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| 1 | Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling:Influence of smoking显示文摘瞄准:为了调查一个模糊逻辑模型是否能预言肤色,表面的癌症(CRC ) 风险由在世袭 non-polyposis 肤色吸表面的癌症(HNPCC ) 病人产生了。方法:从 Creighton 大学世袭癌症研究所登记的 340 个 HNPCC 失配修理(MMR ) 变化搬运人为当模特儿被选择。年龄依赖者曲线被产生阐明开发 CRC 的概率上的在基因变化(hMLH1 或 hMSH2 ) 之间的联合效果,性,和吸烟地位。结果:在男 hMSH2 变化搬运人的吸烟显著地增加的 CRC 风险(P <
0.05 ) 。hMLH1 变化为男性相对 hMSH2 变化搬运人扩充了 CRC 风险(P <
0.05 ) 。男性们非为 hMLH1 比女性有 CRC 的显著地更高的风险吸烟者(P <
0.05 ) , hMLH1 吸烟者(P <
0.1 ) 并且 hMSH2 吸烟者(P <
0.1 ) 。以在在男性的 hMSH2 的一种剂量依赖者方式的吸烟支持的 CRC (P <
0.05 ) 。有 hMSH2 变化的女性和与 hMLH1 组一起的两性仅仅在广泛的吸烟历史以后表明了吸烟效果(P <
0.05 ) 。结论:由在 HNPCC 病人吸烟的 CRC 提升依赖于基因变化,性和年龄。这些数据证明模糊建模可以启用临床的风险分数的明确的表达,从而允许 CRC 预防策略的 individualization。 | Rhonda M Brand David D Jones Henry T Lynch Randall E Brand Patrice Watson Ramesh Ashwathnayaran Hemant K Roy | 2006 | World Journal of Gastroenterology2006，12，28： | 5 |
| 2 | Effect of Commiphora mukul gum resin on hepatic marker enzymes,lipid peroxidation and antioxidants status in pancreas and heart of streptozotocin induced diabetic rats显示文摘Objective:To study the antioxidant efficacy of Commiphora mukul(C.mukul) gum resin ethanolic extract in streptozotocin(STZ) induced diabetic rats.Methods:The male Wistar albino rats were randomly divided into four groups of eight animals each:Control group(C),CM-treated control group(C_+CMEE),Diabetic control group(D),CM- treated diabetic group(D_+CMEE).Diabetes was induced by intraperitoneal injection of STZ(55 mg/kg/ bwt).After being confirmed the diabetic rats were treated with C.mukul gum resin ethanolic extract(CMEE) for 60 days.The biochemical estimations like antioxidant,oxidative stress marker enzymes and hepatic marker enzymes of tissues were performed.Results:The diabetic rats showed increased level of enzymatic activities aspartate aminotransaminase(AST),alanine aminotransaminase(ALT) in liver and kidney and oxidative markers like lipid peroxidation(LPO) and protein oxidation(PO) in pancreas and heart. Antioxidant enzyme activities were significantly decreased in the pancreas and heart compared to control group.Administration of CMEE(200 mg/kg bw) to diabetic rats for 60 days significantly reversed the above parameters towards normalcy.Conclusions:In conclusion,our data indicate the preventive role of C.mukul against STZ-induced diabetic oxidative stress;hence this plant could be used as an adjuvant therapy for the prevention and/or management of diabetes and aggravated antioxidant status. | Ramesh B Karuna R Sreenivasa Reddy S Haritha K Sai Mangala D Sasi Bhusana Rao B Saralakumari D | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，11： | 3 |
| 3 | Acute ischaemic stroke interventions: large vessel occlusion and beyond显示文摘Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy.Large vessel occlusion(LVO)accounts for up to 38%of acute ischaemic stroke and comes with devastating outcomes for patients,families and society in the pre-intervention era.A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke;this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits.This review article will present a comprehensive overview of LVO management,techniques and devices used,and the future of stroke therapy.In addition,we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion. | Ahmad Sweid Batoul Hammoud Sunidhi Ramesh Daniella Wong Tyler D Alexander Joshua Harrison Weinberg Maureen Deprince Jaime Dougherty Dimitri Jean-Mickael Maamari Stavropoula Tjoumakaris Hekmat Zarzour Michael R Gooch Nabeel Herial Victor Romo David M Hasan Robert H Rosenwasser Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 2 |
