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| 1 | Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation显示文摘AIM To explore the expression of perform andgranzyme B genes mRNA to judge the effect ofimmunosuppression in acute rejection of livertransplantation.METHODS The expression of perform andgranzyme B genes mRNA was examined byreverse transcriptase-polymerase chain reaction(RT--PCR) in hamster to rat liver grafts under theimmunosuppression of cyclosporine or/andsplenectomy. Histological findings were studiedcomparatively.RESULTS Cyclosporine could obviouslydecrease the cellular infiltration, and completelyrepress the expression of mRNA for perform andgranzyme B, but could not change severehepatocyte necrosis and hemorrhage.SPlenectomy could significantly lightenhepatocyte necrosis, and completely eliminatehemorrhage, but not atfect the cellularinfiltration and the expression of perform andgranzyme B genes mRNA. Cyclosporine orsplenectomy alone could not prolong theSurvival time, however, their combination couldcompletely repress the rejection of liver grafts.The survival time of animals were significantlyprolonged (37.1 days ). The architecture ofhepatic lobules was preserved. There was slightcellular infiltration in the portal tracts and noexpression of perform and granzyme B genesmRNA could be seen in three weeks aftertransplantation.CONCLUSION Perform and granzyme B genesare valuable in judging the effect ofimmunosuppression in liver transplantation. | Zhang SG Wu MC Tan JW Chen H Yang JM Qian QJ | 1999 | World Journal of Gastroenterology1999，5，3： | 15 |
| 2 | Recovery of novel bacterial diversity from mangrove sediment显示文摘 | Liang JB Chen YQ Lan CY Tan NFY Zan QJ Huang LN | 2007 | 中国生物学文摘2007，21，7： | 7 |
| 3 | Intraspinal transplantation of CD34+ human umbilical cord blood cells after spinal cord hemisection injury improves functional recovery in adult rats显示文摘 | Zhao,ZM Li,HJ Liu,HY Lu,SH Yang,RC Zhang,QJ Han,ZC | 2005 | 中国生物学文摘2005，19，3： | 2 |
| 4 | Structural elucidation of a neutral fucogalactan from the mycelium of Coprinus comatus显示文摘 | FAN JM ZHANG JS TANG QJ | 2006 | Carbohydr Res2006，341，9： | 1 |
| 5 | Early and delayed cardioprotection of heat stress is mediated by calcitonin gene-related peptide显示文摘 | Song QJ Li YJ Deng HW | 1999 | Naunyn Shmiedebergs Arch Pharmacol1999，359，6： | 1 |
| 6 | Presence and integration of HBV-DNA in mouse oocytes显示文摘 | Huang TH Zhang QJ Xie QD | 2005 | World J Gastroenterol2005，11，： | 1 |
| 7 | miR 181a is an intrinsic rood ulator of T cell sensitivity and selection 显示文摘 | Li QJ Chau J Ebert PJ | 2007 | Cell2007，129，1： | 1 |
| 8 | Altered baseline brain activity in children with ADHD revealed by resting- state functional MRI显示文摘 | Zang YF He Y Zhu CZ Cao QJ Sui MQ Liang M | 2007 | Brain Dev2007，29，2： | 1 |
| 9 | Occupancy and mechanism in antibody- mediated neutralization of animal viruses显示文摘 | Klasse PJ Sattentau QJ | 2002 | J Gen Virol2002，83，9： | 1 |
| 10 | Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis:an updated meta-analysis显示文摘 | Lin ZH Xin YN Dong QJ | | 0，，： | 1 |
| 11 | The Beclinl-VPS34 complex-at the crossroads of autophagy and beyond 显示文摘 | Funderburk SF Wang QJ Yue Z | 2010 | Trends Cell Biol2010，20，： | 1 |
| 12 | Norepinephrine stimulates mobili- zation of endothelial progenitor ceils after limb ischemia 显示文摘 | Jiang QJ Ding SF Wu JX | 2014 | PLoS One2014，9，10： | 1 |
| 13 | Development and validation of the Mandarin speech perception test显示文摘 | Fu QJ Zhu M Wang X | 2011 | J Acoust Soc Am2011，129，6： | 1 |
| 14 | Differential gene expression in vascular smooth muscle cells in primary atherosclerosis and In stent stenosis in humans显示文摘 | Goddard M Shanahan C | 2002 | Arterioscler Thromb Vasc2002，22，： | 1 |
| 15 | Effects of endognous endogenous endothelial interlukin-8 on neutrophil migration across endothelial monolayer显示文摘 | Takahanshin M Masuyan QJ lkeda U | 1995 | CardiovascRes1995，29，： | 1 |
| 16 | Experimental studies onperipheral nerve regeneration enhanced by nerve growth factor显示文摘 | Pang QJ Luo YX Wu YG | 1993 | J Tongji Med Univ1993，13，1： | 1 |
| 17 | The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond显示文摘 | Funderburk SF Wang QJ Yue Z | 2010 | Trends Cell Biol2010，20，6： | 1 |
| 18 | Friction and wear characteristics of lead and its compounds filled PTFE composites under oil lubricated conditions 显示文摘 | ZHANG Z Z XUE QJ LIU W M | 1998 | Tribology International1998，31，7： | 1 |
| 19 | Hyroxyl radical scavenging activity of compatible solutes显示文摘 | Smirnoff N Cumbes QJ | 1989 | Phytochemistry1989，28，4： | 1 |
| 20 | A randomized comparison of percutaneous transluminal coronary angiop1asty by the radial,brachial,and femoral approaches; the access study显示文摘 | Kiemeneij F Laarn1en QJ Odekerken D | 1997 | J Am Coll Cardiol1997，29，6： | 1 |
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