|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Biliary strictures complicating living donor liver transplantation:Problems,novel insights and solutions显示文摘Biliary stricture complicating living donor liver transplantation(LDLT) is a relatively common complication, occurring in most transplant centres across the world. Cases of biliary strictures are more common in LDLT than in deceased donor liver transplantation. Endoscopic management is the mainstay for biliary strictures complicating LDLT and includes endoscopic retrograde cholangiography, sphincterotomy and stent placement(with or without balloon dilatation). The efficacy and safety profiles as well as outcomes of endoscopic management of biliary strictures complicating LDLT is an area that needs to be viewed in isolation, owing to its unique set of problems and attending complications; as such, it merits a tailored approach, which is yet to be well established. The diagnostic criteria applied to these strictures are not uniform and are over-reliant on imaging studies showing an anastomotic narrowing. It has to be kept in mind that in the setting of LDLT, a subjective anastomotic narrowing is present in most cases due to a mismatch in ductal diameters. However, whether this narrowing results in a functionally significant narrowing is a question that needs further study. In addition, wide variation in the endotherapy protocols practised in most centres makes it difficult to interpret the results and hampers our understanding of this topic. The outcome definition for endotherapy is also heterogenous and needs to be standardised to allow for comparison of data in this regard and establish a clinical practice guideline. There have been multiple studies in this area in the last 2 years, with novel findings that have provided solutions to some of these issues. This review endeavours to incorporate these new findings into the wider understanding of endotherapy for biliary strictures complicating LDLT, with specific emphasis on diagnosis of strictures in the LDLT setting, endotherapy protocols and outcome definitions. An attempt is made to present the best management options currently available as well as directions for future research in the area. | Harshavardhan B Rao Arjun Prakash Surendran Sudhindran Rama P Venu | 2018 | World Journal of Gastroenterology2018，24，19： | 14 |
| 2 | RANKL/RANK control Brca1 mutation-driven mammary tumors显示文摘 | Verena Sig Kwadwo Owusu-Boaitey Puma A Joshi Anoop Kavirayani Gerald Wimsberger Maria Novatchkova Ivona Kozieradzki Daniel Schramek Nnamdi Edokobi Jerome Hersl Aishia Sampson Ashley Odai-Afotey Conxi Lazaro Eva Gonzalez-Suarez Miguel A Pujaaa for CIMBA Holger Heyn Enrique Vidal Jennifer Cru. ickshank Hal Berman Renu Sarao Melita Tieevic Iris Uribesalgo Luigi Tortola Shuan Rao Yen Tan Georg Pfeiler Eva YHP Lee Zsuzsanna Bago-Horvath Lukas Kenner Helmuth Popper Christian Singer Rama Khokha LaundeRe P Jones Josef M Penninger | 2016 | Cell Research2016，26，7： | 3 |
| 3 | Endoscopic therapy for biliary strictures complicating living donor liver transplantation: Factors predicting better outcome显示文摘AIM To identify factors predicting outcome of endoscopic therapy in bile duct strictures(BDS) post living donor liver transplantation(LDLT).METHODS Patients referred with BDS post LDLT, were retrospectively studied. Patient demographics, symptoms(Pruritus, Jaundice, cholangitis), intra-op variables(cold ischemia time, blood transfusions, number of ducts used, etc.), peri-op complications [hepatic artery thrombosis(HAT), bile leak, infections], stricture morphology(length, donor and recipient duct diameters) and relevant laboratory data both pre-and post-endotherapy were studied. Favourable response to endotherapy was defined as symptomatic relief with > 80% reduction in total bilirubin/serum gamma glutamyl transferase. Statistical analysis was performed