摘 | Rio A B Richer N Howard T B K | 2002 | Neurology2002，59，5： | 1 |
| 18 | A review of recent stud- ies on malondialdehyde as toxic molecule and biological marker of oxidative stress 显示文摘 | Rio DD Stewart AJ Pellegrini N | 2005 | Nutr Metab Cardiovas Dis2005，15，： | 1 |
| 19 | ADP-ribosylated proteins asold and new drug targets for anticancer therapy: the example of ARF6显示文摘 | Dani N Barbosa AJ Del Rio A | 2013 | Curr Pharm Des2013，19，4： | 1 |
| 20 | 黄粉虫替代蛋白质饲料对太平洋白虾(凡纳滨对虾)消化性能的影响显示文摘试验旨在评估黄粉虫粉(MM)作为凡纳滨对虾养殖中蛋白质来源的可行性。饲料分为正常饲料和试验饲粮,试验饲料中包含正常饲料85%和MM 15%,两种饲料中均含有氧化铬0.5%作为惰性标记,试验采用表观消化率系数(ADC)对两种饲料进行检测。为评估MM消化价值,对虾饲料中采用鱼粉替代MM,替代比例分别为0%、25%、50%、75%和100%,在清水中饲养6周后,对生长参数和整个虾体成分进行评估。干物质ADC为45.9%,能量ADC为66.5%,粗蛋白质ADC为76.1%,必须氨基酸ADC为72%~86%。MM中蛋氨酸为第一限制性氨基酸。饲料中添加MM后,各组间对虾的体增重、特定生长率、采食量、饲料转化率、存活率和蛋白质合成率均无显著变化(P>0.05),虾体蛋白质含量无显著差异(P>0.05)。而随着鱼粉替代比例上升,虾体脂含量从1.13%升至1.88%。结果表明,黄粉虫粉可作为凡纳滨对虾饲料中的替代蛋白质饲料,但添加时应注意补充蛋氨酸。 | Panini R L Freitas L E L Guimarǎes A M Rios C da Silva M F O Vieira F N Fracalossi D M Samuels R I | 2017 | 饲料博览2017，0，7： | 1 |
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