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| 1 | Predictors of esophageal varices and first variceal bleeding in liver cirrhosis patients显示文摘AIM To assess 'predictors' of esophageal varices(EV) and variceal bleeding using non-invasive markers in Albanian patients diagnosed with liver cirrhosis.METHODS One hundred thirty-nine newly diagnosed cirrhotic patients without variceal bleeding were included in this analysis. Model for end-stage liver disease(MELD), aspartate aminotransferase(AST) to alanine aminotransferase(ALT) ratio(AST/ALT), AST to platelet ratio index(APRI), platelet count to spleen diameter(PC/SD), fibrosis-4-index(FIB-4), fibrosis index(FI) and King's Score were measured for all participants. All patients underwent endoscopic assessment within two days of hospitalization. The major end point was the first esophageal variceal bleeding(EVB) event. The diagnostic performance of 'predictors' for the presence of EV and EVB were assessed by sensitivity and specificity values obtained from the receiver operating characteristics procedure.RESULTS FIB-4 was the only strong and significant 'predictor' of esophageal varices(multivariable-adjusted OR = 1.57 for one unit increment; 95%CI: 1.15-2.14). Furthermore, a cut-off value of 3.23 for FIB-4 was a significant predictor of esophageal varices, with a sensitivity of 72%, a specificity of 58% and a proportion of area under the curve(AUC) of 66%(P = 0.01). During the follow-up(median: 31.5 mo; interquartile range: 11-59 mo), 34 patients(24%) experienced a first EVB. FIB-4 was a poor predictor of EVB(the AUC was only 51%) for a cut-off value of 5.02. Furthermore, the AUC of AST/ALT, APRI, PC/SD, FI, MELD and King's Score ranged from 45% to 55%. None of the non-invasive markers turned out to be a useful predictor of EVB.CONCLUSION Despite the low diagnostic accuracy, FIB-4 appears the most efficient non-invasive liver fibrosis marker which can be used as an initial screening tool for cirrhotic patients. | Bledar Kraja Iris Mone Ilir Akshija Adea Kocollari Skerdi Prifti Genc Burazeri | 2017 | World Journal of Gastroenterology2017，23，26： | 40 |
| 2 | Epidemiology of hepatitis B virus infection in Albania显示文摘AIM:To assess the prevalence and socio-demographic distribution of hepatitis B virus(HBV) infection in Albania.METHODS:Blood samples from 410 unselected schoolboys,666 students,500 military personnel,1286 casual blood donors,378 voluntary blood donors and 640 pregnant women(total 3880 non-vaccinated residents of rural and metropolitan areas from all over Albania;2354(60.7%) male and 1526(39.3%) female;mean age of 26.3 years) were tested during 2004-2006 for hepatitis B surface antigen(HBsAg) and antibodies to hepatitis B virus(anti-HBs) by ELISA.RESULTS:The HBsAg and anti-HBs prevalence were 9.5% and 28.7%,respectively.The highest HBsAg prevalence was evident in the younger age group,such as in schoolchildren(11.8%) and the military(10.6%).Consequently,the anti-HBs prevalence increased with age,from 21.2% in schoolchildren(mean age:15.7 years),to 36.3% in pregnant women(mean age:26.3 years) and 29.7% in voluntary blood donors(mean age:40.1 years).There were no significant differences between males and females.CONCLUSION:Despite the estimated two-fold reduction of HBsAg prevalence in the general population from about 18%-19% to 9.5%,Albania remains a highly endemic country(i.e.over 8% of HBsAg prevalence rate). | Bashkim Resuli Skerdi Prifti Bledar Kraja Tatjana Nurka Mimoza Basho Edita Sadiku | 2009 | World Journal of Gastroenterology2009，15，7： | 9 |