| 4 | The High-Strain-Rate Response of Alpha-Titanium:Experiments Deformation Mechanisms and Modeling 显示文摘 | Chichili D R Ramesh K T Hemker K J | 1998 | Acta Mater1998，46，3： | 1 |
| 5 | Kernel-based object tracking显示文摘 | Ramesh V Meer P | 2003 | IEEE Transactions on Pattern Analysis and Machine Intelligence2003，25，5： | 1 |
| 6 | Kernal-based objec tracking显示文摘 | COMANICIU D RAMESH V MEER P | 2003 | IEEE Trans on Pattern Analysis and Machine Inteligence2003，25，： | 1 |
| 7 | Experimental and finite element modeling studies on single-layer and multi-layer 1-3 piezocomposite transducers显示文摘 | RAMESH R PRASAD C D VINOD KUMAR T K | 2006 | Ultrasonics2006，44，2006： | 1 |
| 8 | Kernel-ba-sed object tracking显示文摘 | Comaniciu D Ramesh V P Meer | 2003 | IEEE Trans on Pattern Analysis and Machine Intelligent2003，25，5： | 1 |
| 9 | The high-strain-rate response of alpha-titanium: Experiments, deformation mechanisms and modeling显示文摘 | Chichili D R Ramesh K T Hemker K J | 1998 | Acta Materialia1998，46，3： | 1 |
| 10 | Kernel-based Object Tracking 显示文摘 | Comanieiu D Ramesh V MeerP | 2003 | IEEE Transactions on Pattern Analysis and Machine Intelligence2003，25，5： | 1 |
| 11 | Kernel-based object tracking显示文摘 | Comaniciu D Ramesh V Meer P | 2003 | IEEE Transactions on Pattern Analysis and Machine Intelligence2003，25，5： | 1 |
| 12 | Kernel-based Object Tracking显示文摘 | COMANICIU D RAMESH V MEER P | 2003 | IEEE Transactions on Pattern Analysis Machine Intelligence2003，25，5： | 1 |
| 13 | Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene显示文摘 | SAUNDERS C R RAMESH A SHOCKLEY D C | 2002 | Toxicol Lett2002，129，12： | 1 |
| 14 | Carbothermal reduction and nitridation reaction of SiOx and preoxidized SiOx:formation of α-Si3N4 fibers显示文摘 | RAMESH P D RAO K J | 1994 | J Mater Res1994，9，9： | 1 |
| 15 | Intedeu- kin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells 显示文摘 | ZHENG M BOCANGEL D RAMESH R | 2008 | Mol Cancer Ther2008，7，12： | 1 |
| 16 | Urinary netrin-1 is an early predictive biomarker of acute kidney injury after cardiac surgery显示文摘 | Ramesh G Krawczeski C D Woo J G | | 0，，03： | 1 |
| 17 | Kernel-based object Tracking显示文摘 | COMANICIU D RAMESH V MEER P | | 0，，05： | 1 |
| 18 | Kernel Based Object Tracking 显示文摘 | Comaniciu D Ramesh V Meer P | 2003 | IEEE Transactions on Pattern Analysis and Machine Intelligence2003，25，5： | 1 |
| 19 | Environmental contaminant-mixture effects on CNS development,plasticity,and behavior显示文摘 | Wormley D D Ramesh A Hood D B | 2004 | Toxicol Appl Pharmacol2004，197，1： | 1 |
| 20 | Kernel-based object trac-king显示文摘 | COMANICIU D RAMESH V MEER P | 2003 | IEEE Trans on Pattern Analysis and Machine Intelligence2003，5，5： | 1 |
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