using SPSS 20.0.RESULTS Forty-one patients were included(age: 8-63 years). All had right lobe LDLT with duct-to-duct anastomosis. Twenty patients(48.7%) had favourable response to endotherapy. Patients with single duct anastomosis, aggressive stent therapy(multiple endoscopic retrogradecholagiography, upsizing of stents, dilatation and longer duration of stents) and an initial favourable response to endotherapy were independent predictors of good outcome(P < 0.05). Older donor age, HAT, multiple ductal anastomosis and persistent bile leak(> 4 wk post LT) were found to be significant predictors of poor response on multivariate analysis(P < 0.05). CONCLUSION Endoscopic therapy with aggressive stent therapy especially in patients with single duct-to-duct anastomosis was associated with a better outcome. Multiple ductal anastomosis, older donor age, shorter duration of stent therapy, early bile leak and HAT were predictors of poor outcome with endotherapy in these patients. | Harshavardhan B Rao Hasim Ahamed Suprabha Panicker Surendran Sudhindran Rama P Venu | 2017 | World Journal of Gastrointestinal Pathophysiology2017，8，2： | 3 |
| 4 | Excimer laser intrastromal keratomileusis显示文摘 | Buratto L Ferrari M Rama P | 1992 | Am J Ophthalmol1992，113，3： | 1 |
| 5 | Development and applications of the reciprocating plate显示文摘 | Lo P C Baird M H I Rama Rao N V | 1992 | Column Chem Eng Commun1992，116，： | 1 |
| 6 | Human amniotic membrane transplantation显示文摘 | Franch A Rama P Lambiase A | 1998 | Invest Ophthalmol Vis Sci1998，90，： | 1 |
| 7 | Limbal stem-cell therapy and long-term corneal regeneration显示文摘 | Rama P Matuska S Paganoni G | 2010 | N Engl J Med2010，363，： | 1 |
| 8 | Assimilative capacity and dispersion of pollutants due to industrial sources in Visakhapatnam bowl area显示文摘 | RAMA KRISHNA T V B P S REDDY M K REDDY R C | 2004 | Atmospheric Environment2004，38，39： | 1 |
| 9 | Dynamic coefficient of friction and granular drag force in dense par- ticle flows : Experiments and DEM simulations 显示文摘 | MOYSEY P A RAMA RAO N V BAIRD M H I | 2013 | Powder Technology2013，248，11： | 1 |
| 10 | Bronchoscopic lung volume re- duction in a single-lung transplant recipient with natal lung hyper- inflation: a case report显示文摘 | Pato O Rama P Allegue M | 2010 | Transplant Proe2010，42，5： | 1 |
| 11 | Nonconvulsive status epilepticus 显示文摘 | Rama Maganti Gerber P Drees C | 2008 | Epilepsy & Behavior2008，12，： | 1 |
| 12 | Optimal conductor selection in radial distribution system using plant growth simulation algorithm显示文摘 | Rama P Sivanaga Raju S | 2009 | International Journal of Engineering Studies2009，1，22： | 1 |
| 13 | Limbal stem-cell therapy andlong-term corneal regeneration显示文摘 | Rama P Matuska S Paganoni G | 2010 | N Engl J Med2010，363，2： | 1 |
| 14 | Excimer laser intrastromal keratomileusis显示文摘 | Buratto L Ferrari M Rama P | 1992 | Am J Ophthalmol1992，113，33： | 1 |
| 15 | Vision from the right stem显示文摘 | Pellegrini G Rama P De Luca M | 2011 | Trends Mol Med2011，17，1： | 1 |
| 16 | Deformation and rupture of thin rectangular plates subjected to underwater shock 显示文摘 | Rama K Vendhn C P | 2004 | Impact Eng2004，30，6： | 1 |
| 17 | Adsorptive removal of phthalate ester (di-ethyl phthalate) from aqueous phase by activated carbon: a kinetic study 显示文摘 | Venkata Mohan S Shailaja S Rama Krishna M Sarma P N | 2007 | Journal of Hazardous Materials2007，146，12： | 1 |
| 18 | Electric-field effect on positronium formation and decay in some polymers and fused quartz显示文摘 | Rama Rao M Patro A P Saha P Sen | 1980 | Applied physics1980，22，： | 1 |
| 19 | Biomechanical properties of human and porcine corneas显示文摘 | Elsheikh A Alhasso D Rama P | 2008 | Exp Eye Res2008，86，： | 1 |
| 20 | Hot deformation behavior of Mg-3Al alloy 显示文摘 | SRINIVASAN N PRASAD Y V R K RAMA RAO P | 2008 | Materials Science and Engineering A2008，476，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员