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| 1 | Exosomal microRNAs from mesenchymal stem/stromal cells: Biology and applications in neuroprotection显示文摘Mesenchymal stem/stromal cells(MSCs)are extensively studied as cell-therapy agents for neurological diseases.Recent studies consider exosomes secreted by MSCs as important mediators for MSCs’neuroprotective functions.Exosomes transfer functional molecules including proteins,lipids,metabolites,DNAs,and coding and non-coding RNAs from MSCs to their target cells.Emerging evidence shows that exosomal microRNAs(miRNAs)play a key role in the neuroprotective properties of these exosomes by targeting several genes and regulating various biological processes.Multiple exosomal miRNAs have been identified to have neuroprotective effects by promoting neurogenesis,neurite remodeling and survival,and neuroplasticity.Thus,exosomal miRNAs have significant therapeutic potential for neurological disorders such as stroke,traumatic brain injury,and neuroinflammatory or neurodegenerative diseases and disorders.This review discusses the neuroprotective effects of selected miRNAs(miR-21,miR-17-92,miR-133,miR-138,miR-124,miR-30,miR146a,and miR-29b)and explores their mechanisms of action and applications for the treatment of various neurological disease and disorders.It also provides an overview of state-of-the-art bioengineering approaches for isolating exosomes,optimizing their yield and manipulating the miRNA content of their cargo to improve their therapeutic potential. | Aida Nasirishargh Priyadarsini Kumar Lalithasri Ramasubramanian Kaitlin Clark Dake Hao Sabrina V Lazar Aijun Wang | 2021 | World Journal of Stem Cells2021，13，7： | 2 |
| 2 | Fast k-dimensional tree algo-rithms fornearest neighbor search with application to vector quantization encoding显示文摘 | Ramasubramanian V Paliwal K | 1992 | IEEE Transactions on Signal Proces-sing1992，40，3： | 1 |
| 3 | Colonization ofprobiotic iDacteria and its impact on ornamental fish Puntius conchonius显示文摘 | DIVYA KR ISAMMA A RAMASUBRAMANIAN V | 2012 | J Environ Biol2012，33，3： | 1 |
| 4 | Encoding andrecognition of faces based on the human visual modeland DCT显示文摘 | Ramasubramanian D Venkatesh Y V | 2001 | Pattern Recognition2001，34，12： | 1 |
| 5 | Encoding and recognition of faces based on human visual model and DCT显示文摘 | Ramasubramanian D Venkatesh Y V | 2001 | Pattern Recognition2001，，34： | 1 |
| 6 | Encoding and recog- nition of faces based on the human visual model and DCT显示文摘 | RAMASUBRAMANIAN D VENKATESH Y V | 2001 | Pat- tern Recognition2001，34，12： | 1 |
| 7 | Kinesis: a new approach to replica placement in distributed storage systems 显示文摘 | Maccormick J Murphy N Ramasubramanian V | 2009 | ACM Transactions on Storage ( TOS)2009，4，4： | 1 |
| 8 | An Efficient Approximation-Elimination Algorithm for Nearest-Reighbor Search Based on A Spherical Distance Coordinate Formulation显示文摘 | V Ramasubramanian K K Paliwal | 2002 | Pattern Recognit Lett2002，13，7： | 1 |
| 9 | Encoding and recognition of faces based on the human visual model and DCT显示文摘 | Ramasubramanian D Venkatesh Y V | 2001 | Pattern Recognition2001，34，12： | 1 |
| 10 | Assessment of fluoride contamination in groundwater using GIS, Dharmapuri District, Tamilnadu, India显示文摘 | SENDESH K K RAMASUBRAMANIAN V | 2011 | International Journal of Engi- neering Science and Technology2011，3，2： | 1 |
| 11 | Encoding and recognition of faces based on the human visual model and DCT显示文摘 | Ramasubramanian D Venkatesh Y V | 2001 | Pattem Recognition2001，34，12： | 1 |
| 12 | Effect of host plants on some biological aspects of spotted pod-borer Maruca testulalis (Lepidoptera- Pyralidae) 显示文摘 | RAMASUBRAMANIAN G V SUNDARABABU P C | 1988 | Indian Journal Agriculture Science1988，58，8： | 1 |
| 13 | Encoding and recognition of faces based on human visual model and DCT显示文摘 | Ramasubramanian D Venkatesh Y V | 2001 | Pattern Recognition2001，，34： | 1 |
| 14 | An efficient approximation -elimination algorithm for fast nearest-neighbor, search based on a spherical distance coordinate formulation 显示文摘 | Ramasubramanian V and Paliwal Kuldip K | 1992 | Pattem Recognition Letters1992，7，13： | 1 |
| 15 | Analysis of temperature in brake disc for fade assessment显示文摘 | H Ramasubramanian K N Seeth-aramu | 1989 | Warme-und Stoffubertragung1989，24，： | 1 |
| 16 | Fast K-dimensional tree algorithms for nearest neighbor search with application to vector quantization 显示文摘 | Ramasubramanian V Paliwal K | 1992 | IEEE Trans on Signal Processing1992，40，3： | 1 |
| 17 | Fast Nearest-neighbor search algorithms based on approximation-elimination search显示文摘 | V Ramasubramanian Kuldip K Paliwal | 2000 | Pattern Recognition2000，33，： | 1 |
| 18 | Kinesis: a new approach to replica placement in distributed storage systems显示文摘 | MACCORMICK J MURPHY N RAMASUBRAMANIAN V | 2009 | ACM Transactions on Storage2009，4，4： | 1 |
| 19 | Scanning electron microscopic studies on the hatching of Artemia parthenogenetica cysts 显示文摘 | Ramasubramanian V Munuswamy N | 1993 | Cytobios1993，76，： | 1 |
| 20 | Encoding and recognition of faces based on the human visual model and DCT显示文摘 | D Ramasubramanian Y V Venkatesh | 2001 | Pattern Recognition2001，34，12： | 1 |
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