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| 1 | Intracellular tat of human immunodeficiency virus type 1 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus. Role of JAK/STAT signaling显示文摘 | Zeng, Y. Zhang, X. H. Huang, Z. Cheng, L. Yao, S. H. Qin, D. Chen, X. Y. Tang, Q. Lv, Z. G. Zhang, L. Lu, C. | 2007 | 南京医科大学学报(自然科学版)2007，27，5： | 31 |
| 2 | Schistosoma japonicum egg antigens stimulate CD4(+) CD25(+) T cells and modulate airway inflammation in a murine model of asthma显示文摘 | Yang, J. H. Zhao, J. Q. Yang, Y. F. Zhang, L. Yang, X. Zhu, X. Ji, M. J. Sun, N. X. Su,C. | 2007 | 南京医科大学学报(自然科学版)2007，27，4： | 25 |
| 3 | Tissue clearing of both hard and soft tissue organs with the PEGASOS method显示文摘织物空地技术由转织物在 3 尺寸(3-D ) 启用不透明的机关和纸巾的可视化透明。当前的组织空地方法被能与每个单个协议被清除的纸巾的有限类型限制,它不可避免地导致了存在在整个身体或身体部分成像以内盲点。包括骨头和牙齿的难纸巾仍然是要清除的最困难的机关。另外,内长的荧光的损失为基于溶剂的空地方法仍然是一颗主要担心。这里,我们发展了聚乙烯乙二醇(木钉) 联系了溶剂系统(PEGASOS ) ,它将近显示了纸巾的所有类型透明、保存的内长的荧光。骨头和牙齿能被转在变清以后将近不可见。PEGASOS 方法转了透明的整个成年老鼠身体,我们对一个成年老鼠头骨头,牙齿,大脑,肌肉,和其它填写了的图象有能力没有盲目区域的纸巾。难织物透明性使我们能重建在 3-D 的未经触动的上颚,牙齿,腿节,或膝关节。另外,我们在长距离上在亚 cellular 分辨率并且到踪迹个人神经原和轴突管理了未经触动的鼠标大脑到图象。我们也通过 vertebrae 直接设想了背面的根中心。最后,我们在长骨头的髓空间以内在 3-D 揭示了神经网络的分发模式。这些结果建议 PEGASOS 方法是为一般生物医学的研究的一个有用工具。 | Dian Jing Shiwen Zhang Wenjing Luo Xiaofei Gao Yi Men Chi Ma Xiaohua Liu Yating Yi Abhijit Bugde Bo O. Zhou Zhihe Zhao Quan Yuan Jian Q. Feng Liang Gao Woo-Ping Ge Hu Zhao | 2018 | Cell Research2018，28，8： | 18 |
| 4 | TiZr-base Bulk Metallic Glass with over 50 mm in Diameter显示文摘Low-cost TiZr-base bulk metallic glasses(BMGs)(Ti36.1Zr33.2Ni5.8Be24.9)100-xCux(x=5,7 and 9) with a maximum size of over 50 mm in diameter were developed by optimizing the alloy composition.The idea is initiated by selecting a particular microstructure comprising primary β-Ti dendrite and amorphous phase.Afterwards,based on this composition of amorphous phase,a class of TiZr-base bulk metallic glasses was designed step by step to reach the optimum composition range.The glass transition temperature(Tg),initial crystallization temperature(Tx) and width of supercooled region(△T) of(Ti36.1Zr33.2Ni5.8Be24.9)91Cu9 BMG are 611,655 and 44 K,respectively.The(Ti36.1Zr33.2Ni5.8Be24.9)91Cu9 BMG exhibits low density of 5.541 g·cm-3 and high compressive fracture strength of 1800 MPa,which promises the potential application as structural materials. | M. Q. Tang H.F. Zhang Z. W. Zhu H.M. Fu A.M. Wang H. Li Z.Q. Hu | 2010 | Journal of Materials Science & Technology2010，26，6： | 17 |
| 5 | Self-Assembly and Photocatalysis of Mesoporous TiO2 Nanocrystal Clusters显示文摘有大表面区域和提高的 photocatalytic 活动的锐钛矿 TiO2 的 Mesoporous nanocrystal 簇成功地被综合了。合成包含进亚微米簇,有硅石层的这些簇的涂层,移开器官的 ligands 并且改进簇的 crystallinity 的热处理,和暴露 mesoporous 催化剂的最后搬迁的硅石的恐水病的 TiO2 nanocrystals 自己组装。在硅石涂层的帮助下,簇不仅维持他们的小谷物尺寸而且在高温度在锻烧以后保留他们的 mesoporous 结构(与象 277 m2/g 一样高的赌注表面区域) 。蚀刻 SiO2 也导致在水里有高 dispersity 的簇。我们能识别最佳的锻烧温度生产拥有高 crystallinity 和大表面区域的 TiO2 nanocrystal 簇,因此由紫外光在照明下面在器官的分子的分解显示出优秀催化效率。与氮的方便的做在可见的光和自然日光把这些 nanocrystal 簇变换成活跃光催化剂。用 nanocrystals 形成明确的 mesoporous 簇的策略为与提高的活动和稳定性设计光催化剂答应一个万用、有用的方法。 | Qiao Zhang Ji-Bong Joo Zhenda Lu Michael Dahl Diana Q. L. Oliveira Miaomiao Ye Yadong Yin | 2011 | Nano Research2011，4，1： | 17 |
| 6 | Interactions of IL-12A and IL-12B Polymorphisms on the Risk of Cervical Cancer in Chinese Women显示文摘 | Chen, X. J. Han, S. P. Wang, S. N. Zhou, X. Y. Zhang, M. F. Dong, J. Shi, X. Y. Qian, N. F. Wang, X. R. Wei, Q. Y. Shen, H. B. Hu, Z.B. | 2009 | 南京医科大学学报(自然科学版)2009，29，3： | 16 |
