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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | Systematic review of nutrition screening and assessment in inflammatory bowel disease显示文摘BACKGROUND Malnutrition is prevalent in inflammatory bowel disease (IBD). Multiple nutrition screening (NST) and assessment tools (NAT) have been developed for general populations, but the evidence in patients with IBD remains unclear. AIM To systematically review the prevalence of abnormalities on NSTs and NATs, whether NSTs are associated with NATs, and whether they predict clinical outcomes in patients with IBD. METHODS Comprehensive searches performed in Medline, CINAHL Plus and PubMed. Included: English language studies correlating NSTs with NATs or NSTs/NATs with clinical outcomes in IBD. Excluded: Review articles/case studies;use of body mass index/laboratory values as sole NST/NAT;age<16. RESULTS Of 16 studies and 1618 patients were included, 72% Crohn’s disease and 28% ulcerative colitis. Four NSTs (the Malnutrition Universal Screening Tool, Malnutrition Inflammation Risk Tool (MIRT), Saskatchewan Inflammatory Bowel Disease Nutrition Risk Tool (SaskIBD-NRT) and Nutrition Risk Screening 2002 (NRS-2002) were significantly associated with nutritional assessment measures of sarcopenia and the Subjective Global Assessment (SGA). Three NSTs (MIRT, NRS-2002 and Nutritional Risk Index) were associated with clinical outcomes including hospitalizations, need for surgery, disease flares, and length of stay (LOS). Sarcopenia was the most commonly evaluated NAT associated with outcomes including the need for surgery and post-operative complications. The SGA was not associated with clinical outcomes aside from LOS. CONCLUSION There is limited evidence correlating NSTs, NATs and clinical outcomes in IBD. Although studies support the association of NSTs/NATs with relevant outcomes, the heterogeneity calls for further studies before an optimal tool can be recommended. The NRS-2002, measures of sarcopenia and developments of novel NSTs/NATs, such as the MIRT, represent key, clinically-relevant areas for future exploration. | Suqing Li Michael Ney Tannaz Eslamparast Ben Vandermeer Kathleen P Ismond Karen Kroeker Brendan Halloran Maitreyi Raman Puneeta Tandon | 2019 | World Journal of Gastroenterology2019，25，28： | 9 |
| 3 | Role of computed tomography angiography in detection and staging of small bowel carcinoid tumors显示文摘Small-bowel carcinoid tumors are the most common form(42%) of gastrointestinal carcinoids, which by themselves comprise 70% of neuroendocrine tumors. Although primary small bowel neoplasms are overall rare(3%-6% of all gastrointestinal neoplasms), carcinoids still represent the second most common(20%-30%) primary small-bowel malignancy after small bowel adenocarcinoma. Their imaging evaluation is often challenging. State-of-the-art high-resolution multiphasic computed tomography together with advanced postprocessing methods provides an excellent tool for their depiction. The manifold interactive parameter choices however require knowledge of when to use which technique. Here, we discuss the imaging appearance and evaluation of duodenal, jejunal and ileal carcinoid tumors, including the imaging features of the primary tumor, locoregional mesenteric nodal metastases, and distant metastatic disease. A protocol for optimal lesion detection is presented, including the use of computed tomography enterography, volume acquisition, computed tomography angiography and three-dimensional mapping. Imaging findings are illustrated with a series of challenging cases which illustrate the spectrum of possible disease in the small bowel and mesentery, the range of possible appearances in the bowel itself on multiphase data and extraluminal findings such as the desmoplastic reaction in mesentery and hypervascular liver metastases. Typical imaging pitfalls and pearls are illustrated. | David Bonekamp Siva P Raman Karen M Horton Elliot K Fishman | 2015 | World Journal of Radiology2015，7，9： | 2 |
| 4 | Solubilization of trichloroacetic acid(TCA)precipitated microbial Proteins via NaOH for two-dimensional electrophoresis显示文摘 | Nandaknmar M P Shen J Raman B | 2003 | J Proteome Res2003，2，： | 1 |
| 5 | Syn- thesis of Isoambrettolide and Its Isomers from 1,9-cy- clohexadecadiene显示文摘 | BRAJA D M ROBERT W T RAMAN R P | 1972 | J Org Chem1972，37，24： | 1 |
| 6 | Role of chemokines in tumor growth显示文摘 | Raman D Baugher P J Thu Y M Richmond A | 2007 | Cancer Lett2007，256，： | 1 |
| 7 | Consider NF for membrane separation显示文摘 | Raman L P | 1994 | Chemical engineering progress1994，，4： | 1 |
| 8 | Interpretation of CT and MRI after radiofrequency ablation of hepatic malignancies显示文摘 | Limanond P Zimmerman P Raman SS | 2003 | AJR2003，181，6： | 1 |
| 9 | Intelligent search-based selection of sample points for straightness and flatness estimation显示文摘 | BADAR M A RAMAN S PULAT P S | 2003 | Journal of Manufacturing Science and Engineering2003，125，： | 1 |
| 10 | Synthesis of graphene- muhiwalled carbon nanotubes hybrid nanostructure by strengthened electrostatic interaction and its lithium ion battery application 显示文摘 | Vinayan B P Nagar R Raman V | 2012 | Journal of Materials Chemistry2012，22，19： | 1 |
| 11 | Active and relict sea-floor hydrothermal mineralization at the TAG hydrothermal field, Mid-Atlantic Ridge显示文摘 | Rona P A Hannington M D Raman C V | 1993 | Economic Geology1993，88，： | 1 |
| 12 | A passive solar system for thermal comfort conditioning of building in composite climates 显示文摘 | Raman P Sanjay Mande Kishore V V N | 2000 | Solar Energy2000，70，4： | 1 |
| 13 | Transient hygrothermal stresses in fiber reinforced composites: A heterogeneous characterization approach 显示文摘 | Pavankiran V Toshio N Raman P S | 2003 | Acta Materialia2003，34，： | 1 |
| 14 | Regulation and function of selenoproteins in human disease 显示文摘 | Bellinger F P Raman A V Reeves M A | 2009 | Bio- chemical Journal2009，422，1： | 1 |
| 15 | An airway phantom to standardize CT acquisition in multicenter clinical trials显示文摘 | Robinson TE Long FR Raman P | 2009 | Acad Radiol2009，16，9： | 1 |
| 16 | Inverse analysis for transient moisture diffusion through fiber - reinforced composites 显示文摘 | Pavankiran V Toshhio N Raman P S | 2003 | Acta Materialia2003，51，： | 1 |
| 17 | Chemistry and Biological Activity of Thiazolidinones显示文摘 | Parmar S S Raman K | 1981 | Chem Rev1981，81，： | 1 |
| 18 | Subsurface drain- age to combat waterlogging and salinity in irrigated lands in India: Lessons learned in farmers' fields 显示文摘 | Ritzema H P Satyanarayana T V Raman S | 2008 | Agricultural water manage- ment2008，95，： | 1 |
| 19 | Numerical investigation of possible role of local meteorology in Bhopal gas accident显示文摘 | Boybeyi Z Raman S Zannetti P | 1995 | Atmospheric Environment1995，29，4： | 1 |
| 20 | Deacidification of soybean oil by membrane technology显示文摘 | RAMAN L P CHERYAN M RAJAGOPALAN N | 1996 | Journal of the American Oil Chemists'' Society1996，73，2： | 1 |
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