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16篇 您的检索式:作者名="Pullan M"
    题名 作者 年代 出处 被引量
1Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity显示文摘One of the major aims of the International Union of Physiological Sciences (IUPS) Physiome Project is to develop multiscale mathematical and computer models that can be used to help understand human health. We present here a small facet of this broad plan that applies to the gastrointestinal system. Specifically, we present an anatomically and physiologically based modelling framework that is capable of simulating normal and pathological electrical activity within the stomach and small intestine. The continuum models used within this framework have been created using anatomical information derived from common medical imaging modalities and data from the Visible Human Project. These models explicitly incorporate the various smooth muscle layers and networks of interstitial cells of Cajal (ICC) that are known to exist within the walls of the stomach and small bowel. Electrical activity within individual ICCs and smooth muscle cells is simulated using a previously published simplified representation of the cell level electrical activity. This simulated cell level activity is incorporated into a bidomain representation of the tissue, allowing electrical activity of the entire stomach or intestine to be simulated in the anatomically derived models. This electrical modelling framework successfully replicates many of the qualitative features of the slow wave activity within the stomach and intestine and has also been used to investigate activity associated with functional uncoupling of the stomach.Leo K Cheng Rie Komuro Travis M Austin Martin L Buist Andrew J Pullan 2007World Journal of Gastroenterology2007,13,9:3
2Ge- nome-wide analysis of the role of GlnR in Strepto- myces venezuelae provides new insights into global nitrogen regulation in actinomycetes显示文摘Pullan ST Chandra G Bibb M J 2011BMC Ge- nomies2011,12,1:1
3Validation of EuroSCORE 11 in a modern cohort of patients undergoing cardiac surgery 显示文摘Chalmers J Pullan M Fabri B McShane J Shaw M Mediratta N 2013Eur J Cardiothorac Surg2013,43,:1
4Origins and Struc- ture of Spike-Type Rotating Stall显示文摘Pullan G Young A M Day I J 2015Journal of Tur- bomachinery2015,137,5:1
5Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes显示文摘PULLAN S T CHANDRA G BIBB M J 2011BMC Genomics2011,12,:1
6An experimental and computational study of the formation of a streamwise shed vortex in a turbine stage显示文摘Pullan G Denton J D Dunkley M J 2003ASME Journal of Turbomachinery2003,125,2:1
7An algorithm for a class of continuous linear programs显示文摘PULLAN M C 1993SIAM J Control Optim1993,31,:1
8Forms of optimal solutions for separated continuous linear programs显示文摘PULLAN M C 1995SIAM J Control Optim1995,33,:1
9Linear optimal control problems with piecewise analytic solutions显示文摘PULLAN M C 1996J Math Anal Appl1996,197,:1
10Convergence of a general class of algorithms for separated continuous linear programs显示文摘PULLAN M C 2000SIAM J Optim2000,10,:1
11An extended algorithm for separated continuous linear programs显示文摘PULLAN M C 2002Math Program2002,93,:1
12Cardiac electrical activity-from heart to body surface and back again 显示文摘Pullan A J Buist M L Sands G B 2003J Electrocardiol2003,36,:1
13Validation of EuroSCORE Ⅱ in a modern cohort of patients undergoing cardiac surgery显示文摘Chalmers J Pullan M Fabri B 2013Eur J Cardiothorac Surg2013,43,4:1
14BarraCUDA-a fast short read sequence a- ligner using graphics processing units显示文摘Klus P Lam S Lyberg D Cheung M S Pullan G McFarlane I Yeo GSh Lain B Y 2012BMC Research Notes2012,5,:1
15Linear optimal control problems with piecewise analytic solutions显示文摘PULLAN M C 1996Journal of Mathemati- cal Analysis and Applications1996,197,1:1
16Bridging annuloplasty for left atrioventricular valve of partial atrioventricular septal defect显示文摘Srinivasan A K Graysom A D Pullan D M 0,,01:1
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