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6篇 您的检索式：作者名="Pullan L"

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		题名	作者	年代	出处	被引量
	1	Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity显示文摘One of the major aims of the International Union of Physiological Sciences (IUPS) Physiome Project is to develop multiscale mathematical and computer models that can be used to help understand human health. We present here a small facet of this broad plan that applies to the gastrointestinal system. Specifically, we present an anatomically and physiologically based modelling framework that is capable of simulating normal and pathological electrical activity within the stomach and small intestine. The continuum models used within this framework have been created using anatomical information derived from common medical imaging modalities and data from the Visible Human Project. These models explicitly incorporate the various smooth muscle layers and networks of interstitial cells of Cajal (ICC) that are known to exist within the walls of the stomach and small bowel. Electrical activity within individual ICCs and smooth muscle cells is simulated using a previously published simplified representation of the cell level electrical activity. This simulated cell level activity is incorporated into a bidomain representation of the tissue, allowing electrical activity of the entire stomach or intestine to be simulated in the anatomically derived models. This electrical modelling framework successfully replicates many of the qualitative features of the slow wave activity within the stomach and intestine and has also been used to investigate activity associated with functional uncoupling of the stomach.	Leo K Cheng Rie Komuro Travis M Austin Martin L Buist Andrew J Pullan	2007	World Journal of Gastroenterology2007，13，9：	3
	2	A semi-analytic boundary element method for parabolic problems 显示文摘	Brunton I L Pullan A J	1996	Engineering Analysis with Boundary Elements1996，18，4：	1
	3	Cardiac electrical activity-from heart to body surface and back again 显示文摘	Pullan A J Buist M L Sands G B	2003	J Electrocardiol2003，36，：	1
	4	The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter显示文摘	Gohlke U Pullan L McDevitt C A	2005	Proc Natl Acad Sci USA2005，102，10：	1
	5	Global numbers of infection and disease burden of soil transmitted helminth infections in 2010显示文摘	Pullan R L Smith J L Jasrasaria R	2014	Parasit Vectors2014，7，1：	1
	6	Modelling gastrointestinal bioelectric activity 显示文摘	Pullan A Cheng L Yassi R	2004	Prog Biophys Mol Bio2004，85，23：	1

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