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| 1 | Biliary strictures complicating living donor liver transplantation:Problems,novel insights and solutions显示文摘Biliary stricture complicating living donor liver transplantation(LDLT) is a relatively common complication, occurring in most transplant centres across the world. Cases of biliary strictures are more common in LDLT than in deceased donor liver transplantation. Endoscopic management is the mainstay for biliary strictures complicating LDLT and includes endoscopic retrograde cholangiography, sphincterotomy and stent placement(with or without balloon dilatation). The efficacy and safety profiles as well as outcomes of endoscopic management of biliary strictures complicating LDLT is an area that needs to be viewed in isolation, owing to its unique set of problems and attending complications; as such, it merits a tailored approach, which is yet to be well established. The diagnostic criteria applied to these strictures are not uniform and are over-reliant on imaging studies showing an anastomotic narrowing. It has to be kept in mind that in the setting of LDLT, a subjective anastomotic narrowing is present in most cases due to a mismatch in ductal diameters. However, whether this narrowing results in a functionally significant narrowing is a question that needs further study. In addition, wide variation in the endotherapy protocols practised in most centres makes it difficult to interpret the results and hampers our understanding of this topic. The outcome definition for endotherapy is also heterogenous and needs to be standardised to allow for comparison of data in this regard and establish a clinical practice guideline. There have been multiple studies in this area in the last 2 years, with novel findings that have provided solutions to some of these issues. This review endeavours to incorporate these new findings into the wider understanding of endotherapy for biliary strictures complicating LDLT, with specific emphasis on diagnosis of strictures in the LDLT setting, endotherapy protocols and outcome definitions. An attempt is made to present the best management options currently available as well as directions for future research in the area. | Harshavardhan B Rao Arjun Prakash Surendran Sudhindran Rama P Venu | 2018 | World Journal of Gastroenterology2018，24，19： | 14 |
| 2 | RANKL/RANK control Brca1 mutation-driven mammary tumors显示文摘 | Verena Sig Kwadwo Owusu-Boaitey Puma A Joshi Anoop Kavirayani Gerald Wimsberger Maria Novatchkova Ivona Kozieradzki Daniel Schramek Nnamdi Edokobi Jerome Hersl Aishia Sampson Ashley Odai-Afotey Conxi Lazaro Eva Gonzalez-Suarez Miguel A Pujaaa for CIMBA Holger Heyn Enrique Vidal Jennifer Cru. ickshank Hal Berman Renu Sarao Melita Tieevic Iris Uribesalgo Luigi Tortola Shuan Rao Yen Tan Georg Pfeiler Eva YHP Lee Zsuzsanna Bago-Horvath Lukas Kenner Helmuth Popper Christian Singer Rama Khokha LaundeRe P Jones Josef M Penninger | 2016 | Cell Research2016，26，7： | 3 |
| 3 | Endoscopic therapy for biliary strictures complicating living donor liver transplantation: Factors predicting better outcome显示文摘AIM To identify factors predicting outcome of endoscopic therapy in bile duct strictures(BDS) post living donor liver transplantation(LDLT).METHODS Patients referred with BDS post LDLT, were retrospectively studied. Patient demographics, symptoms(Pruritus, Jaundice, cholangitis), intra-op variables(cold ischemia time, blood transfusions, number of ducts used, etc.), peri-op complications [hepatic artery thrombosis(HAT), bile leak, infections], stricture morphology(length, donor and recipient duct diameters) and relevant laboratory data both pre-and post-endotherapy were studied. Favourable response to endotherapy was defined as symptomatic relief with > 80% reduction in total bilirubin/serum gamma glutamyl transferase. Statistical analysis was performed using SPSS 20.0.RESULTS Forty-one patients were included(age: 8-63 years). All had right lobe LDLT with duct-to-duct anastomosis. Twenty patients(48.7%) had favourable response to endotherapy. Patients with single duct anastomosis, aggressive stent therapy(multiple endoscopic retrogradecholagiography, upsizing of stents, dilatation and longer duration