| 7 | RESEARCH AND DEVELOPMENT OF HIGH TEMPERATURESTRUCTURAL MATERIALS FOR AERO-ENGINE APPLICATIONS显示文摘The status of research, development of superalloys and materials processing & fabrication technologies for aero-engine applications in China Aviation Industry, with an emphasis on recent achievements at BIAM including directionally solidified and single crystal superalloys for blade and vane applications, wrought superalloys for aero-engine disks and rings, and powder metallurgy (PM) superalloys for high performance disk applications were described. It was also reviewed the development of new class of high temperature structural materials, such as structural intermetallics, and advanced material processing technologies including rapid solidification, spray forming and so on. The trends of research and development of the above mentioned superalloys and processing technologies are outlined. Cast, wrought and PM superalloys are the workhorse materials for the hot section of current aero-engines. New high temperature materials and advanced processing technologies have been and will be the subject of study. It is speculated that high performance, high purity and low cost superalloys and technologies will play key roles in aero-engines. | G. Q. Zhang | 2005 | Acta Metallurgica Sinica(English Letters)2005，18，4： | 15 |
| 8 | Contamination by Organochlorine Pesticides in the Estuaries of Southeast China显示文摘Persistent organic pollutants(POPs) such as organochlorine pesticides are of global concern due to their widespread occurrence and persistence. This paper reports recent research studying the distribution and fate of organochlorine pesticides in the Jiulong River, the Minjiang River and the Pearl River estuaries in Southeast China. Eighteen organochlorine pesticides were extracted from water, pore water and sediment samples, followed by analysis by GC ECD. The results showed that the contamination levels were similar in these three estuaries. The levels of the total organochlorine pesticides in porewater were significantly higher than those in surface water, due to the high affinity of these hydrophobic compounds for sediment phase. Among the hexachlorocyclohexane(HCH) compounds, β HCH was found to be the most important isomer. The analysis of 1,1,1 trichloro 2,2 bis chlorophenyl ethane(DDT) and its metabolites showed that 1,1 dichloro 2[ o chlorophenyl] 2[ p chlorophenyl] ethylene(DDE) was dominant in the group. | Z. L. Zhang 1,2 , H. S. Hong 2, J. L. Zhou 3,** , M. H. Dai 2, K. Maskaouib 2 and W. Q. Chen 2 1. Department of Environmental Science and Engineering, Tsinghua POPs Research Centre, Tsinghua University, Beijing 100084, China 2. Key Laborator | 2002 | Chemical Research in Chinese Universities2002，18，2： | 13 |
| 9 | INFLUENCE OF NaCl DEPOSITION ON ATMOSPHERIC CORROSION OF A3 STEEL IN THE PRESENCE OF SO_2显示文摘The regularities of atmospheric corrosion of A3 steel deposited with different amountof NaCl exposed to the air containing 1ppm SO2 at 80% RH and 25℃ were studied inlaboratory. NaCl can accelerate the corrosion of A3 steel obviously under such con-dition. The relationship between the weight loss of A3 steel and the amount of NaCldeposition can be well described by using a quadratic function. Fourier transform in-frared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopyand electron dispersion X-ray analysis (SEM/EDAX) were used to characterize thecorrosion products. In the absence of NaCl, FeSO4 xH2O is the dominant corro-sion products, while Fe3O4, FeSO4@ H2O, β-FeOOH and γ-FeOOH dominate in thepresence of NaCl. | Q. Qu, C.W. Yan, L. Zhang , Y. Wan and C.N. CaoState Key Laboratory for Corrosion and Protection, Institute of Metal Research, The Chinese Academy of Sciences, Shenyang 110016, ChinaDepartment of Chemistry, Yunnan University, Kunming 650091, ChinaSchool of Chemical Science and Engineering, Liaoning University, Shenyang 110036, China | 2002 | Acta Metallurgica Sinica(English Letters)2002，15，5： | 13 |
