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81篇 您的检索式:作者名="Pritsch"
    题名 作者 年代 出处 被引量
1Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy.Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz 2010World Journal of Gastroenterology2010,16,8:10
2Renal Cell Carcinoma With Tumor Thrombus Extension Into the Vena Cava: Prospective Long-Term Followup显示文摘Axel Haferkamp Patrick J. Bastian Hildegard Jakobi Maria Pritsch Jesco Pfitzenmaier Peter Albers Peter Hallscheidt Stefan C. Müller Markus Hohenfellner 2007The Journal of Urology2007,,5:2
3Molecular cloning:a laboratory manual显示文摘Samrook J Pritsch EF Maniatis T 1990Analytical Biochemistry1990,186,:1
4Monteggia and equivalent lesions:a study of 41 cases显示文摘Givon U Pritsch M Levy O 0,,337:1
5Two incision synovec- tomy and radiation treatment for diffuse pigmented villonodular synovitis of the knee with extra-articular component 显示文摘Wu CC Pritsch T Bickels J 2007Knee2007,14,2:1
6A randomized clinical trialcomparing the impact of different oral hygiene protocols andsealant applications on plaque, gingival, and caries index scores显示文摘Zingler S Pritsch M Wrede DJ 2014Eur J Orthod2014,36,2:1
7A wide and versatile combined surgical approach to the shoulder 显示文摘Levy O Pritsch M Oran A eta/ 1999J Shoulder Elbow Surg1999,8,5:1
8Antefior cruciate ligament injures显示文摘Haim A Pritsch T Yosepov L 2006Harefuah2006,145,3:1
9Upper limb kinematics af- ter arthroscopic and open shoulder stabilization显示文摘Uri O Pritsch M Oran A 2014Shoulder and Elbow Surgery2014,24,39:1
10Functional and comparative bioinformatic analysis of expressed genes from wheat spikes infected with Fusarium graminearum显示文摘Kruger W M Pritsch C Chao S M 2002Molecular Plant-Microbe Interaction2002,15,5:1
11Xerocomus badius-Picea abies, an ectomycorrhiza of high activity and element storage capacity in acidic soil显示文摘Kottke I Qian X M Pritsch K 1998Mycorrhiza1998,7,:1
12Mueller reinforcement rings in acetabular revision:outcome in 164 hips followed for 2-17 years显示文摘Schlegel UJ Bitsch RG Pritsch M 2006Acta Orthop2006,2,:1
13Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning 显示文摘Pritsch B Reis J Martinowich K 2010Neuron2010,66,:1
14Characterization and identification of black alder ectomycorrhizas by PCR/RFLP analyses of the rDNA internal transcribed spacer(ITS)显示文摘Pritsch K boyle H Munch J C 1997New Phytol1997,137,:1
15Interstitial fibrosis in the heart:differences in extracellular matrix proteins and matrix metalloproteinases in end-stage dilated,ischaemic and valvular cardiomyopathy显示文摘Herpel E Pritsch M Koch A 0,,:1
16Two incision synovectomy and radiation treatment for diffuse pigmented villonodular synovitis of the knee with extra-articular component显示文摘Chia-Chun Wu Tamir Pritsch Jacob Bickels Tierney Wienberg Martin M. Malawer 2006The Knee2006,,2:1
17Recurrent soil freeze-thaw cycles enhance grassland productivity 显示文摘KREYL1NG J BEIERKUHNLEIN C PRITSCH K 2008New Phytology2008,177,4:1
18A rapid and highly sensitive method for measuring enzyme activities in single mycorrhizal tips using 4-methylumbelliferone-labelled fluoro- genic substrates in a microplate system 显示文摘Pritsch K Raidl S Marksteiner E 2004Journal of Mi- crobiological Methods2004,58,:1
19Enzyme secretion by ECM fungi and exploitation of mineral nutrients from soil organic matter显示文摘Pritsch K Garbaye J 2011Annals of Forest Science2011,68,1:1
20Minimal residual disease detection in B-cell malignanciesby assessing IgH rearrangement显示文摘K. Maloum O. Pritsch G. Dighiero 1997Hematology and Cell Therapy1997,,3:1
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