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38篇 您的检索式:作者名="Puhlmann"
    题名 作者 年代 出处 被引量
1Growth of Hg1-xMnxTe Crystals by the Travelling Heater Method显示文摘Gille P R?ssner U Puhlmann N 1995Emiconductor Science and Technology1995,10,:1
2Generation of a recombinant oncolytic Newcastle disease virus and expression of a full IgG antibody from two transgenes显示文摘Puhler F Willuda J Puhlmann J Mumberg D Romer-Oberdorfer A Beier R 2008Gene Ther2008,15,5:1
3Generation of a recombinant oncolytic Newcastle disease virus and expression of a full IgG antibody from two transgenes 显示文摘Puhler F Willuda J Puhlmann J 2008Gene Ther2008,15,5:1
4Vaccinia as a vector for tumor-directed gene therapy:biodistribution of a thymidine kinase-deleted mutant显示文摘Puhlmann M Brown C Gnant M 2000Cancer Gene Ther2000,7,1:1
5Gewinnung von immunologisch aktiven polysacchariden aus Echinacea-Drogen und-Gewebekulturen 显示文摘Wagner H Stuppner H Puhlmann J 1989ZPhytother1989,10,:1
6Systemic administration of a recombinant vaccinia virus expressing the cytosine deaminase gene and subsequent treatment with 5-fluorocytosine leads to tumor-specific gene expression and prolongation of survival in mice显示文摘Gnant MF Puhlmann M Alexander HR 1999Cancer Res1999,59,:1
7Immunologische in - vivo and in- vitro studies on Echinacea extracts显示文摘Bauer VR Jurcic K Puhlmann J 1988Arzneimittel -Forschung/ Drug Res1988,38,2:1
8Differential effects of short-term growth hormone therapy on the cardiovascular risk profile in patients with chronic kidney disease: a pilot study 显示文摘Fischer DC Nissel R Puhlmann A 2009Clin Nephrol2009,72,5:1
9Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression显示文摘Mc Cart JA Puhlmann M Lee J 2000Gene Therapy2000,7,14:1
10Interleukin-lbeta in- duced vascular permeability is dependent on induction of endotheli- al tissue factor activity显示文摘Puhlmann M Weinreich DM Farina JM 2005J Transl Med2005,3,:1
11Impact of the cyclooxygenase systerm on doxorubicin-induced functional multidrug resisitance overexpression and doxorubicin sensitivity in acute myeloid leulemic HL-60 Cells 显示文摘Puhlmann U Ziemann C Ruedell G 2005J Pharmacol Exp Ther2005,312,1:1
12Vaccinia as a vec- tor for tumor-directed gene therapy: biodistribntion of a thymi- dine kinase-deleted mutant显示文摘Puhlmann M Brown C K Gnant M 2000Cancer Gene Ther2000,7,:1
13Thymidine kinase-deleted vaccinia virus expressing purine nucleoside phosphorylase as a vector for tumor-directed gene therapy显示文摘Puhlmann M Gnant M Brown CK 1999Hum Gene Ther1999,10,4:1
14Parameter uncertainty and identifiability of a conceptual semi-distributed model to simulate hydrological processes in a small headwater catchment in Northwest China显示文摘Introduction:Conceptual hydrological models are useful tools to support catchment water management.However,the identifiability of parameters and structural uncertainties in conceptual rainfall-runoff modeling prove to be a difficult task.Here,we aim to evaluate the performance of a conceptual semi-distributed rainfall-runoff model,HBV-light,with emphasis on parameter identifiability,uncertainty,and model structural validity.Results:The results of a regional sensitivity analysis(RSA)show that most of the model parameters are highly sensitive when runoff signatures or combinations of different objective functions are used.Results based on the generalized likelihood uncertainty estimation(GLUE)method further show that most of the model parameters are well constrained,showing higher parameter identifiability and lower model uncertainty when runoff signatures or combined objective functions are used.Finally,the dynamic identifiability analysis(DYNIA)shows different types of parameter behavior and reveals that model parameters have a higher identifiability in periods where they play a crucial role in representing the predicted runoff.Conclusions:The HBV-light model is generally able to simulate the runoff in the Pailugou catchment with an acceptable accuracy.Model parameter sensitivity is largely dependent upon the objective function used for the model evaluation in the sensitivity analysis.More frequent runoff observations would substantially increase the knowledge on the rainfall-runoff transformation in the catchment and,specifically,improve the distinction of fast surface-near runoff and interflow components in their contribution to the total catchment runoff.Our results highlight the importance of identifying the periods when intensive monitoring is critical for deriving parameter values of reduced uncertainty.Shuai Ouyang Heike Puhlmann Shunli Wang Klaus von Wilpert Osbert Jianxin Sun 2014Ecological Processes2014,3,1:1
15Generation of a recombinant oncolytic Newcastle disease virus and expression of a full IgG antibody from two transgenes显示文摘Ptihler F Willuda J Puhlmann J 2008Gene Ther2008,15,5:1
16Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression 显示文摘McCart JA Puhlmann M Lee J 2000Gene Ther2000,7,14:1
17Generation of a recombinant oncolytic Newcastle disease virus and expression of a full IgG antibody from two transgenes显示文摘Puhler F Willuda J Puhlmann J 2008Gene Ther2008,15,5:1
18Effect of interleu- kin 1 receptor antagonist gene transduetion on human melanoma xenografts in nude mice 显示文摘Weinreich DM Elaraj DM Puhlmann M 2003Cancer Res2003,63,18:1
19Modelling the carbon budget of intensive forest monitoring sites in Germany using the simulation model BIOME BGC显示文摘Jochheim H Puhlmann M Beese F 2009iForest2009,,2:1
20Vaccinia as a vector for tumor-drected gene therapy:Biodistribution of a thymidine kinase-deleted mutant显示文摘Puhlmann M Brown CK Gnant M 2000Cancer Gene Ther2000,7,1:1
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