of stents) and an initial favourable response to endotherapy were independent predictors of good outcome(P < 0.05). Older donor age, HAT, multiple ductal anastomosis and persistent bile leak(> 4 wk post LT) were found to be significant predictors of poor response on multivariate analysis(P < 0.05). CONCLUSION Endoscopic therapy with aggressive stent therapy especially in patients with single duct-to-duct anastomosis was associated with a better outcome. Multiple ductal anastomosis, older donor age, shorter duration of stent therapy, early bile leak and HAT were predictors of poor outcome with endotherapy in these patients. | Harshavardhan B Rao Hasim Ahamed Suprabha Panicker Surendran Sudhindran Rama P Venu | 2017 | World Journal of Gastrointestinal Pathophysiology2017，8，2： | 3 |
| 4 | Development and applications of the reciprocating plate显示文摘 | Lo P C Baird M H I Rama Rao N V | 1992 | Column Chem Eng Commun1992，116，： | 1 |
| 5 | Dynamic coefficient of friction and granular drag force in dense par- ticle flows : Experiments and DEM simulations 显示文摘 | MOYSEY P A RAMA RAO N V BAIRD M H I | 2013 | Powder Technology2013，248，11： | 1 |
| 6 | Electric-field effect on positronium formation and decay in some polymers and fused quartz显示文摘 | Rama Rao M Patro A P Saha P Sen | 1980 | Applied physics1980，22，： | 1 |
| 7 | Hot deformation behavior of Mg-3Al alloy 显示文摘 | SRINIVASAN N PRASAD Y V R K RAMA RAO P | 2008 | Materials Science and Engineering A2008，476，： | 1 |
| 8 | Temporal and spatial variation in TEC using simultaneous measurements from the Indi-an GPS network of receivers during the low solar ac-tivity period of 2004-2005显示文摘 | RAMA RAO P V S GOPI KRISHNA S VARA PRASAD J | 2006 | Ann Geophys2006，24，12： | 1 |
| 9 | Dynamics and temperature dependence of etching processes of porous and barrier aluminum oxide layers 显示文摘 | Dmitri A Brevnov Rama Rao G V Gabriel P Lrpez | 2004 | Electrochemical Acta2004，49，15： | 1 |
| 10 | Lameness in chickens: alliviation by dietary manipulation显示文摘 | Drs S V Rama Rao M V L N Raju R P Sharma | 2003 | Poultry International2003，42，9： | 1 |
| 11 | Effect of support modification by carbon coverage in the dehydro- genation activity of Cu/A1203 catalyst 显示文摘 | Krishna Reddy G Rama Rao K S Kanta Rao P | 1999 | Catal Lett1999，59，： | 1 |
| 12 | Administration of systemic insecticide through root- a new method of control of red palm weevil, Rhynchophorus ferrugineus Fab, in coconut 显示文摘 | Ganeswara Rao A Laxminarayana K Rama Mohan Rao P | 1980 | Indian Coconut Journal1980，11，2： | 1 |
| 13 | Hot de- formation behaviour of Mg-3A1 alloy has been studied u- sing processing map technique 显示文摘 | Srinivasan N Prasad Y V R K Rao P Rama | 2007 | Materials Science and Engineering A2007，476，1： | 1 |
| 14 | AES analysis of fracture toughness variation with heat treatment in an 18 Ni (250 grade)maraging steel显示文摘 | Misra R D K Balasubramanian T V Rama Rao P | 1987 | Journal of Materials Science Letters1987，6，2： | 1 |
| 15 | Hot deformation behaviour of Mg-3A1 alloy---A study using processing map 显示文摘 | SRINIVASAN N PRASAD Y V R K RAMA RAO P | 2008 | Materials Science and Engineering A2008，476，： | 1 |
| 16 | New type of carbon coated alumina supports for the preparation of highly ctive ruthenium catalysts for ammonia synthesis显示文摘 | Rama R K S Rao P K Masthan S K | 1990 | Appl Catal1990，62，1： | 1 |
| 17 | Encapsulation of poly(N-isopropyl acrylamlde) in sihca: A stimuli-responsive porous hybrid material that incorporates molecular nano-valves显示文摘 | Rama Rao G V Lopez G P | 2000 | Adv Mater2000，12，： | 1 |
| 18 | A highly active nano-Ru catalyst supported on novel Mg-A1 hydrotalcite precursor for the synthesis of ammonia显示文摘 | SEETHARAMULU P SIVA KUMAR V PADMASRI A H DAVID RAJU B RAMA RAO K S | 2007 | J Mol Catal A2007，263，12： | 1 |
| 19 | Effect of barium addition on the ammonia synthesis activity of a caesium promoted ruthenium catalyst supported on carbon-covered alumina (CCA)显示文摘 | Rama R K S Masthan S K Rao P K | 1991 | Appl Catal1991，73，1： | 1 |
| 20 | Hydrogenation of nitrobenzene over palladium-supported catalysts-effect of support显示文摘 | Sagar P S Shanthi K Rama Rao K S | 2009 | Applied Catalysis A: General2009，353，2： | 1 |
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