| 10 | Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke显示文摘 | Luo, C. X. Jiang, J. Zhou, Q. G. Zhu, X. J. Wang, W. Zhang, Z. J. Han, X. Zhu, D. Y. | 2007 | 南京医科大学学报(自然科学版)2007，27，10： | 13 |
| 11 | Progress of applied research on TiO_2 photocatalysis-membrane separation coupling technology in water and wastewater treatments显示文摘Photocatalysis-membrane separation coupling technology has been a heavily researched area in water and wastewater treatment during recent years. The membrane separation process allows the photocatalyst to be easily separated, recovered and reused. More significantly, the membrane is efficient to maintain high flux of membranes as the photocatalyst can reduce the membrane fouling problem which is a hindrance in the development of membrane process. Moreover, some synergistic effects can also be produced, and thus the efficiency of water treatment is enhanced greatly. A comprehensive review of photocatalysis-membrane separation coupling technology is conducted with an insight into its configurations, theories involved, characteristics, and factors that influ-ence the coupling technology. In view of the existing problems, the prospects for future development are also proposed. | XIAO YuTang XU ShuangShuang LI ZhiHua AN XiaoHong ZHOU Lei ZHANG YongLai FU Q. Shiang | 2010 | Chinese Science Bulletin2010，55，14： | 13 |
| 12 | STUDY ON THE PREDICTIVE METHOD OF BUCKLING DEFORMATIONS OF THIN-PLATE WELDED STRUCTURES显示文摘The buckling formation and influence factors during welding thin - plated structures were investigated based on finite element methods, An engineering treatment method for prdicating the buckling distor- tion was proposed in here. It was used the equivalent applied thermal - load to simulate the welding residual stress,therefore the calculation of complex welding distoriton can be transformed into 3D elas- tic structural applied- load analyses, which can reduce the quantities of calculating works effectively. The validation of the method was verified by comparison of the numerical simulation and experimental results. The simulation of buckling distorition for side - walled structrues of paseenger train was per- formed and the calculation was in agreement with measuring results in general. It was shown that the main factors for producing the buckling were the intermittent fillet and ping the during welding the stiffened beams and columns to the panel.The existence of the free edge of panels would reduce the crit- ical buckling stress and enlarge the deflection obviously,but the continuous weld in closed frames didn’ t degrade the buckling situation. | X. Q. Yang L. X. Huo Y. F. Zhang and J. X. Yan (School of Material Science and Engineering, Tianjin University, Tianjin 300072, China) | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，1： | 13 |
| 13 | Vagal Nerve Stimulation May Be a Potentially Beneficial Treatment for Acute Myocardial Ischemia显示文摘 | J. Xiong F. S. Xue Y. J. Yuan Q. Wang S. Li J. H. Liu X. Liao Y. M. Zhang | 2010 | 麻醉与监护论坛2010，17，5： | 10 |
| 14 | Infection of hepatitis B virus in extrahepatic endothelial tissues mediated by endothelial progenitor cells显示文摘 | Rong, Q. F. Huang, J. Su, E. B. Li, J. Li, J. Y. Zhang, L. L. Cao, K. J. | 2007 | 南京医科大学学报(自然科学版)2007，27，10： | 9 |