| 3 | Effectiveness of the P3-Speller in Brain-Computer Interfaces for Amyotrophic Lateral Sclerosis Patients: A Systematic Review and Meta-Analysis显示文摘 | Marchetti M Priftis K | 2014 | Frontiers in Neuroengineering2014，7，： | 1 |
| 4 | Does off-pump coronary revascularization reduce the release of the cerebral markers,S-100B and NSE显示文摘 | Bonacchi M Prifti E Maiani M | 2006 | Heart Lung Circ2006，15，5： | 1 |
| 5 | Regulation of matrix metalloproteinases and their inhibitors in uterine endometrial cells of patients with and without endometriosis 显示文摘 | Sillem M Prifti S Koch A | 2001 | Eur J Obstet Gynecol Reprod Biol2001，95，2： | 1 |
| 6 | Respiratory dysfunction after coronary artery bypass grafting employing bilateral internal mammary arteries the influence of intact pleura显示文摘 | Prifti E Giunti G | 2001 | Eur J Cardiothorae Surg2001，19，6： | 1 |
| 7 | Bronchial hyperresponsiveness, atopy, and bronchoalveolar lavage eosinophils in persistent middle lobe syndrome 显示文摘 | Priftis KN | 2006 | Pediatr Pulmonol2006，41，9： | 1 |
| 8 | Explicit versus implicit processing of representational space in neglect:dissociations in accessing the mental number line显示文摘 | Priftis K Zorzi M Meneghello F | 2006 | J Cogn Neurosci2006，18，4： | 1 |
| 9 | Postoperative outcome in patients with anomalous origin of one pulmonary artery branch from the aorta显示文摘 | Prifti E Crucean A Bonacchi M | | 0，，01： | 1 |
| 10 | Anomalous origin of the right pulmonary artery from the ascending aorta显示文摘 | Prifti E Bonacchi M Murzi B | 2004 | J Card Surg2004，19，2： | 1 |
| 11 | A modified technique for repair of the anomalous origin of the right pulmonary显示文摘 | Prifti E Frati G Crucean A | | 0，，01： | 1 |
| 12 | Repair of complete atrio- ventricular septal defect with tetralogy of Fallot: our experience and literature review显示文摘 | Prifti E Bonacchi M Bernabei M | 2004 | J Card Surg2004，19，2： | 1 |
| 13 | Secretory hyperrespon?siveness and pulmonary mucus hypersecretion显示文摘 | Rubin BK Priftis KN Schmidt Ill | 2014 | Chest2014，146，2： | 1 |
| 14 | The role of timely intervention in middle lobe syndrome in children 显示文摘 | Priftis KN | 2005 | Chest2005，128，4： | 1 |
| 15 | Pre-operative evaluation of the trachea in a child with pulmo-nary artery sling using 3-dimensional computed tomo-graphic imaging and virtual bronchoscopy 显示文摘 | Kagadis GC Panagiotopoulou EC Priftis KN | 2007 | J PediatrSurg2007，42，5： | 1 |
| 16 | N-acetylcysteine exerts therapeutic action in a rat model of allergic rhinitis显示文摘 | Guibas G V Spandou E Meditskou S Vyzantiadis T A Priftis K N Anogianakis G | 2013 | Int Forum Allergy Rhinol2013，3，： | 1 |
| 17 | Beating heart ischemic mitralvalve repair and coronary revascularization in patients with impaired left ventricular function显示文摘 | Prifti E Bonacchi M Giunit G | 2003 | J Card Surg2003，18，5： | 1 |
| 18 | Regulation of matrix metalloproteinases and their inhibitors in uterine endomertrial cells of patients without endometriosis 显示文摘 | Prifti S Koch A | 2001 | Eur J Obstet Gynecol Reprad Biol2001，95，2： | 1 |
| 19 | Regulation of matrix metalloproteinases and their inhibitors in uterine endometrial cells of patients with and without endometriosis显示文摘 | Prifti S Koch A | 2001 | Eur J Obstet Gynecol Reprod Biol2001，95，2： | 1 |
| 20 | Childhood over- weight/obesity and asthma: is there a link? A systematic review of recent epidemiologic evidence显示文摘 | Papoutsakis C Priftis KN Drakouli M | 2013 | J Acad Nutr Diet2013，113，1： | 1 |
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