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| 1 | Design, synthesis, and biological evaluation of 3, 4-dihydroquinolin-2 (1 H)-one and 1,2,3,4-tetrahydroquinoline-based selective hu- man neuronal nitric oxide synthase (nNOS) inhibitors 显示文摘 | RAMNAUTH J SPEED J MADDAFORD SP | 2011 | J Med Chem2011，54，15： | 1 |
| 2 | First-in- class, dual-action, 3,5-disubstituted indole derivatives having human nitric oxide synthase(nNOS) and norepine- phrine reuptake inhibitory(NERI) activity for the treatmenl of neuropathic pain显示文摘 | MLadenova G Annedi S C Ramnauth J | 2012 | J Med Chem2012，55，7： | 1 |
| 3 | Novel 2- aminobenzothiazoles as selectiw~ neuronal nitric oxide synthase in- hibitors显示文摘 | PATMAN J BHARDWAJ N RAMNAUTH J | 2007 | Bioorg Med Chem Lett2007，17，9： | 1 |
| 4 | Novel, druglike 1,7-disubstituted 2,3,4,5 -tetrahydro-1 H-benzoazepine- based selective inhibitors of hulnan neuronal nitric oxide synthase (nNOS)显示文摘 | ANNEDI SC RAMNAUTH J COSSETTE M | 2012 | Bioorg Med Chem Lett2012，22，7： | 1 |
| 5 | 3,5- Disubstituted indole derivatives as selective human neuronal nitric oxide synthase (nNOS) inhibitors 显示文摘 | ANNEDI SC MADDAFORD SP RAMNAUTH J | 2012 | Bioorg Med Chem Lett2012，22，5： | 1 |
| 6 | Discov- ery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-( 1-( piperi- din~--yl) indolin-5-yl )thiophene-2-carboximidamide as a pre- clinical development candidate for the treatment of migraine显示文摘 | ANNEDI SC MADDAFORD SP RAMNAUTH J | 2012 | Eur J Med Chem2012，55，： | 1 |
| 7 | Discov- ery of cis-N-( 1 -(4-( methylamino ) cyclohexyl ) indolin-6-yl ) thio- phene-2-carboximidamide: a 1,6-disubstituted indoline derivative as a highly selective inhibitor of human neuronal nitric oxide syn- thase (nNOS) without any cardiovascular liabilities 显示文摘 | ANNEDI SC RAMNAUTH J MADDAFORD SP | 2012 | J Med Chem2012，55，2： | 1 |
| 8 | Novel 2-amino-benzothiazoles as selective neuronal nitric oxide synthase inhibitors显示文摘 | Patman J Bhardwaj N Ramnauth J | 2007 | Bioorg Med Chem Lett2007，17，： | 1 |
| 9 | 3, 5-Disubsti-tuted indole derivatives as selective human neuronal nitricoxide synthase (nNOS) inhibitors显示文摘 | Annedi SC Maddaford SP Ramnauth J | 2012 | Bioorg Med Chem Lett2012，22，： | 1 |
| 10 | Discovery of cis-N-(1-(4-(methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: a 1, 6-disubstituted indoline derivative as a highly selective inhibitor of human neuronal nitric oxidesynthase (nNOS) without any cardiovascular liabilities显示文摘 | Annedi SC Ramnauth J Maddaford SP | 2012 | J Med Chem2012，55，： | 1 |
| 11 | Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl) indolin-5-yl) thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine显示文摘 | Annedi SC Maddaford SP Ramnauth J | 2012 | Eur J Med Chem2012，55，： | 1 |
| 12 | Novel, druglike1, 7-disubstituted 2, 3, 4, 5-tetrahydro-1H-benzoazepine-based selective inhibitors of human neuronal nitric oxide synthase (nNOS)显示文摘 | Annedi SC Ramnauth J Cossette M | 2012 | Bioorg Med Chem Lett2012，22，： | 1 |
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