| 15 | Hsa-miR-1246, hsa-miR-320a and hsa-miR-196b-5p inhibitors can reduce the cytotoxicity of Ebola virus glycoprotein in vitro显示文摘Ebola virus(EBOV)causes a highly lethal hemorrhagic fever syndrome in humans and has been associated with mortality rates of up to 91%in Zaire,the most lethal strain.Though the viral envelope glycoprotein(GP)mediates widespread inflammation and cellular damage,these changes have mainly focused on alterations at the protein level,the role of microRNAs(miRNAs)in the molecular pathogenesis underlying this lethal disease is not fully understood.Here,we report that the miRNAs hsa-miR-1246,hsa-miR-320a and hsa-miR-196b-5p were induced in human umbilical vein endothelial cells(HUVECs)following expression of EBOV GP.Among the proteins encoded by predicted targets of these miRNAs,the adhesion-related molecules tissue factor pathway inhibitor(TFPI),dystroglycan1(DAG1)and the caspase 8 and FADD-like apoptosis regulator(CFLAR)were significantly downregulated in EBOV GP-expressing HUVECs.Moreover,inhibition of hsa-miR-1246,hsa-miR-320a and hsa-miR-196b-5p,or overexpression of TFPI,DAG1 and CFLAR rescued the cell viability that was induced by EBOV GP.Our results provide a novel molecular basis for EBOV pathogenesis and may contribute to the development of strategies to protect against future EBOV pandemics. | SHENG MiaoMiao ZHONG Ying CHEN Yang DU JianChao JU XiangWu ZHAO Chen ZHANG GuiGen ZHANG LiFang LIU KangTai YANG Ning XIE Peng LI DangSheng ZHANG Michael Q. JIANG ChengYu | 2014 | Science China(Life Sciences)2014，57，10： | 7 |
| 16 | DEFORMATION AND FRACTURE MECHANISMS OF TWO-PHASE TiAl-BASED ALLOYS WITH FULLY LAMELLAR MICROSTRUCTURE显示文摘DEFORMATIONANDFRACTUREMECHANISMSOFTWO-PHASETiAl-BASEDALLOYSWITHFULLYLAMELLARMICROSTRUCTUREY.G.Zhang,C.Q.Chen(BeijingUniversit... | Y. G .Zhang, C. Q. Chen (Beijing University of Aeronautics and Astronautics, Beijing 100083, China)Q. Xu (Beijing Laboratory of Electron Microscopy, Chinese Academy of Sciences. Beijing,China)M. C. Chaturvedi (The University of Manitoba, Winnipeg, Manito | 1995 | Acta Metallurgica Sinica(English Letters)1995，8，Z1： | 7 |
| 17 | Population dynamics of cancer cells with cell state conversions显示文摘 | Da Zhou Dingming Wu Zhe Li Minping Qian Michael Q. Zhang | 2013 | Frontiers of Electrical and Electronic Engineering in China2013，8，3： | 6 |
| 18 | SIMULATION OF VIBRATION STRESS RELIEF AFTER WELDING BASED ON FEM显示文摘一个有限元素模型在 welding.For 以后为颤动压力地势( VSR )的模拟被开发 nonresonant 颤动,在应力的减小强烈取决于 vibration.For 的振幅反响的颤动,颤动频率是钥匙因为压力 relief.The 颤动频率应该为需要的颤动接近结构天赋频率 mode.Only 小的颤动振幅被要求,它将在时间没有的 vibration.Vibration 期间被放大主要 | X.C. Zhao Y.D. Zhang H.W. Zhang Q. Wu | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，4： | 6 |
| 19 | FRACTAL RESEARCH ON CRACKS PROPAGATION OF GAS PIPELINE X52 STEEL WELDING LINE UNDER HYDROGEN ENVIRONMENT显示文摘Based on the theory of hydrogen enhanced localized plasticity of the hydrogen induced cracking and considered the effect of residual stress produced by eliminated stress heat treatment, a fractal model of hydrogen induced cinching was presented, and a relationship among the effective surface energy (H), fractal dimension D and stress intensity factor of hydrogen induced cracking, KIH, for welding pipeline under hydrogen environment was set up, from which the relationship of D and KISCC is obtained. The model was verified experimentally to be correct. | S.H. Dong , Y.M. Lu, Y. Zhang and Q. Wu (Mechanics Electronic Department, University of Petroleum, Beijing 102200, China) (Department of Material Physics, University of Science and Technology Beijing, Beijing 100083, China) (Yan Shan University, Qinhuangd | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，3： | 5 |
| 20 | A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction显示文摘 | Yin, L. Chung, C. M. Huo, R. Liu, H. Zhou, C. Xu, W. Zhu, H. Zhang, J. Shi, Q. Wong, H. Y.C. Chen, J. Lu, Y. Bi, Y. Zhao, C. Du, Y. Ma, M. Cai, Y. Chen, W. Y. Fok, K. L. Tsang, L. L. Li, K. Ni, Y. Chung, Y. W. Zhou, Z. Sha, J. Chan, H. C. | 2009 | 南京医科大学学报(自然科学版)2009，29，4： | 5 |
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