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您的检索式：作者名="Quentin M Anstee"
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| 1 | Role of monocytes and macrophages in experimental and human acute liver failure显示文摘Acute liver failure (ALF) is a devastating clinical syndrome characterised by progressive encephalopathy, coagulopathy, and circulatory dysfunction, which commonly leads to multiorgan failure and death. Central to the pathogenesis of ALF is activation of the immune system with mobilisation of cellular effectors and massive production of cytokines. As key components of the innate immune system, monocytes and macrophages are postulated to play a central role in the initiation, progression and resolution of ALF. ALF in humans follows a rapidly progressive clinical course that poses inherent difficulties in delineating the role of these pivotal immune cells. Therefore, a number of experimental models have been used to study the pathogenesis of ALF. Here we consider the evidence from experimental and human studies of ALF on the role of monocytes and macrophages in acute hepatic injury and the ensuing extrahepatic manifestations, including functional monocyte deactivation and multiple organ failure. | Lucia A Possamai Charalambos Gustav Antoniades Quentin M Anstee Alberto Quaglia Diego Vergani Mark Thursz Julia Wendon | 2010 | World Journal of Gastroenterology2010，16，15： | 12 |
| 2 | 非酒精性脂肪性肝病的问题究竟有多大?显示文摘非酒精性脂肪性肝病(non—alcoholic fatty liver disease,NAFLD)是指排除过量酒精摄入(标准为女性每日〈20g,男性每日〈30g)因素以外的一组肝脏疾病,其中包括单纯性脂肪浸润(肝脂肪变性)、脂肪变性合并炎症(非酒精性脂肪性肝炎,Non—alcoholic steatohepatitis,NASH)及肝硬化。 | Quentin M Anstee Stuart McPherson 高锦洁(译) 夏志伟(校) | 2012 | 英国医学杂志中文版2012，15，4： | 0 |
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