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| 1 | Laparoscopic sleeve gastrectomy:More than a restrictive bariatric surgery procedure?显示文摘Sleeve gastrectomy(SG) is a restrictive bariatric surgery technique that was first used as part of restrictive horizontal gastrectomy in the original Scopinaro type biliopancreatic diversion. Its good results as a single technique have led to a rise in its use, and it is currently the second most performed technique worldwide. SG achieves clearly better results than other restrictive techniques and is comparable in some aspects to the Roux-en-Y gastric bypass, the current gold standard in bariatric surgery. These benefits have been associated with different pathophysiologic mechanisms unrelated to weight loss such as increased gastric emptying and intestinal transit, and activation of hormonal mechanisms such as increased GLP-1 hormone and decreased ghrelin. The aim of this review was to highlight the salient aspects of SG regarding its historical evolution, pathophysiologic mechanisms, main results, clinical applications and perioperative complications. | David Benaiges Antonio Más-Lorenzo Albert Goday José M Ramon Juan J Chillarón Juan Pedro-Botet Juana A Flores-Le Roux | 2015 | World Journal of Gastroenterology2015,21,41: | 6 |
| 2 | Iron type catalysts for the ozonation of oxalic acid in water显示文摘 | Francisco R J Ramon M E | 2005 | Wat Res2005,39,: | 1 |
| 3 | Trehalose-6-phos- phate synthase as an intrinsic selection marker for plant trans- formation 显示文摘 | Leyman B Avonce N Ramon M | 2006 | Journal of Biotechnology2006,121,: | 1 |
| 4 | Differential effects of pentoxfylline on the hepatic inflammatory response in porcine liver cell cultures increase in inducible nitric oxide synthase expression 显示文摘 | Hoebe K H Gonzalez Ramon N Nijmeijer S M | 2001 | Biochem Pharmacol2001,61,9: | 1 |
| 5 | Catalytic ozonation of oxalic acid in an aqueous TiO2 slurry reactor显示文摘 | Rivas F J Ramon M E | 2002 | Applied Catalysis B:Environmental2002,39,: | 1 |
| 6 | A TiO2/Al2O3 catalyst to improve the ozonation of oxalic acid in water显示文摘 | Rivas F J Ramon M E | 2004 | Applied Catalysis B:Environmental2004,47,: | 1 |
| 7 | Farm tourism, gender and enviroment in Spain 显示文摘 | GARCIA- RAMON M D CANOVES G VALDOVINOS N etal | 1995 | Annalsof Tourism Research1995,,2: | 1 |
| 8 | Timing of hepatitis B vaccination: Its effect on vaccine response in health care workers显示文摘 | Sabido M Gavalda L Olona N Ramon JM | 2007 | Vaccine2007,25,43: | 1 |
| 9 | Optimization of headspace solid-phase micro-extraction for analysis of aromatic com- pounds in vinegar显示文摘 | MEJIAS R C RAMON N M VALME M M | 2002 | 1 Chromatogr A2002,,953: | 1 |
| 10 | Thermal Analysis of Cyclodextrim and Their Inclusion Compounds 显示文摘 | FERDINANDO G CSABA N JOSE RAMON M | 2001 | Thermochimica Aeta2001,380,2: | 1 |
| 11 | Optimization of stir bar sorptive extraetion applied to the determination of volatile eompounds in vinegar显示文摘 | Enrique D G Ramon N M Remedios C M | 2006 | Journal of Chromatography A2006,,1104: | 1 |
| 12 | Headspace solid-phase microextraction analysis of aroma compounds in vinegar Validation study显示文摘 | N M Ramon R C Mejias | 2002 | Journal of Chromatography A2002,,967: | 1 |
| 13 | Specialization of the entomopathogenic nematode Steinerrtema scapterisci with its mutualistic Xenorhabdus symbiont显示文摘 | Sicard M Ramone H Brun N L | 2005 | Naturwissenschaften2005,92,: | 1 |
| 14 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022,19,5: | 0 |
| 15 | Artificial intelligence for characterization of diminutive colorectal polyps:A feasibility study comparing two computer-aided diagnosis systems显示文摘BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal polyps.AIM To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,Japan).CADx influence on the optical diagnosis of an expert endoscopist was also investigated.METHODS AI4CRP was developed in-house and CAD EYE was proprietary software provided by Fujifilm.Both CADxsystems exploit convolutional neural networks.Colorectal polyps were characterized as benign or premalignant and histopathology was used as gold standard.AI4CRP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with values<0.6 indicating benign and values≥0.6 indicating premalignant colorectal polyps.Low confidence characterizations were defined as values 40%around the cut-off value of 0.6(<0.36 and>0.76).Self-critical AI4CRP’s diagnostic performances excluded low confidence characterizations.RESULTS AI4CRP use was feasible and performed on 30 patients with 51 colorectal polyps.Self-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to AI4CRP.CAD EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%specificity.Diagnostic performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed best.CONCLUSION Real-time use of AI4CRP was feasible.Objective confidence values provided by a CADx is novel and self-critical AI4CRP showed higher diagnostic performances compared to AI4CRP. | Quirine Eunice Wennie van der Zander Ramon M Schreuder Ayla Thijssen Carolus H J Kusters Nikoo Dehghani Thom Scheeve Bjorn Winkens Mirjam C M van der Ende-van Loon Peter H N de With Fons van der Sommen Ad A M Masclee Erik J Schoon | 2024 | Artificial Intelligence in Gastrointestinal Endoscopy2024,5,1: | 0 |